Summaries & Associations of Study Results
TR-210 1,2-Dibromoethane
Target Organs and Levels of Evidence
NTP Technical Report Number 210
Produced from Chemtrack Database 09/19/01
| CHEMICAL/ CAS NUMBER | PEER REVIEW DATE | PRIMARY USES | ROUTE/EXPOSURE LEVELS | STUDY LABORATORY |
|---|---|---|---|---|
| 1,2-DIBROMOETHANE 106-93-4 |
06/27/80 | SCAVENGER FOR LEAD IN GASOLINE; SOIL AND GRAIN FUMIGANT; INTERMEDIATE FOR DYES AND DRUGS | Inhalation 0,10,40 PPM/50 PER GROUP | Hazleton (Vienna) |
| LEVELS OF EVIDENCE OF CARCINOGENICITY--ORGAN/TISSUE (NEOPLASM): | ||||
| MR: POSITIVE | NASAL CAVITY: ADENOMA 0/50 11/50 0/50; ADENOCARCINOMA 0/50 20/50 28/50; CARCINOMA 0/50 0/50 21/50 | |||
| VASCULAR SYSTEM: HEMANGIOSARCOMA 0/50 1/50 15/50 | ||||
| MESOTHELIUM (ABDOMINAL CAVITY/TUNICA VAGINALIS): MESOTHELIOMA 0/50 7/50 25/50 | ||||
| FR: POSITIVE | NASAL CAVITY: ADENOMA 0/50 11/50 3/50; ADENOCARCINOMA 0/50 20/50 29/50; CARCINOMA 0/50 0/50 25/50 | |||
| VASCULAR SYSTEM: HEMANGIOSARCOMA 0/50 0/50 5/50 | ||||
| MAMMARY GLAND: FIBROADENOMA 4/50 29/50 24/50 | ||||
| LUNG: ALVEOLAR/BRONCHIOLAR ADENOMA 0/50 0/48 1/47 OR ALVEOLAR/BRONCHIOLAR CARCINOMA 0/50 0/48 4/47 COMBINED 0/50 0/48 5/47 | ||||
| MM: POSITIVE | LUNG: ALVEOLAR/BRONCHIOLAR ADENOMA 0/41 0/48 11/46; ALVEOLAR/BRONCHIOLAR CARCINOMA 0/41 3/48 19/46 | |||
| FM: POSITIVE | LUNG: ALVEOLAR/BRONCHIOLAR ADENOMA 3/49 7/49 13/50; ALVEOLAR/BRONCHIOLAR CARCINOMA 1/49 5/49 37/50 | |||
| VASCULAR SYSTEM: HEMANGIOSARCOMA 0/50 11/50 23/50 | ||||
| SUBCUTANEOUS TISSUE: FIBROSARCOMA 0/50 5/50 11/50 | ||||
| NASAL CAVITY: CARCINOMA 0/50 0/50 6/50 | ||||
| MAMMARY GLAND: ADENOCARCINOMA 2/50 14/50 8/50 | ||||
Web page last updated on February 10, 2006
