Testing Status of Agents at NTP
Pentachloronitrobenzene
CASRN: 82-68-8
Formula: C6-CL5-N-O2
Synonyms/Common Names:
- BATRILEX
Known Uses:
FUNGICIDE, SOIL FUMIGANT AND SEED TREATMENT
Short-Term Toxicity
- 14-Day (Dosed-Feed)
(C00419A) Completed
- NTIS No. PB281732
(Peer Review 01/18/1978)
Citation: Bioassay of Pentachloronitrobenzene for Possible Carcinogenicity (CAS No. 82-68-8) - Rats: Osborne Mendel; Mice: B6C3F1
- NTIS No. PB281732
(Peer Review 01/18/1978)
- 13-Week (Dosed-Feed)
(C00419A) Completed
- NTIS No. PB281732
(Peer Review 01/18/1978)
Citation: Bioassay of Pentachloronitrobenzene for Possible Carcinogenicity (CAS No. 82-68-8) - Rats: Osborne Mendel; Mice: B6C3F1
- Dose: 0,2150,46400 PPM/5 PER GROUP
- NTIS No. PB281732
(Peer Review 01/18/1978)
- 13-Week (Dosed-Feed)
(C00419B) Completed
- NTIS No. PB87-208633
(Peer Review 03/26/1986)
Citation: Toxicology and Carcinogenesis Studies of Pentachloronitrobenzene (CAS No. 82-68-8) in B6C3F1 Mice (Feed Studies) - Mice: B6C3F1
- Dose: MM: 0,.125,2.00, FM: 0,.25,4.00 %/10 PER GROUP
- NTIS No. PB87-208633
(Peer Review 03/26/1986)
Long-Term Carcinogenicity
- 2-Year (Dosed-Feed)
(C00419A) Report Complete
- TR-061 (NTIS No. PB281732)
(Peer Review 01/18/1978)
Bioassay of Pentachloronitrobenzene for Possible Carcinogenicity (CAS No. 82-68-8) - Rats: Osborne Mendel; Mice: B6C3F1
- Carcinogenesis Results
- Male Rats Negative
- Female Rats Negative
- Male Mice Negative
- Female Mice Negative
- Dose: MR: 0,5417,10064 (AVG), FR: 0, 7875, 14635 (AVG), MM: 0, 2606, 5213 (AVG), FM: 0, 4043, 8187 (AVG) PPM/50 PER GROUP
- TR-061 (NTIS No. PB281732)
(Peer Review 01/18/1978)
- 2-YEAR (Dosed-Feed)
(C00419B) Report Complete
- TR-325 (NTIS No. PB87-208633)
(Peer Review 03/26/1986)
Toxicology and Carcinogenesis Studies of Pentachloronitrobenzene (CAS No. 82-68-8) in B6C3F1 Mice (Feed Studies) - Mice: B6C3F1
- Carcinogenesis Results
- Male Mice No Evidence
- Female Mice No Evidence
- Dose: 0,2500,5000 PPM/50 PER GROUP
- TR-325 (NTIS No. PB87-208633)
(Peer Review 03/26/1986)
Genetic Toxicology
- In Vitro Cytogenetics (CA/SCE)
(027750) Completed
- Chromosome Aberation Positive
- Sister Chromatid Exchange Positive
- In Vitro Cytogenetics (CA/SCE)
(114657) Completed
- Citation: Galloway, S., Armstrong, M., Reuben, C., Colman, S., Brown, B., Cannon, C., Bloom, A., Nakamura, F., Ahmed, M., Duk, S., Rimpo, J., Margolin, B., Resnick, M., Anderson, B., and Zeiger, E. Chromosome aberration and sister chromatid exchanges in Chinese hamster ovary cells: Evaluations of 108 chemicals. Environ. Molec. Mutagen. Vol. 10 (Suppl 10) (1987) 1-176
- Chromosome Aberation Positive
- Sister Chromatid Exchange Negative
- Mouse Lymphoma
(303135) Completed
- Negative
- Salmonella
(251113) Completed
- Citation: Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142
- Negative
Web page last updated on January 22, 2009