Testing Information

Testing Status of Agents at NTP

Quercetin

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http://ntp.niehs.nih.gov/go/TS-10161-R

CASRN: 117-39-5

Formula: C15-H10-O7

Synonyms/Common Names:

  • 2-(3,4-DIHYDROXYPHENYL)-3,5,7-TRIHYDROXY-4H-1-BENZOPYRAN-4-ONE (9CI)

Known Uses:

CAPILLARY PROTECTANT (MERCK 1989).

Long-Term Carcinogenicity

  • 2-YEAR (Dosed-Feed)  (C60106) Report Complete 
    • TR-409 (NTIS No. PB93-147478)  (Peer Review 03/12/1991)
      Toxicology and Carcinogenesis Studies of Quercetin (CAS No. 117-39-5) in F344 Rats (Feed Studies)
    • Rats: F344/N
    • Carcinogenesis Results
      • Male Rats Some Evidence 
      • Female Rats No Evidence 
    • Dose: RATS ONLY:0,1000,10000,40000 PPM/50 PER GROUP

Genetic Toxicology

  • In Vitro Cytogenetics (CA/SCE)  (305922) Completed 
    • Chromosome Aberation Positive 
    • Sister Chromatid Exchange Positive 
  • Salmonella  (200400) Completed 
    • Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelman, K. Salmonella Mutagenicity Tests V. Results from the Testing of 311 Chemicals Environ. Molec. Mutagen. Vol. 19 (Suppl 21) (1992) 2-141
    •  Positive 

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Web page last updated on January 22, 2009