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Volume 3(12);  December 2006
Correspondence
Enrolling Adolescents in Research on HIV: Young Women Must Be Included
Alana de Kock, Stephanie Skoler, Khatija Ahmed, and Sumen Govender
PLoS Med. 2006 December; 3(12): e537. Published online 2006 December 26. doi: 10.1371/journal.pmed.0030537.
PMCID: PMC1762084
HIV-1 Viral Load Assays for Resource-Limited Settings: Clades Matter
Wolfgang Preiser, Jan Felix Drexler, and Christian Drosten
PLoS Med. 2006 December; 3(12): e538. Published online 2006 December 26. doi: 10.1371/journal.pmed.0030538.
PMCID: PMC1762044
Multidrug-Resistant TB in the Philippines: Totem and Taboo
Jose Luis Portero and Maria Rubio
PLoS Med. 2006 December; 3(12): e539. Published online 2006 December 26. doi: 10.1371/journal.pmed.0030539.
PMCID: PMC1762047
HIV-1 Subtype and Reverse Transcriptase Genotype: Role for Geographical Location and Founder Effects
Akinyemi I Ojesina and Phyllis J Kanki
PLoS Med. 2006 December; 3(12): e540. Published online 2006 December 26. doi: 10.1371/journal.pmed.0030540.
PMCID: PMC1762043
Reassurance: Medically Unexplained Physical Symptoms
Bill Anderson
PLoS Med. 2006 December; 3(12): e541. Published online 2006 December 26. doi: 10.1371/journal.pmed.0030541.
PMCID: PMC1762046
Cost-Effective Control of Drug-Resistant TB: Listening to Other Voices
Jose Luis Portero and Maria Rubio
PLoS Med. 2006 December; 3(12): e542. Published online 2006 December 26. doi: 10.1371/journal.pmed.0030542.
PMCID: PMC1762049
Multidrug-Resistant TB in the Philippines: Authors' Reply
Thelma Tupasi
PLoS Med. 2006 December; 3(12): e549. Published online 2006 December 26. doi: 10.1371/journal.pmed.0030549.
PMCID: PMC1762076
HIV-1 Viral Load Assays for Resource-Limited Settings: Authors' Reply
Susan A Fiscus
PLoS Med. 2006 December; 3(12): e550. Published online 2006 December 26. doi: 10.1371/journal.pmed.0030550.
PMCID: PMC1762069
Editorial
Drug Development Papers in PLoS Medicine: How We Try to Spot a Winner
The PLoS Medicine Editors and Sanjeev Krishna
PLoS Med. 2006 December; 3(12): e547. Published online 2006 December 26. doi: 10.1371/journal.pmed.0030547.
PMCID: PMC1762067
Essays
Intensive Insulin Therapy in Intensive Care: An Example of the Struggle to Implement Evidence-Based Medicine
Marcus J Schultz, Annick A. N. M Royakkers, Marcel Levi, Hazra S Moeniralam, and Peter E Spronk
PLoS Med. 2006 December; 3(12): e456. Published online 2006 December 5. doi: 10.1371/journal.pmed.0030456.
PMCID: PMC1762062
Do We Need a World Health Insurance to Realise the Right to Health?
Gorik Ooms, Katharine Derderian, and David Melody
PLoS Med. 2006 December; 3(12): e530. Published online 2006 December 26. doi: 10.1371/journal.pmed.0030530.
PMCID: PMC1762058
Perspectives
Visual Loss in Postconflict Southern Sudan
John Buchan
PLoS Med. 2006 December; 3(12): e450. Published online 2006 December 19. doi: 10.1371/journal.pmed.0030450.
PMCID: PMC1698938
Blindness in Sudan: Is It Time to Scrutinise Survey Methods?
Hannah Kuper and Clare Gilbert
PLoS Med. 2006 December; 3(12): e476. Published online 2006 December 19. doi: 10.1371/journal.pmed.0030476.
PMCID: PMC1698939
Mining Methylation for Early Detection of Common Cancers
Romulo M Brena, Christoph Plass, and Joseph F Costello
PLoS Med. 2006 December; 3(12): e479. Published online 2006 December 26. doi: 10.1371/journal.pmed.0030479.
PMCID: PMC1762083
TV and Inactivity Are Separate Contributors to Metabolic Risk Factors in Children
Andrew Prentice and Susan Jebb
PLoS Med. 2006 December; 3(12): e481. Published online 2006 December 12. doi: 10.1371/journal.pmed.0030481.
PMCID: PMC1705823
Stem Cells and Metastatic Cancer: Fatal Attraction?
Riccardo Fodde
PLoS Med. 2006 December; 3(12): e482. Published online 2006 December 26. doi: 10.1371/journal.pmed.0030482.
PMCID: PMC1762040
Are Residents' Extended Shifts Associated With Adverse Events?
Mariana Szklo-Coxe
PLoS Med. 2006 December; 3(12): e497. Published online 2006 December 12. doi: 10.1371/journal.pmed.0030497.
PMCID: PMC1705827
Antibodies and Brain Disease: A Convergence of Immunology and Physiology
Betty Diamond and Bruce T Volpe
PLoS Med. 2006 December; 3(12): e498. Published online 2006 December 19. doi: 10.1371/journal.pmed.0030498.
PMCID: PMC1698940
Impact of Antiretroviral Therapy on Intestinal Lymphoid Tissues in HIV Infection
Ronald S Veazey and Andrew A Lackner
PLoS Med. 2006 December; 3(12): e515. Published online 2006 December 5. doi: 10.1371/journal.pmed.0030515.
PMCID: PMC1762071
Health in Action
The Malaria Atlas Project: Developing Global Maps of Malaria Risk
Simon I Hay and Robert W Snow
PLoS Med. 2006 December; 3(12): e473. Published online 2006 December 5. doi: 10.1371/journal.pmed.0030473.
PMCID: PMC1762059
Healthy Penis: San Francisco's Social Marketing Campaign to Increase Syphilis Testing among Gay and Bisexual Men
Katherine Ahrens, Charlotte K Kent, Jorge A Montoya, Harlan Rotblatt, Jacque McCright, Peter Kerndt, and Jeffrey D Klausner
PLoS Med. 2006 December; 3(12): e474. Published online 2006 December 26. doi: 10.1371/journal.pmed.0030474.
PMCID: PMC1762065
Learning Forum
Ophthalmoplegia and Slurred Speech in an Intravenous Drug User
Jaime Vera, Anke Hensiek, Charles Woodrow, Francesca Crawley, and Sanjeev Krishna
PLoS Med. 2006 December; 3(12): e453. Published online 2006 December 26. doi: 10.1371/journal.pmed.0030453.
PMCID: PMC1762052
Hypogammaglobulinemia with Facial Edema
Adina Kay Knight, Lloyd Mayer, Andrew G Franks, Jr., and Charlotte Cunningham-Rundles
PLoS Med. 2006 December; 3(12): e475. Published online 2006 December 26. doi: 10.1371/journal.pmed.0030475.
PMCID: PMC1762068
Research Articles
A Gene Expression Signature Predicts Survival of Patients with Stage I Non-Small Cell Lung Cancer
Yan Lu, William Lemon, Peng-Yuan Liu, Yijun Yi, Carl Morrison, Ping Yang, Zhifu Sun, Janos Szoke, William L Gerald, Mark Watson, Ramaswamy Govindan, and Ming You
PLoS Med. 2006 December; 3(12): e467. Published online 2006 December 26. doi: 10.1371/journal.pmed.0030467.
PMCID: PMC1716187
Prevalence and Causes of Blindness and Low Vision in Southern Sudan
Jeremiah Ngondi, Francis Ole-Sempele, Alice Onsarigo, Ibrahim Matende, Samson Baba, Mark Reacher, Fiona Matthews, Carol Brayne, and Paul M Emerson
PLoS Med. 2006 December; 3(12): e477. Published online 2006 December 19. doi: 10.1371/journal.pmed.0030477.
PMCID: PMC1702554
Blinding Trachoma in Postconflict Southern Sudan
Jeremiah Ngondi, Francis Ole-Sempele, Alice Onsarigo, Ibrahim Matende, Samson Baba, Mark Reacher, Fiona Matthews, Carol Brayne, and Paul Emerson
PLoS Med. 2006 December; 3(12): e478. Published online 2006 December 19. doi: 10.1371/journal.pmed.0030478.
PMCID: PMC1702555
Lack of Mucosal Immune Reconstitution during Prolonged Treatment of Acute and Early HIV-1 Infection
Saurabh Mehandru, Michael A Poles, Klara Tenner-Racz, Patrick Jean-Pierre, Victoria Manuelli, Peter Lopez, Anita Shet, Andrea Low, Hiroshi Mohri, Daniel Boden, Paul Racz, and Martin Markowitz
PLoS Med. 2006 December; 3(12): e484. Published online 2006 December 5. doi: 10.1371/journal.pmed.0030484.
PMCID: PMC1762085
Epidermal Growth Factor Receptor Activation in Glioblastoma through Novel Missense Mutations in the Extracellular Domain
Jeffrey C Lee, Igor Vivanco, Rameen Beroukhim, Julie H. Y Huang, Whei L Feng, Ralph M DeBiasi, Koji Yoshimoto, Jennifer C King, Phioanh Nghiemphu, Yuki Yuza, Qing Xu, Heidi Greulich, Roman K Thomas, J. Guillermo Paez, Timothy C Peck, David J Linhart, Karen A Glatt, Gad Getz, Robert Onofrio, Liuda Ziaugra, Ross L Levine, Stacey Gabriel, Tomohiro Kawaguchi, Keith O'Neill, Haumith Khan, Linda M Liau, Stanley F Nelson, P. Nagesh Rao, Paul Mischel, Russell O Pieper, Tim Cloughesy, Daniel J Leahy, William R Sellers, Charles L Sawyers, Matthew Meyerson, and Ingo K Mellinghoff
PLoS Med. 2006 December; 3(12): e485. Published online 2006 December 19. doi: 10.1371/journal.pmed.0030485.
PMCID: PMC1702556
A Genome-Wide Screen for Promoter Methylation in Lung Cancer Identifies Novel Methylation Markers for Multiple Malignancies
David S Shames, Luc Girard, Boning Gao, Mitsuo Sato, Cheryl M Lewis, Narayan Shivapurkar, Aixiang Jiang, Charles M Perou, Young H Kim, Jonathan R Pollack, Kwun M Fong, Chi-Leung Lam, Maria Wong, Yu Shyr, Rita Nanda, Olufunmilayo I Olopade, William Gerald, David M Euhus, Jerry W Shay, Adi F Gazdar, and John D Minna
PLoS Med. 2006 December; 3(12): e486. Published online 2006 December 26. doi: 10.1371/journal.pmed.0030486.
PMCID: PMC1716188
Impact of Extended-Duration Shifts on Medical Errors, Adverse Events, and Attentional Failures
Laura K Barger, Najib T Ayas, Brian E Cade, John W Cronin, Bernard Rosner, Frank E Speizer, and Charles A Czeisler
PLoS Med. 2006 December; 3(12): e487. Published online 2006 December 12. doi: 10.1371/journal.pmed.0030487.
PMCID: PMC1705824
TV Viewing and Physical Activity Are Independently Associated with Metabolic Risk in Children: The European Youth Heart Study
Ulf Ekelund, Søren Brage, Karsten Froberg, Maarike Harro, Sigmund A Anderssen, Luis B Sardinha, Chris Riddoch, and Lars Bo Andersen
PLoS Med. 2006 December; 3(12): e488. Published online 2006 December 12. doi: 10.1371/journal.pmed.0030488.
PMCID: PMC1705825
Elevated Serum Levels of Interferon-Regulated Chemokines Are Biomarkers for Active Human Systemic Lupus Erythematosus
Jason W Bauer, Emily C Baechler, Michelle Petri, Franak M Batliwalla, Dianna Crawford, Ward A Ortmann, Karl J Espe, Wentian Li, Dhavalkumar D Patel, Peter K Gregersen, and Timothy W Behrens
PLoS Med. 2006 December; 3(12): e491. Published online 2006 December 19. doi: 10.1371/journal.pmed.0030491.
PMCID: PMC1702557
Impaired Hepatitis C Virus-Specific T Cell Responses and Recurrent Hepatitis C Virus in HIV Coinfection
Arthur Y Kim, Julian Schulze zur Wiesch, Thomas Kuntzen, Joerg Timm, Daniel E Kaufmann, Jared E Duncan, Andrea M Jones, Alysse G Wurcel, Benjamin T Davis, Rajesh T Gandhi, Gregory K Robbins, Todd M Allen, Raymond T Chung, Georg M Lauer, and Bruce D Walker
PLoS Med. 2006 December; 3(12): e492. Published online 2006 December 12. doi: 10.1371/journal.pmed.0030492.
PMCID: PMC1705826
Hyaluronate Fragments Reverse Skin Atrophy by a CD44-Dependent Mechanism
Gürkan Kaya, Christian Tran, Olivier Sorg, Raymonde Hotz, Denise Grand, Pierre Carraux, Liliane Didierjean, Ivan Stamenkovic, and Jean-Hilaire Saurat
PLoS Med. 2006 December; 3(12): e493. Published online 2006 December 19. doi: 10.1371/journal.pmed.0030493.
PMCID: PMC1702558
Tuberculosis among Health-Care Workers in Low- and Middle-Income Countries: A Systematic Review
Rajnish Joshi, Arthur L Reingold, Dick Menzies, and Madhukar Pai
PLoS Med. 2006 December; 3(12): e494. Published online 2006 December 26. doi: 10.1371/journal.pmed.0030494.
PMCID: PMC1716189
Lipoprotein Particle Profiles Mark Familial and Sporadic Human Longevity
Bastiaan T Heijmans, Marian Beekman, Jeanine J Houwing-Duistermaat, Mark R Cobain, Jonathan Powell, Gerard Jan Blauw, Frans van der Ouderaa, Rudi G. J Westendorp, and P. Eline Slagboom
PLoS Med. 2006 December; 3(12): e495. Published online 2006 December 26. doi: 10.1371/journal.pmed.0030495.
PMCID: PMC1716190
Selective Involvement of the Amygdala in Systemic Lupus Erythematosus
Bart J Emmer, Jeroen van der Grond, Gerda M Steup-Beekman, Tom W. J Huizinga, and Mark A van Buchem
PLoS Med. 2006 December; 3(12): e499. Published online 2006 December 19. doi: 10.1371/journal.pmed.0030499.
PMCID: PMC1702559
Children with Severe Malnutrition: Can Those at Highest Risk of Death Be Identified with the WHO Protocol?
Kathryn Maitland, James A Berkley, Mohammed Shebbe, Norbert Peshu, Michael English, and Charles R. J. C Newton
PLoS Med. 2006 December; 3(12): e500. Published online 2006 December 26. doi: 10.1371/journal.pmed.0030500.
PMCID: PMC1716191
A Plant-Derived Morphinan as a Novel Lead Compound Active against Malaria Liver Stages
Maëlle Carraz, Akino Jossang, Jean-François Franetich, Anthony Siau, Liliane Ciceron, Laurent Hannoun, Robert Sauerwein, François Frappier, Philippe Rasoanaivo, Georges Snounou, and Dominique Mazier
PLoS Med. 2006 December; 3(12): e513. Published online 2006 December 26. doi: 10.1371/journal.pmed.0030513.
PMCID: PMC1716192
Palladin Mutation Causes Familial Pancreatic Cancer and Suggests a New Cancer Mechanism
Kay L Pogue-Geile, Ru Chen, Mary P Bronner, Tatjana Crnogorac-Jurcevic, Kara White Moyes, Sally Dowen, Carol A Otey, David A Crispin, Ryan D George, David C Whitcomb, and Teresa A Brentnall
PLoS Med. 2006 December; 3(12): e516. Published online 2006 December 12. doi: 10.1371/journal.pmed.0030516.
PMCID: PMC1751121
Cost-Effectiveness of Male Circumcision for HIV Prevention in a South African Setting
James G Kahn, Elliot Marseille, and Bertran Auvert
PLoS Med. 2006 December; 3(12): e517. Published online 2006 December 26. doi: 10.1371/journal.pmed.0030517.
PMCID: PMC1716193
Angiotensin-Converting Enzyme I/D Polymorphism and Preeclampsia Risk: Evidence of Small-Study Bias
Norma C Serrano, Luis A Díaz, Maria C Páez, Clara M Mesa, Rodrigo Cifuentes, Alvaro Monterrosa, Adriana González, Liam Smeeth, Aroon D Hingorani, and Juan P Casas
PLoS Med. 2006 December; 3(12): e520. Published online 2006 December 26. doi: 10.1371/journal.pmed.0030520.
PMCID: PMC1716194
Vaccine Efficacy in Senescent Mice Challenged with Recombinant SARS-CoV Bearing Epidemic and Zoonotic Spike Variants
Damon Deming, Timothy Sheahan, Mark Heise, Boyd Yount, Nancy Davis, Amy Sims, Mehul Suthar, Jack Harkema, Alan Whitmore, Raymond Pickles, Ande West, Eric Donaldson, Kristopher Curtis, Robert Johnston, and Ralph Baric
PLoS Med. 2006 December; 3(12): e525. Published online 2006 December 26. doi: 10.1371/journal.pmed.0030525.
PMCID: PMC1716185
Erythrocyte G Protein as a Novel Target for Malarial Chemotherapy
Sean C Murphy, Travis Harrison, Heidi E Hamm, Jon W Lomasney, Narla Mohandas, and Kasturi Haldar
PLoS Med. 2006 December; 3(12): e528. Published online 2006 December 26. doi: 10.1371/journal.pmed.0030528.
PMCID: PMC1716186
Corrections
Correction: Is the Current Management of Severe Sepsis and Septic Shock Really Evidence Based?
Jean-Louis Vincent
PLoS Med. 2006 December; 3(12): e543. Published online 2006 December 26. doi: 10.1371/journal.pmed.0030543.
PMCID: PMC1762053
Corrects: Jean-Louis Vincent. Is the Current Management of Severe Sepsis and Septic Shock Really Evidence Based? PLoS Med. 2006 September; 3(9): e346.
Correction: Eight Americas: Investigating Mortality Disparities across Races, Counties, and Race-Counties in the United States
Christopher J. L Murray, Sandeep C Kulkarni, Catherine Michaud, Niels Tomijima, Maria T Bulzacchelli, Terrell J Iandiorio, and Majid Ezzati
PLoS Med. 2006 December; 3(12): e545. Published online 2006 December 26. doi: 10.1371/journal.pmed.0030545.
PMCID: PMC1762056
Corrects: Christopher J. L Murray, et al. Eight Americas: Investigating Mortality Disparities across Races, Counties, and Race-Counties in the United States. PLoS Med. 2006 September; 3(9): e260.
Correction: Lack of Mucosal Immune Reconstitution during Prolonged Treatment of Acute and Early HIV-1 Infection
Saurabh Mehandru, Michael A Poles, Klara Tenner-Racz, Patrick Jean-Pierre, Victoria Manuelli, Peter Lopez, Anita Shet, Andrea Low, Hiroshi Mohri, Daniel Boden, Paul Racz, and Martin Markowitz
PLoS Med. 2006 December; 3(12): e546. Published online 2006 December 26. doi: 10.1371/journal.pmed.0030546.
PMCID: PMC1762064
Corrects: Saurabh Mehandru, et al. Lack of Mucosal Immune Reconstitution during Prolonged Treatment of Acute and Early HIV-1 Infection. PLoS Med. 2006 December; 3(12): e484.
Other Issues:  previous | next | latest | archive