Testing Status of Agents at NTP
p,p'-Dichlorodiphenyl dichloroethylene
CASRN: 72-55-9
Formula: C14-H8-CL4
Synonyms/Common Names:
- BENZENE, 1,1'-(DICHLOROETHENYLIDENE)BIS(4-CHLORO (9CI)
- BENZENE, 1,1'-(DICHLOROETHYLENYLIDENE)BIS(4-CHLORO- (9CI)
- P,P'-DDE
- P,P-DICHLORODIPHENOLDICHLOROETHYLENE
- p,p'-Dichlorodiphenyl dichloroethylene
Known Uses:
INSECTICIDE
Short-Term Toxicity
- 14-Day (Dosed-Feed)
(C00555) Completed
- NTIS No. PB286367
(Peer Review 06/24/1978)
Citation: Bioassays of DDT, TDE, and p,p'-DDE for Possible Carcinogenicity (CAS No. 50-29-3, CAS No. 72-54-8, CAS No. 72-55-9) - Rats: Osborne Mendel; Mice: B6C3F1
- NTIS No. PB286367
(Peer Review 06/24/1978)
- 13-Week (Dosed-Feed)
(C00555) Completed
- NTIS No. PB286367
(Peer Review 06/24/1978)
Citation: Bioassays of DDT, TDE, and p,p'-DDE for Possible Carcinogenicity (CAS No. 50-29-3, CAS No. 72-54-8, CAS No. 72-55-9) - Rats: Osborne Mendel; Mice: B6C3F1
- Dose: R: 0,316,3160, M: 0,139,519 PPM/5 PER GROUP
- NTIS No. PB286367
(Peer Review 06/24/1978)
Long-Term Carcinogenicity
- 2-Year (Dosed-Feed)
(C00555) Report Complete
- TR-131 (NTIS No. PB286367)
(Peer Review 06/24/1978)
Bioassays of DDT, TDE, and p,p'-DDE for Possible Carcinogenicity (CAS No. 50-29-3, CAS No. 72-54-8, CAS No. 72-55-9) - Rats: Osborne Mendel; Mice: B6C3F1
- Carcinogenesis Results
- Male Rats Negative
- Female Rats Negative
- Male Mice Positive
- Female Mice Positive
- Dose: MR: 0,437,839 (AVG), FR: 0,242,462 (AVG), M: 0,148,261 (AVG) PPM/50 PER GROUP
- TR-131 (NTIS No. PB286367)
(Peer Review 06/24/1978)
Genetic Toxicology
- In Vitro Cytogenetics (CA/SCE)
(354419) Completed
- Citation: Galloway, S., Armstrong, M., Reuben, C., Colman, S., Brown, B., Cannon, C., Bloom, A., Nakamura, F., Ahmed, M., Duk, S., Rimpo, J., Margolin, B., Resnick, M., Anderson, B., and Zeiger, E. Chromosome aberration and sister chromatid exchanges in Chinese hamster ovary cells: Evaluations of 108 chemicals. Environ. Molec. Mutagen. Vol. 10 (Suppl 10) (1987) 1-176
- Chromosome Aberation Negative
- Sister Chromatid Exchange Weakly Positive
- Drosophila
(320322) Completed
- Citation: Valencia, R., Mason, J.M., Woodruff, R.C., and Zimmering, S. Chemical mutagenesis testing in Drosophila: III. Results of 48 coded compounds tested for the National Toxicology Program. Environ. Mutagen. Vol. 7 (1985) 325-348
- Sex-Linked Recessive Lethal Positive
- Reciprocal Translocation Negative
- Mouse Lymphoma
(202120) Completed
- Citation: McGregor, D., Brown, A., Cattanach, P., Edwards, I., McBride, D., Riach, C., and Caspary, W. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay: III. 72 coded chemicals. Environ. Molec. Mutagen. Vol. 12 (1988) 85-154
- Positive
- Salmonella
(161546) Completed
- Negative
- Salmonella
(797103) Completed
- Citation: Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
- Negative
Web page last updated on January 22, 2009