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Volume 2(3);  March 2005
Editorial
How Does PLoS Medicine Manage Competing Interests?
The PLoS Medicine Editors
PLoS Med. 2005 March; 2(3): e88. Published online 2005 March 29. doi: 10.1371/journal.pmed.0020088.
PMCID: PMC1069676
Synopses
Early Detection of Disease Outbreaks
PLoS Med. 2005 March; 2(3): e65. Published online 2005 February 15. doi: 10.1371/journal.pmed.0020065.
PMCID: PMC548794
How Tumor Cells Acquire Resistance to Kinase Inhibitors
PLoS Med. 2005 March; 2(3): e74. Published online 2005 February 22. doi: 10.1371/journal.pmed.0020074.
PMCID: PMC549607
Uric Acid and the Heart
PLoS Med. 2005 March; 2(3): e90. Published online 2005 March 29. doi: 10.1371/journal.pmed.0020090.
PMCID: PMC1069677
Using Integrins for Tumor Imaging
PLoS Med. 2005 March; 2(3): e91. Published online 2005 March 29. doi: 10.1371/journal.pmed.0020091.
PMCID: PMC1069678
Cats and Allergies
PLoS Med. 2005 March; 2(3): e94. Published online 2005 March 29. doi: 10.1371/journal.pmed.0020094.
PMCID: PMC1069679
The PLoS Medicine Debate
Is It Always Unethical to Use a Placebo in a Clinical Trial?
Andreas Stang, Hans-Werner Hense, Karl-Heinz Jöckel, Erick H Turner, and Martin R Tramèr
PLoS Med. 2005 March; 2(3): e72. Published online 2005 March 29. doi: 10.1371/journal.pmed.0020072.
PMCID: PMC1069666
Essays
Alas, Poor Yorick: Digging Up the Dead to Make Medical Diagnoses
Deborah Hayden
PLoS Med. 2005 March; 2(3): e60. Published online 2005 March 29. doi: 10.1371/journal.pmed.0020060.
PMCID: PMC1069658
The Coming of Age of Multicultural Medicine
Gail McBride
PLoS Med. 2005 March; 2(3): e62. Published online 2005 March 29. doi: 10.1371/journal.pmed.0020062.
PMCID: PMC1069660
Neglected Diseases
Hookworm: “The Great Infection of Mankind”
Peter J Hotez, Jeff Bethony, Maria Elena Bottazzi, Simon Brooker, and Paulo Buss
PLoS Med. 2005 March; 2(3): e67. Published online 2005 March 29. doi: 10.1371/journal.pmed.0020067.
PMCID: PMC1069663
Perspectives
Designing an Equitable Strategy for Allocating Antiretroviral Treatments
Alexander M Capron and Andreas Reis
PLoS Med. 2005 March; 2(3): e69. Published online 2005 February 22. doi: 10.1371/journal.pmed.0020069.
PMCID: PMC549605
EGFR Inhibition in Non-Small Cell Lung Cancer: Resistance, Once Again, Rears Its Ugly Head
Jennifer Clark, Jan Cools, and D. Gary Gilliland
PLoS Med. 2005 March; 2(3): e75. Published online 2005 February 22. doi: 10.1371/journal.pmed.0020075.
PMCID: PMC549608
Health in Action
Creating Locally Relevant Health Information
Isabel Carter
PLoS Med. 2005 March; 2(3): e46. Published online 2005 March 29. doi: 10.1371/journal.pmed.0020046.
PMCID: PMC1069657
Antifibrinolytic Agents in Traumatic Haemorrhage
Tim Coats, Beverly Hunt, Ian Roberts, and Haleema Shakur
PLoS Med. 2005 March; 2(3): e64. Published online 2005 March 29. doi: 10.1371/journal.pmed.0020064.
PMCID: PMC1069662
Policy Forum
Protecting Children from Environmental Toxins
Bruce P Lanphear, Charles V Vorhees, and David C Bellinger
PLoS Med. 2005 March; 2(3): e61. Published online 2005 March 29. doi: 10.1371/journal.pmed.0020061.
PMCID: PMC1069659
Research in Translation
Exercise and Health: Can Biotechnology Confer Similar Benefits?
R. Sanders Williams and William E Kraus
PLoS Med. 2005 March; 2(3): e68. Published online 2005 March 29. doi: 10.1371/journal.pmed.0020068.
PMCID: PMC1069664
Case Report
Recurrent Pleural and Pericardial Effusions Due to Sarcoidosis
Sankar D Navaneethan, Sundar Venkatesh, Rakesh Shrivastava, Jagat Mehta, and Robert Israel
PLoS Med. 2005 March; 2(3): e63. Published online 2005 March 29. doi: 10.1371/journal.pmed.0020063.
PMCID: PMC1069661
Research Articles
A Space–Time Permutation Scan Statistic for Disease Outbreak Detection
Martin Kulldorff, Richard Heffernan, Jessica Hartman, Renato Assunção, and Farzad Mostashari
PLoS Med. 2005 March; 2(3): e59. Published online 2005 February 15. doi: 10.1371/journal.pmed.0020059.
PMCID: PMC548793
Noninvasive Visualization of the Activated αvβ3 Integrin in Cancer Patients by Positron Emission Tomography and [18F]Galacto-RGD
Roland Haubner, Wolfgang A Weber, Ambros J Beer, Eugenija Vabuliene, Daniel Reim, Mario Sarbia, Karl-Friedrich Becker, Michael Goebel, Rüdiger Hein, Hans-Jürgen Wester, Horst Kessler, and Markus Schwaiger
PLoS Med. 2005 March; 2(3): e70. Published online 2005 March 29. doi: 10.1371/journal.pmed.0020070.
PMCID: PMC1069665
Acquired Resistance of Lung Adenocarcinomas to Gefitinib or Erlotinib Is Associated with a Second Mutation in the EGFR Kinase Domain
William Pao, Vincent A Miller, Katerina A Politi, Gregory J Riely, Romel Somwar, Maureen F Zakowski, Mark G Kris, and Harold Varmus
PLoS Med. 2005 March; 2(3): e73. Published online 2005 February 22. doi: 10.1371/journal.pmed.0020073.
PMCID: PMC549606
Serum Uric Acid and Coronary Heart Disease in 9,458 Incident Cases and 155,084 Controls: Prospective Study and Meta-Analysis
Jeremy G Wheeler, Kelsey D. M Juzwishin, Gudny Eiriksdottir, Vilmundur Gudnason, and John Danesh
PLoS Med. 2005 March; 2(3): e76. Published online 2005 March 29. doi: 10.1371/journal.pmed.0020076.
PMCID: PMC1069667
T Cell Epitope Immunotherapy Induces a CD4+ T Cell Population with Regulatory Activity
Adrienne Verhoef, Clare Alexander, A. Barry Kay, and Mark Larché
PLoS Med. 2005 March; 2(3): e78. Published online 2005 March 29. doi: 10.1371/journal.pmed.0020078.
PMCID: PMC1069669
Correspondence and Other Communications
Tumor Cell Recognition Efficiency by T Cells
Daniel E Speiser, Jean-Charles Cerottini, and Pedro Romero
PLoS Med. 2005 March; 2(3): e77. Published online 2005 March 29. doi: 10.1371/journal.pmed.0020077.
PMCID: PMC1069668
Cholesterol, Statins, and Alzheimer Disease
Alexei R Koudinov and Temirbolat T Berezov
PLoS Med. 2005 March; 2(3): e81. Published online 2005 March 29. doi: 10.1371/journal.pmed.0020081.
PMCID: PMC1069670
Accounting for Individual Differences in Risk of Alzheimer Disease
William Grant
PLoS Med. 2005 March; 2(3): e82. Published online 2005 March 29. doi: 10.1371/journal.pmed.0020082.
PMCID: PMC1069671
A Canadian Perspective
James E Till
PLoS Med. 2005 March; 2(3): e83. Published online 2005 March 29. doi: 10.1371/journal.pmed.0020083.
PMCID: PMC1069672
Statement of Principles for Health Care Journalists
Gary Schwitzer
PLoS Med. 2005 March; 2(3): e84. Published online 2005 March 29. doi: 10.1371/journal.pmed.0020084.
PMCID: PMC1069673
Authors' Reply
Sam Gandy and Suzana Petanceska
PLoS Med. 2005 March; 2(3): e85. Published online 2005 March 29. doi: 10.1371/journal.pmed.0020085.
PMCID: PMC1069674
Author's Reply
Margaret Gatz
PLoS Med. 2005 March; 2(3): e86. Published online 2005 March 29. doi: 10.1371/journal.pmed.0020086.
PMCID: PMC1069675
Authors' Reply
Tor B Stuge and Peter P Lee
PLoS Med. 2005 March; 2(3): e95. Published online 2005 March 29. doi: 10.1371/journal.pmed.0020095.
PMCID: PMC1069680
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