Aida Cremesti, Ph.D.

Dr. Cremesti received her Ph.D. in Biological Sciences from the University of Rhode Island in 2000. She did her dissertation research on sphingolipid metabolism in yeast, where she developed novel enzymatic purification protocols, enzyme activity assays, and HPLC methods for quantifying sphingolipids. Following graduate school, Dr. Cremesti did postdoctoral work in Memorial Sloan-Kettering Cancer Center, Columbia University and NCI where she conducted research in apoptosis particularly the Fas death receptor, and the role of membrane rafts and sphingolipids in mediating Fas signaling and activation. She also worked on elucidating the role of several novel genes, including a guanine nucleotide exchange factor, and an MMTV integration site gene in signaling and cellular transformation, invasion and metastasis, apoptosis and cellular trafficking. She identified cellular signaling partners using different proteomic approaches and yeast-2-hybrid techniques, and studied protein-protein interactions between various signaling proteins. Prior to joining NCI TTB, Dr. Cremesti worked at the NIH Office of Technology Transfer where she was involved in drafting and negotiating license agreements, evaluating novel technologies for patentability, licensing and commercial potential, and analyzing market areas and developing marketing materials.

cremesta@mail.nih.gov

Associated Labs

• Center for Cancer Research : Laboratory of Cellular Oncology
• Center for Cancer Research : Cell and Cancer Biology Branch
• Center for Cancer Research : Experimental Transplantation and Immunology Branch
• Center for Cancer Research : Basic Research Laboratory
• Center for Cancer Research : Mammary Biology and Tumorigenesis Laboratory
• Center for Cancer Research : Dermatology Branch