Summaries & Associations of Study Results
TR-333 N-Phenyl-2-Naphthylamine
Target Organs and Levels of Evidence
NTP Technical Report Number 333
Produced from Chemtrack Database 09/19/01
| CHEMICAL/ CAS NUMBER | PEER REVIEW DATE | PRIMARY USES | ROUTE/EXPOSURE LEVELS | STUDY LABORATORY |
|---|---|---|---|---|
| N-PHENYL-2-NAPHTHYLAMINE 135-88-6 |
03/04/87 | RUBBER ANTIOXIDANT. LUBRICANT. CATALYST. IN DYES, SURGICAL PLASTERS. (TDB) | Dosed-Feed 0,2500,5000 PPM/50 PER GROUP | Battelle Columbus Laboratory |
| LEVELS OF EVIDENCE OF CARCINOGENICITY--ORGAN/TISSUE (NEOPLASM): | ||||
| MR: NO EVIDENCE | ||||
| NON-NEOPLASTIC LESIONS: | KIDNEY: CYSTS; INFLAMMATION, CHRONIC; INFLAMMATION, ACUTE SUPPURATIVE | |||
| FR: NO EVIDENCE | ||||
| NON-NEOPLASTIC LESIONS: | KIDNEY: CYSTS; INFLAMMATION, CHRONIC; INFLAMMATION, ACUTE SUPPURATIVE; MINERALIZATION; NECROSIS; CALCULI; HYPERPLASIA; HYDRONEPHROSIS; ATROPHY; FIBROSIS | |||
| MM: NO EVIDENCE | ||||
| FM: EQUIVOCAL EVIDENCE | KIDNEY TUBULAR CELL: ADENOMA 0/50 0/50 1/47 OR ADENOCARCINOMA 0/50 0/50 1/50 | |||
| NON-NEOPLASTIC LESIONS: | KIDNEY: KARYOMEGALY; NEPHROPATHY | |||
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