Summaries & Associations of Study Results
TR-055 1,2-Dichloroethane
Target Organs and Levels of Evidence
NTP Technical Report Number 055
Produced from Chemtrack Database 09/19/01
| CHEMICAL/ CAS NUMBER | PEER REVIEW DATE | PRIMARY USES | ROUTE/EXPOSURE LEVELS | STUDY LABORATORY |
|---|---|---|---|---|
| 1,2-DICHLOROETHANE 107-06-2 |
03/06/78 | PRODUCTION OF VINYL CHLORIDE AND OTHER CHLORINATED CHEMICALS; LEAD SCAVENGER; FUMIGANT; SOLVENT FOR PHARMACEUTICAL PRODUCTS, UPHOLSTERY AND CARPET CLEANER, RUBBER GOODS (HSDB 1990) | Gavage R: 0,47,95 (AVG), MM: 0,97,195 (AVG), FM: 0,149,299 (AVG) MG/KG/50 PER GROUP | Hazleton (Vienna) |
| LEVELS OF EVIDENCE OF CARCINOGENICITY--ORGAN/TISSUE (NEOPLASM): | ||||
| MR: POSITIVE | FORESTOMACH (SQUAMOUS CELL CARCINOMA) | |||
| VASCULAR SYSTEM: (HEMANGIOSARCOMA) | ||||
| SUBCUTANEOUS TISSUE (FIBROMA) | ||||
| FR: POSITIVE | MAMMARY GLAND (ADENOCARCINOMA) | |||
| MM: POSITIVE | LUNG (ALVEOLAR/BRONCHIOLAR ADENOMA) | |||
| FM: POSITIVE | LUNG (ALVEOLAR/BRONCHIOLAR ADENOMA) | |||
| MAMMARY GLAND (ADENOCARCINOMA) | ||||
| UTERUS/CERVIX (POLYP, SARCOMA) | ||||
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