Summaries & Associations of Study Results
TR-394 Acetaminophen (4-Hydroxyacetanilide)
Target Organs and Levels of Evidence
NTP Technical Report Number 394
Produced from Chemtrack Database 09/19/01
| CHEMICAL/ CAS NUMBER | PEER REVIEW DATE | PRIMARY USES | ROUTE/EXPOSURE LEVELS | STUDY LABORATORY |
|---|---|---|---|---|
| ACETAMINOPHEN (4-HYDROXYACETANILIDE) 103-90-2 |
11/19/90 | MANUFACTURE OF AZO DYES, ANALGESIC, INTERMEDIATE FOR PHARMACEUTICALS (HSDB 1990); DERIVATIVE OF P-AMINOPHENOL | Dosed-Feed R&M:0,.06,.3,.6%/60 PER GROUP | T.S.I. Mason Laboratories, Inc. |
| LEVELS OF EVIDENCE OF CARCINOGENICITY--ORGAN/TISSUE (NEOPLASM): | ||||
| MR: NO EVIDENCE | ||||
| NON-NEOPLASTIC LESIONS: | KIDNEY: NEPHROPATHY; TUBULAR HYPERPLASIA | |||
| PARATHYROID GLAND: HYPERPLASIA | ||||
| FR: EQUIVOCAL EVIDENCE | HEMATOPOIETIC SYSTEM: MONONUCLEAR CELL LEUKEMIA 9/50 17/50 15/50 24/50 | |||
| NON-NEOPLASTIC LESIONS: | KIDNEY: NEPHROPATHY | |||
| MM: NO EVIDENCE | ||||
| NON-NEOPLASTIC LESIONS: | THYROID GLAND: FOLLICULAR CELL HYPERPLASIA | |||
| FM: NO EVIDENCE | ||||
| NON-NEOPLASTIC LESIONS: | THYROID GLAND: FOLLICULAR CELL HYPERPLASIA | |||
Web page last updated on February 10, 2006
