| | The PLoS Medicine Debate When Should Children with HIV Infection Be Started on Antiretroviral Therapy? Steven B Welch and Di Gibb PMCID: PMC2270305 Editorial It's the Network, Stupid: Why Everything in Medicine Is Connected The PLoS Medicine Editors PMCID: PMC2270303 Essays Could an Open-Source Clinical Trial Data-Management System Be What We Have All Been Looking For? Greg W Fegan and Trudie A Lang PMCID: PMC2267809 Late-Life Cardiac Interventions and the Treatment Imperative Janet K Shim, Ann J Russ, and Sharon R Kaufman PMCID: PMC2270285 Observational Research, Randomised Trials, and Two Views of Medical Science Jan P Vandenbroucke PMCID: PMC2265762 Perspectives Further Evidence that Exclusive Breast-Feeding Reduces Mother-to-Child HIV Transmission Compared With Mixed Feeding Mary Glenn Fowler PMCID: PMC2265760 Determining Origins and Causes of Childhood Obesity via Mendelian Randomization Analysis Eric L Ding and Frank B Hu PMCID: PMC2265761 Inferring HIV Transmission Dynamics from Phylogenetic Sequence Relationships Christopher D Pilcher, Joseph K Wong, and Satish K Pillai PMCID: PMC2267810 The Potential Effect of Statins on Rituximab Immunotherapy Mark S Cragg PMCID: PMC2270307 Policy Forum Defining Challenges and Proposing Solutions for Control of the Virus Vector Aedes aegypti Amy C Morrison, Emily Zielinski-Gutierrez, Thomas W Scott, and Ronald Rosenberg PMCID: PMC2267811 Syndromic Surveillance: Adapting Innovations to Developing Settings Jean-Paul Chretien, Howard S Burkom, Endang R Sedyaningsih, Ria P Larasati, Andres G Lescano, Carmen C Mundaca, David L Blazes, Cesar V Munayco, Jacqueline S Coberly, Raj J Ashar, and Sheri H Lewis PMCID: PMC2270304 Research in Translation Idiopathic Pulmonary Fibrosis: Aberrant Recapitulation of Developmental Programs? Moisés Selman, Annie Pardo, and Naftali Kaminski PMCID: PMC2265304 Research Articles Exploring the Developmental Overnutrition Hypothesis Using Parental–Offspring Associations and FTO as an Instrumental Variable Debbie A Lawlor, Nicholas J Timpson, Roger M Harbord, Sam Leary, Andy Ness, Mark I McCarthy, Timothy M Frayling, Andrew T Hattersley, and George Davey Smith PMCID: PMC2265763 An Antibiotic-Responsive Mouse Model of Fulminant Ulcerative Colitis Silvia S Kang, Seth M Bloom, Lyse A Norian, Michael J Geske, Richard A Flavell, Thaddeus S Stappenbeck, and Paul M Allen PMCID: PMC2270287 Episodic Sexual Transmission of HIV Revealed by Molecular Phylodynamics Fraser Lewis, Gareth J Hughes, Andrew Rambaut, Anton Pozniak, and Andrew J. Leigh Brown PMCID: PMC2267814 Global Transcript Profiles of Fat in Monozygotic Twins Discordant for BMI: Pathways behind Acquired Obesity Kirsi H Pietiläinen, Jussi Naukkarinen, Aila Rissanen, Juha Saharinen, Pekka Ellonen, Heli Keränen, Anu Suomalainen, Alexandra Götz, Tapani Suortti, Hannele Yki-Järvinen, Matej Orešič, Jaakko Kaprio, and Leena Peltonen PMCID: PMC2265758 Alcohol Intake and Blood Pressure: A Systematic Review Implementing a Mendelian Randomization Approach Lina Chen, George Davey Smith, Roger M Harbord, and Sarah J Lewis PMCID: PMC2265305 The Impact of Monitoring HIV Patients Prior to Treatment in Resource-Poor Settings: Insights from Mathematical Modelling Timothy B Hallett, Simon Gregson, Sabada Dube, and Geoff P Garnett PMCID: PMC2265759 Aberrant Mucin Assembly in Mice Causes Endoplasmic Reticulum Stress and Spontaneous Inflammation Resembling Ulcerative Colitis Chad K Heazlewood, Matthew C Cook, Rajaraman Eri, Gareth R Price, Sharyn B Tauro, Douglas Taupin, David J Thornton, Chin Wen Png, Tanya L Crockford, Richard J Cornall, Rachel Adams, Masato Kato, Keats A Nelms, Nancy A Hong, Timothy H. J Florin, Christopher C Goodnow, and Michael A McGuckin PMCID: PMC2270292 Increased Microerythrocyte Count in Homozygous α+-Thalassaemia Contributes to Protection against Severe Malarial Anaemia Freya J. I Fowkes, Stephen J Allen, Angela Allen, Michael P Alpers, David J Weatherall, and Karen P Day PMCID: PMC2267813 Multidisciplinary Prospective Study of Mother-to-Child Chikungunya Virus Infections on the Island of La Réunion Patrick Gérardin, Georges Barau, Alain Michault, Marc Bintner, Hanitra Randrianaivo, Ghassan Choker, Yann Lenglet, Yasmina Touret, Anne Bouveret, Philippe Grivard, Karin Le Roux, Séverine Blanc, Isabelle Schuffenecker, Thérèse Couderc, Fernando Arenzana-Seisdedos, Marc Lecuit, and Pierre-Yves Robillard PMCID: PMC2267812 Statins Impair Antitumor Effects of Rituximab by Inducing Conformational Changes of CD20 Magdalena Winiarska, Jacek Bil, Ewa Wilczek, Grzegorz M Wilczynski, Malgorzata Lekka, Patrick J Engelberts, Wendy J. M Mackus, Elzbieta Gorska, Lukasz Bojarski, Tomasz Stoklosa, Dominika Nowis, Zuzanna Kurzaj, Marcin Makowski, Eliza Glodkowska, Tadeusz Issat, Piotr Mrowka, Witold Lasek, Anna Dabrowska-Iwanicka, Grzegorz W Basak, Maria Wasik, Krzysztof Warzocha, Maciej Sinski, Zbigniew Gaciong, Marek Jakobisiak, Paul W. H. I Parren, and Jakub Golab PMCID: PMC2270297 Social Contacts and Mixing Patterns Relevant to the Spread of Infectious Diseases Joël Mossong, Niel Hens, Mark Jit, Philippe Beutels, Kari Auranen, Rafael Mikolajczyk, Marco Massari, Stefania Salmaso, Gianpaolo Scalia Tomba, Jacco Wallinga, Janneke Heijne, Malgorzata Sadkowska-Todys, Magdalena Rosinska, and W. John Edmunds PMCID: PMC2270306 Correction Correction: Combined Impact of Health Behaviours and Mortality in Men and Women: The EPIC-Norfolk Prospective Population Study Kay-Tee Khaw, Nicholas Wareham, Sheila Bingham, Ailsa Welch, Robert Luben, and Nicholas Day PMCID: PMC2270302 Corrects: Kay-Tee Khaw, et al. Combined Impact of Health Behaviours and Mortality in Men and Women: The EPIC-Norfolk Prospective Population Study. PLoS Med. 2008 January; 5(1): e12. |
