[PTHE Membership Roster] [PTHE Meeting Rosters]

The Pathogenic Eukaryotes [PTHE] Study Section reviews applications involving protozoal, helminthic, fungal pathogens in humans and animal models. Specific areas covered by PTHE:

• Mechanisms of pathogenesis including: pathogen-host cell receptor interactions, signaling pathways in both host cell and pathogen, molecular mechanisms of virulence, manipulation of host cell biological pathways, and factors associated with asymptomatic infection and/or commensalisms
• Primary host defenses including: genetic basis of host resistance and susceptibility to infection and disease, induction and regulation of innate and acquired immunity, evasion of host immune response
• Biochemical processes of the pathogen including: metabolism, enzymology, physiology, and replication
• Identification and preclinical validation of potential chemotherapeutic targets and diagnostic strategies
• Pathogen cell biology including: novel organelles, secretory processes, and mechanisms of motility
• Pathogen differentiation, morphogenesis, and developmental processes required for the infectious cycle including transmission and persistence
• Genetic processes including: gene structure, regulation of gene expression, molecular evolution, genetic diversity, and improved genetic methodology
• Functional genomics, comparative genomics, proteomics, and other broad-based technologies for studying genomes
• Improved models of infectious cycles and diseases

Study sections with most closely related areas of similar science listed in rank order are:

Drug Discovery and Mechanisms of Antimicrobial Resistance [DDR]  
Innate Immunity And Inflammation [III]  
Immunity and Host Defense [IHD] 
Vector Biology [VB] 
AIDS-associated Opportunistic Infections and Cancer [AOIC]