Summaries & Associations of Study Results
TR-496 Fumonisin B1
Target Organs and Levels of Evidence
NTP Technical Report Number 496
Produced from Chemtrack Database 09/19/01
| CHEMICAL/ CAS NUMBER | PEER REVIEW DATE | PRIMARY USES | ROUTE/EXPOSURE LEVELS | STUDY LABORATORY |
|---|---|---|---|---|
| FUMONISIN B1 116355-83-0 |
05/21/99 | MYCOTOXIN PRODUCED BY CERTAIN STRAINS OF FUSARIUM MONILIFORME, A COMMONLY OCCURRING FUNGI ON U.S. AGRICULTURAL PRODUCTS, ESPECIALLY CORN. NO KNOWN USES | Dosed-Feed R&M: 0, 5, 15, 50, 100, OR 150 PPM | National Center for Toxicological Research |
| LEVELS OF EVIDENCE OF CARCINOGENICITY--ORGAN/TISSUE (NEOPLASM): | ||||
| MR: CLEAR EVIDENCE | KIDNEY TUBULAR CELL: ADENOMA 0/48 0/40 0/48 2/48 5/48 OR CARCINOMA 0/48 0/40 0/48 7/48 10/48 COMBINED 0/48 0/40 0/48 9/48 15/48 | |||
| NON-NEOPLASTIC LESIONS: | KIDNEY: TUBULAR CELL EPITHELIAL HYPERPLASIA | |||
| FR: NO EVIDENCE | ||||
| MM: NO EVIDENCE | ||||
| NON-NEOPLASTIC LESIONS: | LIVER: HYPERTROPHY | |||
| FM: CLEAR EVIDENCE | LIVER: ADENOMA 5/47 3/48 1/48 16/47 31/45 OR CARCINOMA 0/47 0/48 0/48 10/47 9/45 COMBINED 5/47 3/48 1/48 19/47 39/45 | |||
| NON-NEOPLASTIC LESIONS: | LIVER: HYPERTROPHY; APOPTOSIS | |||
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