Summaries & Associations of Study Results
TR-323 Dimethyl Methylphosphonate
Target Organs and Levels of Evidence
NTP Technical Report Number 323
Produced from Chemtrack Database 09/19/01
| CHEMICAL/ CAS NUMBER | PEER REVIEW DATE | PRIMARY USES | ROUTE/EXPOSURE LEVELS | STUDY LABORATORY |
|---|---|---|---|---|
| DIMETHYL METHYLPHOSPHONATE 756-79-6 |
08/19/86 | FLAME RETARDANT; SOLVENT; HYDRAULIC FLUID; ANTIFOAM AGENT; PLASTICIZER AND STABILIZER; TEXTILE CONDITIONER AND ANTISTATIC AGENT | Gavage R: 0,500,1000, M: 0,1000,2000 MG/KG/50 PER GROUP | Hazleton Labs, Rockville, Gov't Services, Inc |
| LEVELS OF EVIDENCE OF CARCINOGENICITY--ORGAN/TISSUE (NEOPLASM): | ||||
| MR: SOME EVIDENCE | KIDNEY TUBULAR CELL: ADENOCARCINOMA 0/50 2/50 3/49 | |||
| KIDNEY TRANSITIONAL CELL: PAPILLOMA 0/50 7/50 3/49 | ||||
| MAY HAVE BEEN RELATED: | HEMATOPOIETIC SYSTEM: LEUKEMIA 10/50 11/50 17/50 | |||
| NON-NEOPLASTIC LESIONS: | KIDNEY: HYPERPLASIA, TUBULAR CELL 0/50 8/50 9/49; HYPERPLASIA, EPITHELIAL 0/50 23/50 21/49 | |||
| FR: NO EVIDENCE | ||||
| MM: INADEQUATE STUDY | ||||
| FM: NO EVIDENCE | ||||
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