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Summaries & Associations of Study Results

TR-274 Tris(2-ethylhexyl) phosphate

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http://ntp.niehs.nih.gov/go/8135

Target Organs and Levels of Evidence
NTP Technical Report Number 274

Produced from Chemtrack Database 09/19/01

CHEMICAL/ CAS NUMBER PEER REVIEW DATE PRIMARY USES ROUTE/EXPOSURE LEVELS STUDY LABORATORY
TRIS(2-ETHYLHEXYL)PHOSPHATE
78-42-2 		10/28/83 PLASTICIZER FOR VINYL PLASTIC AND SYNTHETIC RUBBER, FLAME RETARDANT Gavage MR: 0,2000,4000, FR: 0,1000,2000, M: 0,500,1000 MG/KG/50 PER GROUP Litton Bionetics, Inc.
LEVELS OF EVIDENCE OF CARCINOGENICITY--ORGAN/TISSUE (NEOPLASM):
MR: EQUIVOCAL EVIDENCE ADRENAL GLAND MEDULLA: PHEOCHROMOCYTOMA 2/50 9/50 12/50
FR: NO EVIDENCE
MM: NO EVIDENCE
NON-NEOPLASTIC LESIONS: THYROID GLAND: HYPERPLASIA, FOLLICULAR CELL
FM: SOME EVIDENCE LIVER: CARCINOMA 0/48 4/50 7/50
NON-NEOPLASTIC LESIONS: THYROID GLAND: HYPERPLASIA, FOLLICULAR CELL

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