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New Research to Help People with Mental Disorders Quit Smoking
April 4, 2008 • Science Update
A new grant funded by NIMH will develop an intervention designed to help people with serious mental illness (SMI) quit smoking.
Paying More for Prescriptions May Limit Seniors’ Access to Antidepressants
April 2, 2008 • Science Update
New cost-sharing policies may prevent some older adults diagnosed with depression from filling new antidepressant prescriptions.
Newly Awarded Autism Centers of Excellence to Further Autism Research
April 1, 2008 • Press Release
The National Institutes of Health (NIH) announced on March 24, 2008, the latest recipients of the Autism Centers of Excellence (ACE) program. These grants will support studies covering a broad range of autism research areas, including early brain development and functioning, social interactions in infants, rare genetic variants and mutations, associations between autism-related genes and physical traits, possible environmental risk factors and biomarkers, and a potential new medication treatment.
Rates of Rare Mutations Soar Three to Four Times Higher in Schizophrenia
March 27, 2008 • Press Release
People with schizophrenia have high rates of rare genetic deletions and duplications that likely disrupt the developing brain, according to studies funded in part by the National Institutes of Health.
Autism Gene Scans Converge on Two Suspect Sites, Two Types of Genetic Risk
March 19, 2008 • Science Update
Four teams of scientists, using resources supported in part by NIMH, have pinpointed two different sites in the genome, each conferring a different type of genetic risk for autism.
Past Child Abuse Plus Variations in Gene Result in Potent PTSD Risk for Adults
March 18, 2008 • Press Release
A traumatic event is much more likely to result in posttraumatic stress disorder (PTSD) in adults who experienced trauma in childhood – but certain gene variations raise the risk considerably if the childhood trauma involved physical or sexual abuse, scientists have found.
State Survey Finds FDA “Black Box” Warning Correlates with Curtailed Antidepressant Prescriptions
March 14, 2008 • Science Update
After the U.S. Food and Drug Administration (FDA) issued a “black box” warning on antidepressant medications, Nebraskan doctors began prescribing fewer antidepressant medications to children and teens and referring more patients to specialists, according to a state survey.
One Gene Overrides Another to Prevent Brain Changes that Foster Depression
March 12, 2008 • Science Update
A variation on one gene affects how much of the brain chemical serotonin is available to brain cells. This variation is thought to raise the risk of depression in people who carry it. But NIMH scientists found that a variation in another gene, which produces brain-derived neurotrophic factor (BDNF) – a substance that enables growth and health of brain cells – appears to prevent or offset the changes generated by the depression-fostering variant.
Bipolar Youths’ Misreading of Faces May be Risk Marker for Illness
March 4, 2008 • Science Update
Youngsters with pediatric bipolar disorder and healthy peers who have first-degree relatives with bipolar disorder share the same difficulty labeling facial emotions, NIMH researchers have discovered.
Teens with Treatment-resistant Depression More Likely to Get Better with Switch to Combination Therapy
February 26, 2008 • Press Release
Teens with difficult-to-treat depression who do not respond to a first antidepressant medication are more likely to get well if they switch to another antidepressant medication and add psychotherapy rather than just switching to another antidepressant.
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