Summaries & Associations of Study Results
TR-063 4-Chloro-o-phenylenediamine
Target Organs and Levels of Evidence
NTP Technical Report Number 063
Produced from Chemtrack Database 09/19/01
| CHEMICAL/ CAS NUMBER | PEER REVIEW DATE | PRIMARY USES | ROUTE/EXPOSURE LEVELS | STUDY LABORATORY |
|---|---|---|---|---|
| 4-CHLORO-O-PHENYLENEDIAMINE 95-83-0 |
03/06/78 | OXIDATION BASE; CHEMICAL INTERMEDIATE FOR DYES; (FORMERLY) INGREDIENT IN HAIR DYES; CURING AGENT IN EPOXY RESINS (HSDB) | Dosed-Feed R: 0,.5,1.0 (AVG), M: 0,.7,1.4 (AVG) %DIET/50 PER GROUP | T.S.I. Mason Laboratories, Inc. |
| LEVELS OF EVIDENCE OF CARCINOGENICITY--ORGAN/TISSUE (NEOPLASM): | ||||
| MR: POSITIVE | URINARY BLADDER (TRANSITIONAL CELL PAPILLOMA, TRANSITIONAL CELL CARCINOMA) | |||
| FORESTOMACH (SQUAMOUS CELL PAPILLOMA OR SQUAMOUS CELL CARCINOMA) | ||||
| FR: POSITIVE | URINARY BLADDER (TRANSITIONAL CELL PAPILLOMA, TRANSITIONAL CELL CARCINOMA) | |||
| FORESTOMACH (SQUAMOUS CELL PAPILLOMA OR SQUAMOUS CELL CARCINOMA) | ||||
| MM: POSITIVE | LIVER (CARCINOMA) | |||
| FM: POSITIVE | LIVER (CARCINOMA) | |||
Web page last updated on February 10, 2006
