Summaries & Associations of Study Results
Levels from TR-523 Diisopropylcarbodiimide
Target Organs and Levels of Evidence
NTP Technical Report Number 523
Produced from Chemtrack Database 01/04/06
| CHEMICAL/ CAS NUMBER | PEER REVIEW DATE | PRIMARY USES | ROUTE/EXPOSURE LEVELS | STUDY LABORATORY |
|---|---|---|---|---|
| DIISOPROPYLCARBODIIMIDE 693-13-0 |
09/28/05 | AS A PEPTIDE COUPLING REAGENT; AS A CONDENSING REAGENT IN DIPEPTIDE SYNTHESIS; IN PREPARATION OF POLYIMIDE PRECURSOR COATINGS FOR ELECTROPHORETIC IMAGE DISPLAY FABRICATION; AS A MILITARY NERVE AGENT STABILIZER. | Topical Application R&M: 0, 10, 20, OR 40 MG/KG; 50/SEX/SPECIES | Southern Research Institute |
| LEVELS OF EVIDENCE OF CARCINOGENICITY--ORGAN/TISSUE (NEOPLASM): | ||||
| MR: NO EVIDENCE | ||||
| NON-NEOPLASTIC LESIONS: | BRAIN: HEMORRHAGE; NEURONAL NECROSIS; FIBRINOID ARTERIOLE NECROSIS | |||
| LUNG: HEMORRHAGE | ||||
| SKIN: EPIDERMAL HYPERPLASIA; CHRONIC INFLAMMATION | ||||
| FR: NO EVIDENCE | ||||
| NON-NEOPLASTIC LESIONS: | LUNG: CHRONIC INFLAMMATION; ALVEOLAR EPITHELIAL HYPERPLASIA | |||
| SKIN: EPIDERMAL HYPERPLASIA; CHRONIC INFLAMMATION | ||||
| MM: NO EVIDENCE | ||||
| NON-NEOPLASTIC LESIONS: | SKIN: EPIDERMAL HYPERPLASIA; DERMAL FOCAL INFLAMMATION | |||
| FM: NO EVIDENCE | ||||
Web page last updated on October 02, 2007
