Summaries & Associations of Study Results
TR-348 Methyldopa Sesquihydrate
Target Organs and Levels of Evidence
NTP Technical Report Number 348
Produced from Chemtrack Database 09/19/01
| CHEMICAL/ CAS NUMBER | PEER REVIEW DATE | PRIMARY USES | ROUTE/EXPOSURE LEVELS | STUDY LABORATORY |
|---|---|---|---|---|
| METHYLDOPA SESQUIHYDRATE 41372-08-1 |
11/06/87 | ANTIHYPERTENSIVE AGENT | Dosed-Feed R: 0, 3100, 6300, M: 0, 6300, 12500 PPM/50 PER GROUP | Physiological Research Laboratory |
| LEVELS OF EVIDENCE OF CARCINOGENICITY--ORGAN/TISSUE (NEOPLASM): | ||||
| MR: NO EVIDENCE | ||||
| FR: NO EVIDENCE | ||||
| MM: EQUIVOCAL EVIDENCE | KIDNEY TUBULAR CELL: ADENOMA 0/50 2/50 0/50 OR ADENOCARCINOMA 0/50 0/50 1/50 COMBINED 0/50 2/50 1/50 | |||
| FM: NO EVIDENCE | ||||
| NON-NEOPLASTIC LESIONS: | KIDNEY: CYSTS 2/50 10/50 10/50; NEPHROPATHY 3/50 21/50 32/50; KARYOMEGALY 0/50 46/50 44/50 | |||
Web page last updated on February 10, 2006
