Testing Status of Agents at NTP
o-Chlorobenzalmalononitrile (CS)
CASRN: 2698-41-1
Related: CHLOROBENZALMALONONITRILE (CAS 35254-70-7)
Formula: C10-H5-CL-N2
Synonyms/Common Names:
- 2-CHLOROBENZALONONITRILE
- CS
- MALONONITRILE, O-CHLOROBENZYLIDENE-
- PROPANEDINITRILE ((2-CHLOROPENYL)METHYLENE)- (9CI)
Known Uses:
RIOT CONTROL AGENT. (TDB)
Short-Term Toxicity
- 14-Day (Inhalation)
(C55118) Completed
- NTIS No. PB90-256280
(Peer Review 11/20/1989)
Citation: Toxicology and Carcinogenesis Studies of CS2 (94 o-Chlorobenzalmalononitrile, CAS No. 2698-41-1) in F344/N Rats and B6C3F1 Mice (Inhalation Studies) - Rats: F344/N; Mice: B6C3F1
- NTIS No. PB90-256280
(Peer Review 11/20/1989)
- 13-Week (Inhalation)
(C55118) Completed
- NTIS No. PB90-256280
(Peer Review 11/20/1989)
Citation: Toxicology and Carcinogenesis Studies of CS2 (94 o-Chlorobenzalmalononitrile, CAS No. 2698-41-1) in F344/N Rats and B6C3F1 Mice (Inhalation Studies) - Rats: F344/N; Mice: B6C3F1
- Dose: 0,.4,6.0 MG/M3/10 PER GROUP
- NTIS No. PB90-256280
(Peer Review 11/20/1989)
Long-Term Carcinogenicity
- 2-YEAR (Inhalation)
(C55118) Report Complete
- TR-377 (NTIS No. PB90-256280)
(Peer Review 11/20/1989)
Toxicology and Carcinogenesis Studies of CS2 (94 o-Chlorobenzalmalononitrile, CAS No. 2698-41-1) in F344/N Rats and B6C3F1 Mice (Inhalation Studies) - Rats: F344/N; Mice: B6C3F1
- Carcinogenesis Results
- Male Rats No Evidence
- Female Rats No Evidence
- Male Mice No Evidence
- Female Mice No Evidence
- Dose: R: 0,.075,.25,.75, M: 0,.75,1.5 MG/M3/50 PER GROUP
- TR-377 (NTIS No. PB90-256280)
(Peer Review 11/20/1989)
Genetic Toxicology
- In Vitro Cytogenetics (CA/SCE)
(171099) Completed
- Chromosome Aberation Positive
- Sister Chromatid Exchange Positive
- Mouse Lymphoma
(668414) Completed
- Citation: McGregor, D.B., Brown, A., Cattanach, P., Edwards, I., McBride, D., and Caspary, W.J. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay to coded chemicals. II. 18 coded chemicals. Environ. Molec. Mutagen. Vol. 11 (1988) 91-118
- Positive
- Salmonella
(704784) Completed
- Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., Mortelmans, K., and Speck, W. Salmonella mutagenicity tests. III. Results from the testing of 225 chemicals Environ. Mutagen. Vol. 9 (Suppl 9) (1987) 1-109
- Inconclusive
- Salmonella
(825580) Completed
- Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., Mortelmans, K., and Speck, W. Salmonella mutagenicity tests. III. Results from the testing of 225 chemicals Environ. Mutagen. Vol. 9 (Suppl 9) (1987) 1-109
- Inconclusive
Web page last updated on January 22, 2009