National Toxicology Program

CASRN: 115-07-1

Formula: C3-H6

Synonyms/Common Names:

• 1-PROPENE (9CI)

Known Uses:

PRODUCTION OF POLYPROPYLENE PLASTICS AND OTHER CHEMICALS

Long-Term Carcinogenicity

• 2-YEAR (Inhalation)  (C50077) Report Complete 
  • TR-272 (NTIS No. PB86-145521)  (Peer Review 06/29/1983)
    Toxicology and Carcinogenesis Studies of Propylene (CAS No. 115-07-1) in F344/N Rats and B6C3F1 Mice (Inhalation Studies)
  • Rats: F344/N; Mice: B6C3F1
  • Carcinogenesis Results
  • Male Rats No Evidence 
  • Female Rats No Evidence 
  • Male Mice No Evidence 
  • Female Mice No Evidence 
  • Dose: 0,5000,10000 PPM/50 PER GROUP

Genetic Toxicology

• Drosophila  (858707) Completed 
  • Citation: Foureman, P., Mason, J.M., Valencia, R., Zimmering, S. Chemical Mutagenesis Testing in Drosophila. X. Results of 70 coded compounds tested for the National Toxicology Program. Environ. Molec. Mutagen. Vol. 23 (1994) 208-227
  • Reciprocal Translocation/Sex-Linked Recessive Lethal Negative 
• Mouse Lymphoma  (537921) Completed 
  • Citation: McGregor, D., Brown, A.G., Cattanach, P., Edwards, I., McBride, D., Riach, C., Shepherd, W., and Caspary, W. Responses of the L5178Y mouse lymphoma forward mutation assay: V. Gases and vapors. Environ. Molec. Mutagen. Vol. 17 (1991) 122-129
  •  Negative 
• Salmonella  (779144) Completed 
  •  Positive