Summaries & Associations of Study Results
TR-360 N,N-Dimethylaniline
Target Organs and Levels of Evidence
NTP Technical Report Number 360
Produced from Chemtrack Database 09/19/01
| CHEMICAL/ CAS NUMBER | PEER REVIEW DATE | PRIMARY USES | ROUTE/EXPOSURE LEVELS | STUDY LABORATORY |
|---|---|---|---|---|
| N,N-DIMETHYLANILINE 121-69-7 |
03/13/89 | DYES, INTERMEDIATES; SOLVENT; MANUFACTURE OF VANILLIN; STABILIZER (ACID RECEPTOR). | Gavage R: 0,3,30, M: 0,15,30 MG/KG/50 PER GROUP | Springborn Inst. for Bioresearch, Inc. |
| LEVELS OF EVIDENCE OF CARCINOGENICITY--ORGAN/TISSUE (NEOPLASM): | ||||
| MR: SOME EVIDENCE | SPLEEN: SARCOMA 0/49 0/49 3/50 OR OSTEOSARCOMA 0/49 0/49 1/50 COMBINED 0/49 0/49 4/50 | |||
| NON-NEOPLASTIC LESIONS: | SPLEEN: FIBROSIS 5/49 2/49 22/50; HEMOSIDEROSIS 43/49 47/49 49/50; METAMORPHOSIS, FATTY 0/49 1/49 10/50 | |||
| FR: NO EVIDENCE | ||||
| MM: NO EVIDENCE | ||||
| FM: EQUIVOCAL EVIDENCE | FORESTOMACH: SQUAMOUS CELL PAPILLOMA 2/50 2/50 8/50 | |||
Web page last updated on February 10, 2006
