Testing Status of Agents at NTP
1-Nitronaphthalene
CASRN: 86-57-7
Formula: C10 H7 N O2
Synonyms/Common Names:
- ALPHA-NITRONAPHTHALENE
Known Uses:
DYE INTERMEDIATE; DEBLOOMING AGENT FOR PETROLEUM OILS (MERCK 1989)
Short-Term Toxicity
- 14-Day (Dosed-Feed)
(C01956) Completed
- NTIS No. PB282310
(Peer Review 01/18/1978)
Citation: Bioassay of 1-Nitronaphthalene for Possible Carcinogenicity (CAS No. 86-57-7) - Rats: F344/N; Mice: B6C3F1
- NTIS No. PB282310
(Peer Review 01/18/1978)
- 13-Week (Dosed-Feed)
(C01956) Completed
- NTIS No. PB282310
(Peer Review 01/18/1978)
Citation: Bioassay of 1-Nitronaphthalene for Possible Carcinogenicity (CAS No. 86-57-7) - Rats: F344/N; Mice: B6C3F1
- Dose: 0,0.05,0.15 %/5 PER GROUP
- NTIS No. PB282310
(Peer Review 01/18/1978)
Long-Term Carcinogenicity
- 2-Year (Dosed-Feed)
(C01956) Report Complete
- TR-064 (NTIS No. PB282310)
(Peer Review 01/18/1978)
Bioassay of 1-Nitronaphthalene for Possible Carcinogenicity (CAS No. 86-57-7) - Rats: F344/N; Mice: B6C3F1
- Carcinogenesis Results
- Male Rats Negative
- Female Rats Negative
- Male Mice Negative
- Female Mice Negative
- Dose: R: 0,.06,.18 (AVG), M: 0,.6,.12 (AVG) %/50 PER GROUP
- TR-064 (NTIS No. PB282310)
(Peer Review 01/18/1978)
Genetic Toxicology
- In Vitro Cytogenetics (CA/SCE)
(153730) Completed
- Chromosome Aberation Weakly Positive
- Sister Chromatid Exchange Negative
- Drosophila
(062555) Completed
- Citation: Valencia, R., Mason, J.M., Woodruff, R.C., and Zimmering, S. Chemical mutagenesis testing in Drosophila: III. Results of 48 coded compounds tested for the National Toxicology Program. Environ. Mutagen. Vol. 7 (1985) 325-348
- Reciprocal Translocation/Sex-Linked Recessive Lethal Negative
- Salmonella (NCI)
(CV-271) Completed
- Citation: Dunkel, V., Zeiger, E., Brusick, D., McCoy, E., McGregor, D., Mortelmans, K., Rosenkranz, H., and Simmon, V. (1985) Reproducibility of microbial mutagenicity assays. II. Testing of carcinogens and noncarcinogens in Salmonella typhimurium and Escerichia coli. Environ. Mutagen. 7 (Suppl 5): 1-248.
- Citation: Dunkel, V., Zeiger, E., Brusick, D., McCoy, E., McGregor, D., Mortelmans, K., Rosenkranz, H., and Simmon, V. Reproducibility of microbial mutagenicity assays. II. Testing of carcinogens and noncarcinogens in Salmonella typhimurium and Escerichia coli Environ. Mutagen. Vol. 7 (Suppl 5) (1985) 1-248
- Salmonella-NCI Positive
- Salmonella
(983172) Completed
- Citation: Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
- Citation: Dunkel, V., Zeiger, E., Brusick, D., McCoy, E., McGregor, D., Mortelmans, K., Rosenkranz, H., and Simmon, V. (1985) Reproducibility of microbial mutagenicity assays. II. Testing of carcinogens and noncarcinogens in Salmonella typhimurium and Escerichia coli. Environ. Mutagen. 7 (Suppl 5): 1-248.
- Positive
Web page last updated on January 22, 2009