| Agent Name |
Dichlorodifluoromethane |
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| Alternative Name |
Refrigerant 12 |
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| CAS Number |
75-71-8 |
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| Formula |
C-Cl2-F2 |
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| Major Category |
Solvents |
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| Synonyms |
Algofrene type 2; Arcton 12; Arcton 6; CFC 12; Chlorofluorocarbon 12; Dichlorodifluoromethane; Diclorodifluometano [Spanish]; Difluorodichloromethane; Dwuchlorodwufluorometan [Polish]; Dymel 12; Electro-CF 12; Eskimon 12; F 12; F 12; FC 12; FCC 12; FKW 12; Fluorocarbon-12; Forane 12; Freon 12; Freon F-12; Frigen 12; Genetron 12; Halon; Halon 122; Isceon 122; Isotron 12; Isotron 2; Kaiser chemicals 12; Ledon 12; Methane, dichlorodifluoro-; Propellant 12; R 12 (refrigerant); Refrigerant 12; Refrigerant R 12; Ucon 12; Ucon 12/halocarbon 12; [ChemIDplus] UN1028; UN1078 |
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| Category |
Chlorofluorocarbons |
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| Description |
Colorless gas with an ether-like odor at extremely high concentrations; Note: Shipped as a liquefied compressed gas; [NIOSH] |
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| Sources/Uses |
Has been used as a refrigerant, propellant, and blowing agent; [ACGIH] Used in photography (film cleaner); [www.ci.tucson.az.us/arthazards/medium.html] |
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| Comments |
Possible frostbite from contact with liquid; [NIOSH] Dichlorodifluoromethane is in the list of "Some volatile substances which may be abused by inhalation" published on the web site of the U.N. International Drug Control Programme, indicating its potential to cause narcosis in workers. [Reference #1] Release in confined space may result in suffocation; May cause CNS depression and cardiac arryhthmias; [ICSC] |
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| Restricted |
The manufacture of products containing CFC-12 propellants was banned by the EPA in 1978. [ACGIH] |
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| Reference Link |
Volatile Substance Abuse |
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| Exposure Assessment |
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| Skin Designation (ACGIH) |
No |
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| TLV (ACGIH) |
1000 ppm |
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| PEL (OSHA) |
1000 ppm |
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| MAK |
1000 ppm |
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| IDLH (NIOSH) |
15000 ppm |
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| Excerpts from Documentation for IDLHs |
Exposure up to 60,000 ppm was tolerated for 80 minutes by 1 volunteer [NRC 1984]; when exposed at 40,000 ppm for 14 minutes and then at 20,000 ppm for 66 minutes, another volunteer developed EEG changes and had slurred speech and decreased psychologic test scores [NRC 1984]. |
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| Lethal Concentration |
LC50 (guinea pigs) = 800,000ppm/30 min |
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| Adverse Effects |
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| Neurotoxin |
CNS Solvent Syndrome |
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| Other Poison |
Simple Asphyxiant |
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| Links to Other NLM Databases |
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| Health Studies |
Human Health Effects from Hazardous Substances Data Bank: DICHLORODIFLUOROMETHANE
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