Skip Navigation

HazMap: Occupational Exposure to Hazardous Agents
HazMap Home SIS Home NLM Home

as Search Agents Search Diseases Search Jobs Full Text Search


Haz-Map Home on-tab Custom Search on-tab Help on-tab Web Glossary on-tab Reference on-tab
left corner Browse Haz-Map
right corner
Agent Name Fluorotrichloromethane
Alternative Name Trichlorofluoromethane
CAS Number 75-69-4
Formula C-Cl3-F
Major Category Solvents
Synonyms Algofrene type 1; Arcton 11; Arcton 9; CFC 11; Chladone 11; Daiflon 11; Daiflon S 1; Dymel 11; Electro-CF 11; Eskimon 11; F 11; F 11 (halocarbon); F 11B; F-11; FC 11; FC 11 (halocarbon); FKW 11; Fluon 11; Fluorocarbon 11; Fluorocarbon No. 11; Fluorochloroform; Fluorotrichloromethane; Fluorotrojchlorometan [Polish]; Freon 11; Freon 11A; Freon 11B; Freon HE; Freon MF; Frigen 11; Frigen 11A; Frigen S 11; Genetron 11; Genetron 11SBA; Halocarbon 11; Halon 11; Isceon 131; Isotron 11; Kaltron 11; Khladon 11; Ledon 11; Methane, fluorotrichloro-; Monofluorotrichloromethane; Propellant 11; R 11; R 11 (refrigerant); Refrigerant 11; Refrigerant R 11; Trichlorofluorocarbon; Trichlorofluoromethane; Trichloromethyl fluoride; Trichloromonofluoromethane; Ucon flurocarbon 11; Ucon refrigerant 11; [ChemIDplus] UN2810
Category Chlorofluorocarbons
Description Colorless to water-white, nearly odorless liquid or gas (above 75 degrees F); [NIOSH]
Sources/Uses CFC-11 has been used as a blowing agent, a refrigerant, and an aerosol propellant. [ACGIH] Used in photography (film cleaner); [www.ci.tucson.az.us/arthazards/medium.html]
Comments Fluorotrichloromethane is in the list of "Some volatile substances which may be abused by inhalation" published on the web site of the U.N. International Drug Control Programme, indicating its potential to cause narcosis in workers. [Reference #1] Evaporating liquid can cause frostbite; Inhalation of high concentrations can cause CNS depression and cardiac arrhythmias; [ICSC]
Restricted See CHLOROFLUOROCARBONS
Reference Link Volatile Substance Abuse
Exposure Assessment
Skin Designation (ACGIH) No
Ceiling (ACGIH) 1000 ppm
PEL (OSHA) 1000 ppm
MAK 1000 ppm
IDLH (NIOSH) 2000 ppm
Excerpts from Documentation for IDLHs Evidence of serious arrhythmia was noted in 1 of 12 conscious dogs exposed for 5 minutes to 5,000 ppm plus intravenous epinephrine [Reinhardt et al. 1971]. However, in another study, endogenous epinephrin was not sufficient to precipitate arrythmia in dogs exposed to 5,000 to 10,000 ppm [Reinhardt et al. 1971].
Vapor Pressure 803 mm Hg
Odor Threshold Low 200000 ppm
Lethal Concentration LC50 (rats) = 130,000 ppm/15 min
Explanatory Notes Odor threshold is 200,000 ppm (20% by volume). [CHEMINFO]
Adverse Effects
Neurotoxin CNS Solvent Syndrome
Links to Other NLM Databases
Health Studies Human Health Effects from Hazardous Substances Data Bank: TRICHLOROFLUOROMETHANE  
Toxicity Information Search TOXNET
Chemical Information Search ChemIDplus
Biomedical References Search PubMed
Related Information in Haz-Map
Diseases Occupational diseases associated with exposure to this agent:
Processes Industrial Processes with risk of exposure:





Specialized Information Services   U.S. National Library of Medicine,
8600 Rockville Pike, Bethesda, MD 20894
National Institutes of Health
Privacy/Disclaimer Notice
Customer Service: tehip@teh.nlm.nih.gov
Last updated: January, 2009