Summaries & Associations of Study Results
TR-153 o-Toluidine hydrochloride
Target Organs and Levels of Evidence
NTP Technical Report Number 153
Produced from Chemtrack Database 09/19/01
| CHEMICAL/ CAS NUMBER | PEER REVIEW DATE | PRIMARY USES | ROUTE/EXPOSURE LEVELS | STUDY LABORATORY |
|---|---|---|---|---|
| O-TOLUIDINE HYDROCHLORIDE 636-21-5 |
10/25/78 | DYE INTERMEDIATE; PHOTOGRAPHIC DYE; LAB REAGENT; RUBBER MANUFACTURE | Dosed-Feed R: 0,3000,6000, M: 0,1000,3000 PPM/50 PER GROUP | Frederick Cancer Research Facility |
| LEVELS OF EVIDENCE OF CARCINOGENICITY--ORGAN/TISSUE (NEOPLASM): | ||||
| MR: POSITIVE | SPLEEN (SARCOMA) | |||
| MESOTHELIUM (ABDOMINAL CAVITY/TUNICA VAGINALIS): MESOTHELIOMA | ||||
| SUBCUTANEOUS TISSUE (FIBROMA) | ||||
| FR: POSITIVE | SPLEEN (SARCOMA) | |||
| URINARY BLADDER (TRANSITIONAL CELL CARCINOMA) | ||||
| MAMMARY GLAND (ADENOMA OR FIBROADENOMA) | ||||
| MM: POSITIVE | VASCULAR SYSTEM: HEMANGIOSARCOMA | |||
| FM: POSITIVE | LIVER (ADENOMA OR CARCINOMA) | |||
Web page last updated on February 10, 2006
