Testing Status of Agents at NTP
Ziram
CASRN: 137-30-4
Formula: C6 H12 N2 S4 ZN
Synonyms/Common Names:
- (T-4)-BIS(DIMETHYLCARBAMODITHIOATO-S,S')ZINC (9CI)
Known Uses:
FUNGICIDE & ACCELERATOR IN RUBBER VULCANIZATION
Short-Term Toxicity
- 2-WEEK (Dosed-Feed)
(C50442) Completed
- NTIS No. PB83-202622
(Peer Review 12/16/1981)
Citation: Carcinogenesis Bioassay of Ziram (CAS No. 137-30-4) in F344/N Rats and B6C3F1 Mice (Feed Study) - Rats: F344/N; Mice: B6C3F1
- NTIS No. PB83-202622
(Peer Review 12/16/1981)
- 13-WEEK (Dosed-Feed)
(C50442) Completed
- NTIS No. PB83-202622
(Peer Review 12/16/1981)
Citation: Carcinogenesis Bioassay of Ziram (CAS No. 137-30-4) in F344/N Rats and B6C3F1 Mice (Feed Study) - Rats: F344/N; Mice: B6C3F1
- Dose: R&M: 0, 300, 600, 1200, 2500, OR 5000 PPM
- NTIS No. PB83-202622
(Peer Review 12/16/1981)
Long-Term Carcinogenicity
- 2-YEAR (Dosed-Feed)
(C50442) Report Complete
- TR-238 (NTIS No. PB83-202622)
(Peer Review 12/16/1981)
Carcinogenesis Bioassay of Ziram (CAS No. 137-30-4) in F344/N Rats and B6C3F1 Mice (Feed Study) - Rats: F344/N; Mice: B6C3F1
- Carcinogenesis Results
- Male Rats Positive
- Female Rats Negative
- Male Mice Negative
- Female Mice Equivocal
- Dose: R: 0, 300, OR 600 PPM M: 0, 600, OR 1200 PPM
- TR-238 (NTIS No. PB83-202622)
(Peer Review 12/16/1981)
Genetic Toxicology
- Chromosome Aberrations
(880520) Completed
- Mice
- Chromosome Aberation Negative
- In Vitro Cytogenetics (CA/SCE)
(054163) Completed
- Citation: Gulati, D., Witt, K., Anderson, B., Zeiger, E.,and Shelby, M. Chromosome aberration and sister chromatid exchange test in Chinese hamster ovary cells in vitro III: Results with 27 chemicals Environ. Molec. Mutagen. Vol. 13 (1989) 133-193
- Chromosome Aberation Positive
- Sister Chromatid Exchange Negative
- Drosophila
(075511) Completed
- Citation: Foureman, P., Mason, J.M., Valencia, R., Zimmering, S. Chemical Mutagenesis Testing in Drosophila. X. Results of 70 coded compounds tested for the National Toxicology Program. Environ. Molec. Mutagen. Vol. 23 (1994) 208-227
- Sex-Linked Recessive Lethal Positive
- Reciprocal Translocation Negative
- Mouse Lymphoma
(746976) Completed
- Citation: McGregor, D., Brown, A., Cattanach, P., Edwards, I., McBride, D., Riach, C., and Caspary, W. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay: III. 72 coded chemicals. Environ. Molec. Mutagen. Vol. 12 (1988) 85-154
- Positive
- Salmonella
(356540) Completed
- Citation: Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142
- Positive
- Sister Chromatid Exchanges
(880520) Completed
- Mice
- Sister Chromatid Negative (Nonstandard Protocol)
Web page last updated on January 22, 2009