Summaries & Associations of Study Results
TR-368 Nalidixic Acid
Target Organs and Levels of Evidence
NTP Technical Report Number 368
Produced from Chemtrack Database 09/19/01
| CHEMICAL/ CAS NUMBER | PEER REVIEW DATE | PRIMARY USES | ROUTE/EXPOSURE LEVELS | STUDY LABORATORY |
|---|---|---|---|---|
| NALIDIXIC ACID 389-08-2 |
03/13/89 | VETERINARY USE AS ANTIBACTERIAL AGENT FOR URINARY INFECTIONS. (TDB) | Dosed-Feed R&M: 0, 2000, 4000 PPM/50 PER GROUP | Physiological Research Laboratory |
| LEVELS OF EVIDENCE OF CARCINOGENICITY--ORGAN/TISSUE (NEOPLASM): | ||||
| MR: CLEAR EVIDENCE | PREPUTIAL GLAND: ADENOMA 2/49 10/49 10/47, PAPILLOMA 1/49 0/49 0/47, OR CARCINOMA 0/49 10/49 12/47 COMBINED 3/49 19/49 20/47 | |||
| FR: CLEAR EVIDENCE | CLITORAL GLAND: ADENOMA 4/46 10/46 11/47, PAPILLOMA 0/46 1/46 0/47, OR CARCINOMA 1/46 4/46 5/47 COMBINED 5/46 15/46 16/47 | |||
| MM: EQUIVOCAL EVIDENCE | SUBCUTANEOUS TISSUE: FIBROMA 1/50 3/50 3/50 OR FIBROSARCOMA 4/50 6/50 11/50 COMBINED 5/50 9/50 14/50 | |||
| FM: NO EVIDENCE | ||||
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