Summaries & Associations of Study Results
TR-267 1,2-Propylene oxide
Target Organs and Levels of Evidence
NTP Technical Report Number 267
Produced from Chemtrack Database 09/19/01
| CHEMICAL/ CAS NUMBER | PEER REVIEW DATE | PRIMARY USES | ROUTE/EXPOSURE LEVELS | STUDY LABORATORY |
|---|---|---|---|---|
| 1,2-PROPYLENE OXIDE 75-56-9 |
06/29/83 | INTERMEDIATE IN PRODUCTION OF POLYETHER POLYOLS; FUMIGANT FOR MEDICAL INSTRUMENTS AND FOOD. | Inhalation 0,200,400 PPM/50 PER GROUP | Battelle Northwest Laboratory |
| LEVELS OF EVIDENCE OF CARCINOGENICITY--ORGAN/TISSUE (NEOPLASM): | ||||
| MR: SOME EVIDENCE | NASAL CAVITY: ADENOMA 0/50 0/50 2/50 | |||
| NON-NEOPLASTIC LESIONS: | NASAL CAVITY: INFLAMMATION, SUPPURATIVE; HYPERPLASIA, EPITHELIAL; METAPLASIA, SQUAMOUS | |||
| FR: SOME EVIDENCE | NASAL CAVITY: ADENOMA 0/50 0/50 3/50 | |||
| NON-NEOPLASTIC LESIONS: | NASAL CAVITY: INFLAMMATION, SUPPURATIVE; HYPERPLASIA, EPITHELIAL; METAPLASIA, SQUAMOUS | |||
| MM: CLEAR EVIDENCE | VASCULAR SYSTEM (NASAL CAVITY): HEMANGIOMA 0/50 0/50 5/50; HEMANGIOSARCOMA 0/50 0/50 5/50 | |||
| NON-NEOPLASTIC LESIONS: | NASAL CAVITY: INFLAMMATION, SUPPURATIVE | |||
| FM: CLEAR EVIDENCE | VASCULAR SYSTEM (NASAL CAVITY): HEMANGIOMA 0/50 0/50 3/50; HEMANGIOSARCOMA 0/50 0/50 2/50 | |||
| NON-NEOPLASTIC LESIONS: | NASAL CAVITY: INFLAMMATION, SUPPURATIVE | |||
Web page last updated on February 10, 2006
