| | Guidelines and Guidance The Use of Nonhuman Primate Models in HIV Vaccine Development Cecilia Morgan, Marta Marthas, Christopher Miller, Ann Duerr, Cecilia Cheng-Mayer, Ronald Desrosiers, Jorge Flores, Nancy Haigwood, Shiu-Lok Hu, R. Paul Johnson, Jeffrey Lifson, David Montefiori, John Moore, Marjorie Robert-Guroff, Harriet Robinson, Steven Self, and Lawrence Corey PMCID: PMC2504486 Editorial A Crucial Role for Surgery in Reaching the UN Millennium Development Goals The PLoS Medicine Editors PMCID: PMC2522259 Essay Ensuring the Involvement of Children in the Evaluation of New Tuberculosis Treatment Regimens William J Burman, Mark F Cotton, Diana M Gibb, A. Sarah Walker, Andrew A Vernon, and Peter R Donald PMCID: PMC2517617 Neglected Diseases Strategies to Reduce Mortality from Bacterial Sepsis in Adults in Developing Countries Allen C Cheng, T. Eoin West, Direk Limmathurotsakul, and Sharon J Peacock PMCID: PMC2517616 Perspectives Can a Topical Microbicide Prevent Rectal HIV Transmission? Florian Hladik and Charlene S Dezzutti PMCID: PMC2494564 Developing a Prognostic Model for Traumatic Brain Injury—A Missed Opportunity? Neil H Young and Peter J. D Andrews PMCID: PMC2494565 Children Are Not Just Small Adults: The Urgent Need for High-Quality Trial Evidence in Children Terry P Klassen, Lisa Hartling, Jonathan C Craig, and Martin Offringa PMCID: PMC2504487 More Evidence Against a Causal Association between C-Reactive Protein and Diabetes Bernard Keavney PMCID: PMC2504485 Policy Forum Assessing Antimalarial Efficacy in a Time of Change to Artemisinin-Based Combination Therapies: The Role of Médecins Sans Frontières Jean-Paul Guthmann, Francesco Checchi, Ingrid van den Broek, Suna Balkan, Michel van Herp, Eric Comte, Oscar Bernal, Jean-Marie Kindermans, Sarah Venis, Dominique Legros, and Philippe J Guerin PMCID: PMC2494566 Research in Translation Mendelian Randomisation and Causal Inference in Observational Epidemiology Nuala A Sheehan, Vanessa Didelez, Paul R Burton, and Martin D Tobin PMCID: PMC2522255 Learning Forum An Acute Evolving Flaccid Quadriparesis in an Elderly Woman Rebecca Lim, Sivakumar Sathasivam, and Andrew J Larner PMCID: PMC2522257 Research Articles Inflammation, Insulin Resistance, and Diabetes—Mendelian Randomization Using CRP Haplotypes Points Upstream Eric J Brunner, Mika Kivimäki, Daniel R Witte, Debbie A Lawlor, George Davey Smith, Jackie A Cooper, Michelle Miller, Gordon D. O Lowe, Ann Rumley, Juan P Casas, Tina Shah, Steve E Humphries, Aroon D Hingorani, Michael G Marmot, Nicholas J Timpson, and Meena Kumari PMCID: PMC2504484 Prevention of SIV Rectal Transmission and Priming of T Cell Responses in Macaques after Local Pre-exposure Application of Tenofovir Gel Martin Cranage, Sally Sharpe, Carolina Herrera, Alethea Cope, Mike Dennis, Neil Berry, Claire Ham, Jonathan Heeney, Naser Rezk, Angela Kashuba, Peter Anton, Ian McGowan, and Robin Shattock PMCID: PMC2494562 Predicting Outcome after Traumatic Brain Injury: Development and International Validation of Prognostic Scores Based on Admission Characteristics Ewout W Steyerberg, Nino Mushkudiani, Pablo Perel, Isabella Butcher, Juan Lu, Gillian S McHugh, Gordon D Murray, Anthony Marmarou, Ian Roberts, J. Dik F Habbema, and Andrew I. R Maas PMCID: PMC2494563 Greater Response to Placebo in Children Than in Adults: A Systematic Review and Meta-Analysis in Drug-Resistant Partial Epilepsy Sylvain Rheims, Michel Cucherat, Alexis Arzimanoglou, and Philippe Ryvlin PMCID: PMC2504483 Cancer Screening: A Mathematical Model Relating Secreted Blood Biomarker Levels to Tumor Sizes Amelie M Lutz, Juergen K Willmann, Frank V Cochran, Pritha Ray, and Sanjiv S Gambhir PMCID: PMC2517618 Two Faces of Chondroitin Sulfate Proteoglycan in Spinal Cord Repair: A Role in Microglia/Macrophage Activation Asya Rolls, Ravid Shechter, Anat London, Yifat Segev, Jasmin Jacob-Hirsch, Ninette Amariglio, Gidon Rechavi, and Michal Schwartz PMCID: PMC2517615 Effect of the California Tobacco Control Program on Personal Health Care Expenditures James M Lightwood, Alexis Dinno, and Stanton A Glantz PMCID: PMC2522256 Correction Correction: Diabetes Mellitus Increases the Risk of Active Tuberculosis: A Systematic Review of 13 Observational Studies Christie Y Jeon and Megan B Murray PMCID: PMC2522258 Corrects: Christie Y Jeon, et al. Diabetes Mellitus Increases the Risk of Active Tuberculosis: A Systematic Review of 13 Observational Studies. PLoS Med. 2008 July; 5(7): e152. |
