14-3-3s are abundant, dimeric adaptor molecules that are involved in a wide variety of biological processes. They bind other proteins in a phosphorylation-dependent manner (i.e., the binding partner needs to be phosphorylated), and the binding modulates the function of the binding partner. The structure shown above is the first example of a structurally characterized complex between 14-3-3 and a bona-fide enzymatically active molecule.
The green dimer on the bottom is 14-3-3, and the two white molecules on the top are the two phosphorylated serotonin N-acetyltransferase molecules. It is interesting to zoom in to the region of interaction between the molecules.