Summaries & Associations of Study Results
TR-058 Tris(aziridinyl)-phosphine sulfide (Thio-TEPA)
Target Organs and Levels of Evidence
NTP Technical Report Number 058
Produced from Chemtrack Database 09/19/01
| CHEMICAL/ CAS NUMBER | PEER REVIEW DATE | PRIMARY USES | ROUTE/EXPOSURE LEVELS | STUDY LABORATORY |
|---|---|---|---|---|
| TRIS(AZIRIDINYL)-PHOSPHINE SULFIDE (THIO-TEPA) 52-24-4 |
04/26/78 | TREATMENT OF MEGALOBLASTIC ANEMIA. POULTRY FEED SUPPLEMENT. IN FOODS & BEVERAGES. | Intraperitoneal Injection R: 0,.7,1.4,2.8, M: 0,1.15,2.3 MG/KG/35 PER GROUP | Southern Research Institute |
| LEVELS OF EVIDENCE OF CARCINOGENICITY--ORGAN/TISSUE (NEOPLASM): | ||||
| MR: POSITIVE | HEMATOPOIETIC SYSTEM (LYMPHOMA OR LEUKEMIA) | |||
| ZYMBAL GLAND (SQUAMOUS CELL CARCINOMA) | ||||
| SKIN (SQUAMOUS CELL CARCINOMA) | ||||
| FR: POSITIVE | ZYMBAL GLAND (SQUAMOUS CELL CARCINOMA) | |||
| SKIN (SQUAMOUS CELL CARCINOMA) | ||||
| MM: POSITIVE | HEMATOPOIETIC SYSTEM (LYMPHOMA, LEUKEMIA) | |||
| SKIN (SQUAMOUS CELL CARCINOMA) | ||||
| PREPUTIAL GLAND (SQUAMOUS CELL CARCINOMA) | ||||
| FM: POSITIVE | HEMATOPOIETIC SYSTEM (LYMPHOMA, LEUKEMIA) | |||
Web page last updated on February 10, 2006
