Summaries & Associations of Study Results
TR-447 Acetonitrile
Target Organs and Levels of Evidence
NTP Technical Report Number 447
Produced from Chemtrack Database 09/19/01
| CHEMICAL/ CAS NUMBER | PEER REVIEW DATE | PRIMARY USES | ROUTE/EXPOSURE LEVELS | STUDY LABORATORY |
|---|---|---|---|---|
| ACETONITRILE 75-05-8 |
06/21/94 | SOLVENT IN HYDROCARBON EXTRACTION PROCESSES. SPECIALTY SOLVENT. CHEMICAL INTERMEDIATE. SEPARATION OF FATTY ACIDS FROM VEGETABLE OILS. PHARMACEUTICALS. (TDB) | Inhalation R: 0, 100, 200, OR 400 PPM M: 0, 50, 100, OR 200 PPM ; 50/GROUP | Battelle Northwest Laboratory |
| LEVELS OF EVIDENCE OF CARCINOGENICITY--ORGAN/TISSUE (NEOPLASM): | ||||
| MR: EQUIVOCAL EVIDENCE | LIVER: ADENOMA 0/48 1/47 1/48 3/48 OR CARCINOMA 1/48 0/47 0/48 3/48 COMBINED 1/48 1/47 1/48 5/48 | |||
| FR: NO EVIDENCE | ||||
| MM: NO EVIDENCE | ||||
| NON-NEOPLASTIC LESIONS: | FORESTOMACH: SQUAMOUS HYPERPLASIA | |||
| FM: NO EVIDENCE | ||||
| NON-NEOPLASTIC LESIONS: | FORESTOMACH: SQUAMOUS HYPERPLASIA | |||
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