National Toxicology Program

CASRN: 108171-26-2

Formula: C12-H19-CL7

Synonyms/Common Names:

• CERECLOR 54
• CHLOROWAX 500C

Known Uses:

ADDITIVE FOR EXTREME PRESSURE LUBRICANT; FLAME RETARDANT IN RUBBER, PLASTIC, AND PAINT

Short-Term Toxicity

• 14-Day (Gavage)  (C53587) Completed 
  • NTIS No. PB86-248101  (Peer Review 08/14/1985)
    Citation: Toxicology and Carcinogenesis Studies of Chlorinated Paraffins (C12, 60Chlorine) (CAS No. 108171-26-2) in F344/N Rats and B6C3F1 Mice (Gavage Studies)
  • Rats: F344/N; Mice: B6C3F1
• 13-Week (Gavage)  (C53587) Completed 
  • NTIS No. PB86-248101  (Peer Review 08/14/1985)
    Citation: Toxicology and Carcinogenesis Studies of Chlorinated Paraffins (C12, 60Chlorine) (CAS No. 108171-26-2) in F344/N Rats and B6C3F1 Mice (Gavage Studies)
  • Rats: F344/N; Mice: B6C3F1
  • Dose: R: 0,313,5000, M: 0,469,7500 MG/KG/5 PER GROUP

Long-Term Carcinogenicity

• 2-YEAR (Gavage)  (C53587) Report Complete 
  • TR-308 (NTIS No. PB86-248101)  (Peer Review 08/14/1985)
    Toxicology and Carcinogenesis Studies of Chlorinated Paraffins (C12, 60Chlorine) (CAS No. 108171-26-2) in F344/N Rats and B6C3F1 Mice (Gavage Studies)
  • Rats: F344/N; Mice: B6C3F1
  • Carcinogenesis Results
  • Male Rats Clear Evidence 
  • Female Rats Clear Evidence 
  • Male Mice Clear Evidence 
  • Female Mice Clear Evidence 
  • Dose: R: 0,312,625, M: 0,125,250 MG/KG/50 PER GROUP

Genetic Toxicology

• In Vitro Cytogenetics (CA/SCE)  (132281) Completed 
  • Citation: Anderson, B.E., Zeiger, E., Shelby, M.D., Resnick, M.A., Gulati, D.K., Ivett, J.L., and Loveday, K.S. Chromosome aberration and sister chromatid exchange test results with 42 chemicals. Environ. Molec. Mutagen. Vol. 16 (Suppl 18) (1990) 55-137
  • Chromosome Aberation Positive 
  • Sister Chromatid Exchange Positive 
• Mouse Lymphoma  (333321) Completed 
  •  Positive 
• Salmonella  (731132) Completed 
  • Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., Mortelmans, K., and Speck, W. Salmonella mutagenicity tests. III. Results from the testing of 225 chemicals Environ. Mutagen. Vol. 9 (Suppl 9) (1987) 1-109
  •  Negative