Summaries & Associations of Study Results
TR-415 Polysorbate 80 (Glycol)
Target Organs and Levels of Evidence
NTP Technical Report Number 415
Produced from Chemtrack Database 09/19/01
| CHEMICAL/ CAS NUMBER | PEER REVIEW DATE | PRIMARY USES | ROUTE/EXPOSURE LEVELS | STUDY LABORATORY |
|---|---|---|---|---|
| POLYSORBATE 80 (GLYCOL) 9005-65-6 |
07/10/91 | EMULSIFIER AND DISPERSING AGENT FOR INTERNAL MEDICINAL PRODUCTS. DEFOAMER IN FOODS. NEUTRALIZER FOR QUATERNARY AMMONIUM COMPOUNDS. (TDB) | Dosed-Feed 0,2.5,5.0%/20 PER GROUP | Southern Research Institute |
| LEVELS OF EVIDENCE OF CARCINOGENICITY--ORGAN/TISSUE (NEOPLASM): | ||||
| MR: EQUIVOCAL EVIDENCE | ADRENAL GLAND MEDULLA: PHEOCHROMOCYTOMA 21/50 19/50 29/50 | |||
| NON-NEOPLASTIC LESIONS: | ADRENAL GLAND: HYPERPLASIA | |||
| FR: NO EVIDENCE | ||||
| MM: NO EVIDENCE | ||||
| NON-NEOPLASTIC LESIONS: | FORESTOMACH: SQUAMOUS HYPERPLASIA; INFLAMMATION | |||
| FM: NO EVIDENCE | ||||
| NON-NEOPLASTIC LESIONS: | FORESTOMACH: SQUAMOUS HYPERPLASIA; INFLAMMATION; ULCER | |||
Web page last updated on February 10, 2006
