Summaries & Associations of Study Results
TR-410 Naphthalene
Target Organs and Levels of Evidence
NTP Technical Report Number 410
Produced from Chemtrack Database 09/19/01 (updated 2/20/03)
| CHEMICAL/ CAS NUMBER | PEER REVIEW DATE | PRIMARY USES | ROUTE/EXPOSURE LEVELS | STUDY LABORATORY |
|---|---|---|---|---|
| NAPHTHALENE 91-20-3 |
03/11/91 | CHEMICAL INTERMEDIATE, INSECTICIDES, REPELLANTS, ANTISEPTIC, VERMICIDE, SYNTHETIC RESINS; IN VARIOUS COMMERCICAL MOTH REPELLANTS AND TOILET BOWL CLEANERS; TOPICALLY IN VETERINARY MEDICINE. PREPARED FROM COAL TAR. | Inhalation 0,10 (75 mice/sex/group),30 (150 mice/sex/group) PPM | Man Tech, Inc. |
| LEVELS OF EVIDENCE OF CARCINOGENICITY--ORGAN/TISSUE (NEOPLASM): | ||||
| MM: NO EVIDENCE | ||||
| NON-NEOPLASTIC LESIONS: | NASAL CAVITY: INFLAMMATION, CHRONIC; OLFACTORY EPITHELIUM, METAPLASIA; RESPIRATORY EPITHELIUM, HYPERPLASIA | |||
| LUNG: INFLAMMATION, CHRONIC | ||||
| FM: SOME EVIDENCE | LUNG: ALVEOLAR/BRONCHIOLAR ADENOMA 5/68 2/64 28/134 | |||
| NON-NEOPLASTIC LESIONS: | NASAL CAVITY: INFLAMMATION, CHRONIC; OLFACTORY EPITHELIUM, METAPLASIA; RESPIRATORY EPITHELIUM, HYPERPLASIA | |||
| LUNG: INFLAMMATION, CHRONIC | ||||
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