Testing Status of Agents at NTP
4-Nitroanthranilic acid
CASRN: 619-17-0
Formula: C7-H6-N2-O4
Synonyms/Common Names:
- 2-AMINO-4-NITROBENZOIC ACID (9CI)
Known Uses:
FORMERLY USED AS DYE INTERMEDIATE
Short-Term Toxicity
- 14-Day (Dosed-Feed)
(C01945) Completed
- NTIS No. PB286942
(Peer Review 06/29/1978)
Citation: Bioassay of 4-Nitroanthranilic Acid for Possible Carcinogenicity (CAS No. 619-17-0) - Rats: F344/N; Mice: B6C3F1
- NTIS No. PB286942
(Peer Review 06/29/1978)
- 13-Week (Dosed-Feed)
(C01945) Completed
- NTIS No. PB286942
(Peer Review 06/29/1978)
Citation: Bioassay of 4-Nitroanthranilic Acid for Possible Carcinogenicity (CAS No. 619-17-0) - Rats: F344/N; Mice: B6C3F1
- Dose: 0,0.45,1.35 %/5 PER GROUP
- NTIS No. PB286942
(Peer Review 06/29/1978)
Long-Term Carcinogenicity
- 2-Year (Dosed-Feed)
(C01945) Report Complete
- TR-109 (NTIS No. PB286942)
(Peer Review 06/29/1978)
Bioassay of 4-Nitroanthranilic Acid for Possible Carcinogenicity (CAS No. 619-17-0) - Rats: F344/N; Mice: B6C3F1
- Carcinogenesis Results
- Male Rats Negative
- Female Rats Negative
- Male Mice Negative
- Female Mice Negative
- Dose: R: 0,.46,1.5 (AVG), M: 0,.46,1.0 (AVG) %/50 PER GROUP
- TR-109 (NTIS No. PB286942)
(Peer Review 06/29/1978)
Genetic Toxicology
- In Vitro Cytogenetics (CA/SCE)
(235278) Completed
- Chromosome Aberation Positive
- Sister Chromatid Exchange Positive
- Drosophila
(573798) Completed
- Citation: Woodruff, R.C., Mason, J.M., Valencia, R., and Zimmering, S. Chemical mutagenesis testing in Drosophila: V. Results of 53 coded compounds tested for the National Toxicology Program. Environ. Mutagen. Vol. 7 (1985) 677-702
- Reciprocal Translocation/Sex-Linked Recessive Lethal Negative
- Mouse Lymphoma
(721150) Completed
- Positive
- Salmonella
(027486) Completed
- Citation: Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
- Positive
- Salmonella
(421216) Completed
- Citation: Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
- Positive
Web page last updated on January 22, 2009