Summaries & Associations of Study Results
TR-239 Bis(2-chloro-1- methylethyl) ether
Target Organs and Levels of Evidence
NTP Technical Report Number 239
Produced from Chemtrack Database 09/19/01
| CHEMICAL/ CAS NUMBER | PEER REVIEW DATE | PRIMARY USES | ROUTE/EXPOSURE LEVELS | STUDY LABORATORY |
|---|---|---|---|---|
| BIS(2-CHLORO-1-METHYLETHYL) ETHER 108-60-1 |
12/16/81 | PAINT & VARNISH REMOVERS; INTERMEDIATE IN DYES, RESINS AND PHARMACEUTICALS; NEMATOCIDE IN JAPAN | Gavage 0,100,200 MG/KG/50 PER GROUP | T.S.I. Mason Laboratories, Inc. |
| LEVELS OF EVIDENCE OF CARCINOGENICITY--ORGAN/TISSUE (NEOPLASM): | ||||
| MM: POSITIVE | LUNG: ALVEOLAR/BRONCHIOLAR ADENOMA 5/50 13/50 11/50 | |||
| LIVER: CARCINOMA 5/50 13/50 17/50 | ||||
| FM: POSITIVE | LUNG: ALVEOLAR/BRONCHIOLAR ADENOMA 1/50 4/50 8/50 | |||
| MAY HAVE BEEN RELATED: | FORESTOMACH: SQUAMOUS CELL PAPILLOMA 0/50 0/49 1/49 OR SQUAMOUS CELL CARCINOMA 0/50 0/49 1/49 COMBINED 0/50 0/49 2/49 | |||
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