A Longitudinal Study of Plasma EBV DNA in Nasopharyngeal Carcinoma From Both Endemic and Non-Endemic Patient Populations

This study is currently recruiting participants.

Verified by Stanford University, September 2008

Sponsors and Collaborators:	Stanford University National Institutes of Health (NIH)
Information provided by:	Stanford University
ClinicalTrials.gov Identifier:	NCT00186433

Purpose

To determine the prognostic implication of plasma Epstein-Bar Virus (EBV) DNA concentrations, as measured by quantitative polymerase chain reaction (PCR) in patients with nasopharyngeal carcinoma (NPC).
To relate pretreatment plasma EBV DNA concentration to WHO classification of these tumors both in endemic and non-endemic areas.
To determine whether pretreatment plasma EBV DNA can serve as a prognostic factor for both endemic and non-endemic patient populations.

Condition
Lip Neoplasms Throat Cancer Lip Cancer Mouth Cancer

MedlinePlus related topics: Cancer Oral Cancer

Study Type:	Observational
Study Design:	Prospective
Official Title:	A Longitudinal Study of Plasma EBV DNA in Nasopharyngeal Carcinoma From Both Endemic and Non-Endemic Patient Populations

Further study details as provided by Stanford University:

Estimated Enrollment:	150
Study Start Date:	November 2001

Eligibility

Criteria

Inclusion Criteria:- Having a new diagnosis of Nasopharyngeal carcinoma.

Being treated with either radiotherapy or chemoradiotherapy for this condition.
 Exclusion Criteria:- Age <18 since NPC is a very rare condition in this age group and may have a different biological behavior
Patients who are unable to provide informed consents for themselves.

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00186433

Locations

United States, California
Stanford University School of Medicine	Recruiting
Stanford, California, United States, 94305
Contact: Quynh-Thu Le 650-498-6184 qle@stanford.edu
Contact: Cancer Clinical Trials Office (650) 498-7061
Principal Investigator: Quynh-Thu Le
Sub-Investigator: Harlan Pinto
Sub-Investigator: James L Zehnder
Sub-Investigator: Dr. Billy W. Loo Jr. M.D. Ph.D.

Sponsors and Collaborators

Stanford University

National Institutes of Health (NIH)

Investigators

Principal Investigator:

Quynh-Thu Le

Stanford University

More Information

Study ID Numbers:	ENT0006, ENT0006, NCT00186433
Study First Received:	September 13, 2005
Last Updated:	October 3, 2008
ClinicalTrials.gov Identifier:	NCT00186433
Health Authority:	United States: Institutional Review Board

Study placed in the following topic categories:

Mouth Diseases
Otorhinolaryngologic Neoplasms
Otorhinolaryngologic Diseases
Pharyngeal Neoplasms
Mouth Neoplasms
Lip Neoplasms
Pharyngeal Diseases

Nasopharyngeal Neoplasms
Carcinoma
Nasopharyngeal carcinoma
Head and Neck Neoplasms
Oral cancer
Stomatognathic Diseases

Additional relevant MeSH terms:

Neoplasms
Neoplasms by Site
Nasopharyngeal Diseases
Lip Diseases

ClinicalTrials.gov processed this record on January 15, 2009