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Volume 2(9);  September 2005
Editorial
A New Era of Hope for the World's Most Neglected Diseases
The PLoS Medicine Editors
PLoS Med. 2005 September; 2(9): e323. Published online 2005 September 8. doi: 10.1371/journal.pmed.0020323.
PMCID: PMC1198044
Synopses
Type 2 Diabetes: Insulin Resistance May Be the Result of Mitochondrial Dysfunction
PLoS Med. 2005 September; 2(9): e292. Published online 2005 August 16. doi: 10.1371/journal.pmed.0020292.
PMCID: PMC1184228
Role of Osteopontin in Idiopathic Pulmonary Fibrosis
PLoS Med. 2005 September; 2(9): e314. Published online 2005 September 6. doi: 10.1371/journal.pmed.0020314.
PMCID: PMC1198043
Targeting of Endothelial Activation in Cerebral Malaria
PLoS Med. 2005 September; 2(9): e315. Published online 2005 August 23. doi: 10.1371/journal.pmed.0020315.
PMCID: PMC1188257
Getting More Mileage from Lymph Node Biopsies
PLoS Med. 2005 September; 2(9): e324. Published online 2005 September 6. doi: 10.1371/journal.pmed.0020324.
PMCID: PMC1198045
A Tool to Estimate the Risks of Repeat Cesarean Section
PLoS Med. 2005 September; 2(9): e325. Published online 2005 September 13. doi: 10.1371/journal.pmed.0020325.
PMCID: PMC1201367
Is it Possible to Change Prescribing Habits?
PLoS Med. 2005 September; 2(9): e328. Published online 2005 September 6. doi: 10.1371/journal.pmed.0020328.
PMCID: PMC1198046
Essays
The Abandoned Trials of Pre-Exposure Prophylaxis for HIV: What Went Wrong?
Jerome A Singh and Edward J Mills
PLoS Med. 2005 September; 2(9): e234. Published online 2005 July 19. doi: 10.1371/journal.pmed.0020234.
PMCID: PMC1176237
Curbing the Influence of the Drug Industry: A British View
Smith Richard
PLoS Med. 2005 September; 2(9): e241. Published online 2005 August 2. doi: 10.1371/journal.pmed.0020241.
PMCID: PMC1181537
Neglected Diseases
A Breakthrough in R&D for Neglected Diseases: New Ways to Get the Drugs We Need
Mary Moran
PLoS Med. 2005 September; 2(9): e302. Published online 2005 September 8. doi: 10.1371/journal.pmed.0020302.
PMCID: PMC1198042
Perspectives
We Must Not Let Protestors Derail Trials of Pre-Exposure Prophylaxis for HIV
Joep M. A Lange
PLoS Med. 2005 September; 2(9): e248. Published online 2005 July 19. doi: 10.1371/journal.pmed.0020248.
PMCID: PMC1176241
Insulin Resistance in the Offspring of Parents with Type 2 Diabetes
Anton J. M Wagenmakers
PLoS Med. 2005 September; 2(9): e289. Published online 2005 September 27. doi: 10.1371/journal.pmed.0020289.
PMCID: PMC1236795
Computerized Physician Order Entry Systems: The Coming of Age for Outpatient Medicine
Robert L Davis
PLoS Med. 2005 September; 2(9): e290. Published online 2005 September 27. doi: 10.1371/journal.pmed.0020290.
PMCID: PMC1236796
Does the Maxim “Once a Caesarean, Always a Caesarean” Still Hold True?
Austin Ugwumadu
PLoS Med. 2005 September; 2(9): e305. Published online 2005 September 27. doi: 10.1371/journal.pmed.0020305.
PMCID: PMC1236800
Health in Action
Using Search Engines to Find Online Medical Information
Mohammad Al-Ubaydli
PLoS Med. 2005 September; 2(9): e228. Published online 2005 August 2. doi: 10.1371/journal.pmed.0020228.
PMCID: PMC1181536
The European Rare Diseases Therapeutic Initiative
Alain Fischer, Pascale Borensztein, and Claire Roussel
PLoS Med. 2005 September; 2(9): e243. Published online 2005 August 23. doi: 10.1371/journal.pmed.0020243.
PMCID: PMC1188253
Policy Forum
What Can We Do to Improve Child Health in Southern Italy?
Maurizio Bonati and Rita Campi
PLoS Med. 2005 September; 2(9): e250. Published online 2005 August 23. doi: 10.1371/journal.pmed.0020250.
PMCID: PMC1188255
Deception in Research on the Placebo Effect
Franklin G Miller, David Wendler, and Leora C Swartzman
PLoS Med. 2005 September; 2(9): e262. Published online 2005 September 6. doi: 10.1371/journal.pmed.0020262.
PMCID: PMC1198039
Research in Translation
Will Nicotine Genetics and a Nicotine Vaccine Prevent Cigarette Smoking and Smoking-Related Diseases?
Wayne D Hall
PLoS Med. 2005 September; 2(9): e266. Published online 2005 September 27. doi: 10.1371/journal.pmed.0020266.
PMCID: PMC1236791
Research Articles
Decreased Insulin-Stimulated ATP Synthesis and Phosphate Transport in Muscle of Insulin-Resistant Offspring of Type 2 Diabetic Parents
Kitt F Petersen, Sylvie Dufour, and Gerald I Shulman
PLoS Med. 2005 September; 2(9): e233. Published online 2005 August 16. doi: 10.1371/journal.pmed.0020233.
PMCID: PMC1184227
Inhibition of Endothelial Activation: A New Way to Treat Cerebral Malaria?
Samuel C Wassmer, George J Cianciolo, Valéry Combes, and Georges E Grau
PLoS Med. 2005 September; 2(9): e245. Published online 2005 August 23. doi: 10.1371/journal.pmed.0020245.
PMCID: PMC1188254
Up-Regulation and Profibrotic Role of Osteopontin in Human Idiopathic Pulmonary Fibrosis
Annie Pardo, Kevin Gibson, José Cisneros, Thomas J Richards, Yinke Yang, Carina Becerril, Samueal Yousem, Iliana Herrera, Victor Ruiz, Moisés Selman, and Naftali Kaminski
PLoS Med. 2005 September; 2(9): e251. Published online 2005 September 6. doi: 10.1371/journal.pmed.0020251.
PMCID: PMC1198037
Predicting Cesarean Section and Uterine Rupture among Women Attempting Vaginal Birth after Prior Cesarean Section
Gordon C. S Smith, Ian R White, Jill P Pell, and Richard Dobbie
PLoS Med. 2005 September; 2(9): e252. Published online 2005 September 13. doi: 10.1371/journal.pmed.0020252.
PMCID: PMC1201366
The Effect of Automated Alerts on Provider Ordering Behavior in an Outpatient Setting
Andrew W Steele, Sheri Eisert, Joel Witter, Pat Lyons, Michael A Jones, Patricia Gabow, and Eduardo Ortiz
PLoS Med. 2005 September; 2(9): e255. Published online 2005 September 6. doi: 10.1371/journal.pmed.0020255.
PMCID: PMC1198038
Profile of Immune Cells in Axillary Lymph Nodes Predicts Disease-Free Survival in Breast Cancer
Holbrook E Kohrt, Navid Nouri, Kent Nowels, Denise Johnson, Susan Holmes, and Peter P Lee
PLoS Med. 2005 September; 2(9): e284. Published online 2005 September 6. doi: 10.1371/journal.pmed.0020284.
PMCID: PMC1198041
Correspondence and Other Communications
Acquired Gefitinib-Resistant Mutation of EGFR in a Chemonaive Lung Adenocarcinoma Harboring Gefitinib-Sensitive Mutation L858R
Chien-Hung Gow, Jin-Yuan Shih, Yih-Leong Chang, and Chong-Jen Yu
PLoS Med. 2005 September; 2(9): e269. Published online 2005 September 27. doi: 10.1371/journal.pmed.0020269.
PMCID: PMC1236792
Secondary Schizophrenia
Dave Hambidge
PLoS Med. 2005 September; 2(9): e279. Published online 2005 September 27. doi: 10.1371/journal.pmed.0020279.
PMCID: PMC1236793
Authors' Reply: Measurement Errors in Schizophrenia Epidemiology
John McGrath, Sukanta Saha, Joy Welham, and David Charles Chant
PLoS Med. 2005 September; 2(9): e300. Published online 2005 September 27. doi: 10.1371/journal.pmed.0020300.
PMCID: PMC1236798
Misleading Information on the Properties of Vitamin C
Steve Hickey and Hilary Roberts
PLoS Med. 2005 September; 2(9): e307. Published online 2005 September 27. doi: 10.1371/journal.pmed.0020307.
PMCID: PMC1236801
Narrow Scope of Vitamin C Review
William Sardi
PLoS Med. 2005 September; 2(9): e308. Published online 2005 September 27. doi: 10.1371/journal.pmed.0020308.
PMCID: PMC1236802
Authors' Reply
Harri Hemilä and Robert M Douglas
PLoS Med. 2005 September; 2(9): e309. Published online 2005 September 27. doi: 10.1371/journal.pmed.0020309.
PMCID: PMC1236803
Tamoxifen and the Singing Voice
Andrew Herxheimer
PLoS Med. 2005 September; 2(9): e310. Published online 2005 September 27. doi: 10.1371/journal.pmed.0020310.
PMCID: PMC1236804
Response to Stampfer Commentary
David F Williamson
PLoS Med. 2005 September; 2(9): e311. Published online 2005 September 27. doi: 10.1371/journal.pmed.0020311.
PMCID: PMC1236805
Author's Reply
Meir Stampfer
PLoS Med. 2005 September; 2(9): e326. Published online 2005 September 27. doi: 10.1371/journal.pmed.0020326.
PMCID: PMC1236811
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