Summaries & Associations of Study Results
TR-352 N-Methylolacrylamide
Target Organs and Levels of Evidence
NTP Technical Report Number 352
Produced from Chemtrack Database 09/19/01
| CHEMICAL/ CAS NUMBER | PEER REVIEW DATE | PRIMARY USES | ROUTE/EXPOSURE LEVELS | STUDY LABORATORY |
|---|---|---|---|---|
| N-METHYLOLACRYLAMIDE 924-42-5 |
10/03/88 | PROPOSED FOR USE IN SUNSCREEN PREPARATIONS. POLYMERS FOR COATING, VARNISHES, ADHESIVES, CREASE-PROOF AND WRINKLE-RESISTANT FABRICS, PERMANENT-PRESS TEXTILES BY IRRADIATION BONDING. (TDB,2) | Gavage R: 0,6,12, M: 0,25,50 MG/KG/50 PER GROUP | Battelle Columbus Laboratory |
| LEVELS OF EVIDENCE OF CARCINOGENICITY--ORGAN/TISSUE (NEOPLASM): | ||||
| MR: NO EVIDENCE | ||||
| FR: NO EVIDENCE | ||||
| MM: CLEAR EVIDENCE | HARDERIAN GLAND: ADENOMA 1/48 14/49 29/50 | |||
| LIVER: ADENOMA 8/50 4/50 19/50 OR CARCINOMA 6/50 13/50 12/50 COMBINED 12/50 17/50 26/50 | ||||
| LUNG: ALVEOLAR/BRONCHIOLAR ADENOMA 3/49 6/50 11/50 OR ALVEOLAR/BRONCHIOLAR CARCINOMA 2/49 4/50 10/50 COMBINED 5/49 10/50 18/50 | ||||
| FM: CLEAR EVIDENCE | HARDERIAN GLAND: ADENOMA 5/47 8/45 20/48 | |||
| LIVER: ADENOMA 3/50 4/50 17/49 | ||||
| LUNG: ALVEOLAR/BRONCHIOLAR ADENOMA 4/50 4/50 7/49 OR ALVEOLAR/BRONCHIOLAR CARCINOMA 2/50 5/50 7/49 COMBINED 6/50 8/50 13/49 | ||||
| OVARY: GRANULOSA CELL TUMOR 0/50 5/45 5/47 | ||||
| NON-NEOPLASTIC LESIONS: | OVARY: ATROPHY 3/50 39/45 38/47 | |||
Web page last updated on February 10, 2006
