National Toxicology Program

CASRN: 6109-97-3

Formula: C14 H14 N2.H CL

Synonyms/Common Names:

• 9-ETHYL-9H-CARBAZOL-3-AMINE MONOHYDROCHLORIDE (9CI)

Known Uses:

PIGMENTS

Short-Term Toxicity

• 14-Day (Dosed-Feed)  (C03043) Completed 
  • NTIS No. PB287126  (Peer Review 06/29/1978)
    Citation: Bioassay of 3-Amino-9-ethylcarbazole Hydrochloride for Possible Carcinogenicity (CAS No. 132-32-1)
  • Rats: F344/N; Mice: B6C3F1
• 13-Week (Dosed-Feed)  (C03043) Completed 
  • NTIS No. PB287126  (Peer Review 06/29/1978)
    Citation: Bioassay of 3-Amino-9-ethylcarbazole Hydrochloride for Possible Carcinogenicity (CAS No. 132-32-1)
  • Rats: F344/N; Mice: B6C3F1
  • Dose: 0,40,1440 PPM/5 PER GROUP

Long-Term Carcinogenicity

• 2-Year (Dosed-Feed)  (C03043) Report Complete 
  • TR-093 (NTIS No. PB287126)  (Peer Review 06/29/1978)
    Bioassay of 3-Amino-9-ethylcarbazole Hydrochloride for Possible Carcinogenicity (CAS No. 132-32-1)
  • Rats: F344/N; Mice: B6C3F1
  • Carcinogenesis Results
  • Male Rats Positive 
  • Female Rats Positive 
  • Male Mice Positive 
  • Female Mice Positive 
  • Dose: R: 0,800,2000, M: 0,800,1200 PPM/50 PER GROUP

Genetic Toxicology

• In Vitro Cytogenetics (CA/SCE)  (688225) Completed 
  • Chromosome Aberation Negative 
  • Sister Chromatid Exchange Positive 
• Salmonella  (918212) Completed 
  • Citation: Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142
  •  Positive