| | This journal provides immediate access to some articles. Opinion The Sicker Sex Marlene Zuk PLoS Pathog. 2009 January; 5(1): e1000267. Published online 2009 January 30. doi: 10.1371/journal.ppat.1000267.PMCID: PMC2628977 Research Articles Transmission of Influenza Virus in a Mammalian Host Is Increased by PB2 Amino Acids 627K or 627E/701N John Steel, Anice C. Lowen, Samira Mubareka, and Peter Palese PLoS Pathog. 2009 January; 5(1): e1000252. Published online 2009 January 2. doi: 10.1371/journal.ppat.1000252.PMCID: PMC2603332 Quantitative Models of In Vitro Bacteriophage–Host Dynamics and Their Application to Phage Therapy Benjamin J. Cairns, Andrew R. Timms, Vincent A. A. Jansen, Ian F. Connerton, and Robert J. H. Payne PLoS Pathog. 2009 January; 5(1): e1000253. Published online 2009 January 2. doi: 10.1371/journal.ppat.1000253.PMCID: PMC2603284 Positive Selection Results in Frequent Reversible Amino Acid Replacements in the G Protein Gene of Human Respiratory Syncytial Virus Viviane F. Botosso, Paolo M. de A. Zanotto, Mirthes Ueda, Eurico Arruda, Alfredo E. Gilio, Sandra E. Vieira, Klaus E. Stewien, Teresa C. T. Peret, Leda F. Jamal, Maria I. de M. C. Pardini, João R. R. Pinho, Eduardo Massad, Osvaldo A. Sant'Anna, Eddie C. Holmes, Edison L. Durigon, and and the VGDN Consortium PLoS Pathog. 2009 January; 5(1): e1000254. Published online 2009 January 2. doi: 10.1371/journal.ppat.1000254.PMCID: PMC2603285 The Epstein-Barr Virus G-Protein-Coupled Receptor Contributes to Immune Evasion by Targeting MHC Class I Molecules for Degradation Jianmin Zuo, Andrew Currin, Bryan D. Griffin, Claire Shannon-Lowe, Wendy A. Thomas, Maaike E. Ressing, Emmanuel J. H. J. Wiertz, and Martin Rowe PLoS Pathog. 2009 January; 5(1): e1000255. Published online 2009 January 2. doi: 10.1371/journal.ppat.1000255.PMCID: PMC2603334 An Upstream Open Reading Frame Controls Translation of var2csa, a Gene Implicated in Placental Malaria Borko Amulic, Ali Salanti, Thomas Lavstsen, Morten A. Nielsen, and Kirk W. Deitsch PLoS Pathog. 2009 January; 5(1): e1000256. Published online 2009 January 2. doi: 10.1371/journal.ppat.1000256.PMCID: PMC2603286 Role of Intraspecies Recombination in the Spread of Pathogenicity Islands within the Escherichia coli Species Sören Schubert, Pierre Darlu, Olivier Clermont, Andreas Wieser, Giuseppe Magistro, Christiane Hoffmann, Kirsten Weinert, Olivier Tenaillon, Ivan Matic, and Erick Denamur PLoS Pathog. 2009 January; 5(1): e1000257. Published online 2009 January 9. doi: 10.1371/journal.ppat.1000257.PMCID: PMC2606025 A Role for the Unfolded Protein Response (UPR) in Virulence and Antifungal Susceptibility in Aspergillus fumigatus Daryl L. Richie, Lukas Hartl, Vishukumar Aimanianda, Michael S. Winters, Kevin K. Fuller, Michael D. Miley, Stephanie White, Jason W. McCarthy, Jean-Paul Latgé, Marta Feldmesser, Judith C. Rhodes, and David S. Askew PLoS Pathog. 2009 January; 5(1): e1000258. Published online 2009 January 9. doi: 10.1371/journal.ppat.1000258.PMCID: PMC2606855 A Novel Co-Crystal Structure Affords the Design of Gain-of-Function Lentiviral Integrase Mutants in the Presence of Modified PSIP1/LEDGF/p75 Stephen Hare, Ming-Chieh Shun, Saumya Shree Gupta, Eugene Valkov, Alan Engelman, and Peter Cherepanov PLoS Pathog. 2009 January; 5(1): e1000259. Published online 2009 January 9. doi: 10.1371/journal.ppat.1000259.PMCID: PMC2606027 Control of Stochastic Gene Expression by Host Factors at the HIV Promoter John C. Burnett, Kathryn Miller-Jensen, Priya S. Shah, Adam P. Arkin, and David V. Schaffer PLoS Pathog. 2009 January; 5(1): e1000260. Published online 2009 January 9. doi: 10.1371/journal.ppat.1000260.PMCID: PMC2607019 Genomic Survey of the Non-Cultivatable Opportunistic Human Pathogen, Enterocytozoon bieneusi Donna E. Akiyoshi, Hilary G. Morrison, Shi Lei, Xiaochuan Feng, Quanshun Zhang, Nicolas Corradi, Harriet Mayanja, James K. Tumwine, Patrick J. Keeling, Louis M. Weiss, and Saul Tzipori PLoS Pathog. 2009 January; 5(1): e1000261. Published online 2009 January 9. doi: 10.1371/journal.ppat.1000261.PMCID: PMC2607024 Distinct Roles of Plasmodium Rhomboid 1 in Parasite Development and Malaria Pathogenesis Prakash Srinivasan, Isabelle Coppens, and Marcelo Jacobs-Lorena PLoS Pathog. 2009 January; 5(1): e1000262. Published online 2009 January 16. doi: 10.1371/journal.ppat.1000262.PMCID: PMC2607553 miR-198 Inhibits HIV-1 Gene Expression and Replication in Monocytes and Its Mechanism of Action Appears To Involve Repression of Cyclin T1 Tzu-Ling Sung and Andrew P. Rice PLoS Pathog. 2009 January; 5(1): e1000263. Published online 2009 January 16. doi: 10.1371/journal.ppat.1000263.PMCID: PMC2607557 Imbalanced Lignin Biosynthesis Promotes the Sexual Reproduction of Homothallic Oomycete Pathogens Michaël Quentin, Valérie Allasia, Anthony Pegard, Florent Allais, Paul-Henri Ducrot, Bruno Favery, Caroline Levis, Sophie Martinet, Clarissa Masur, Michel Ponchet, Dominique Roby, Nikolaus L. Schlaich, Lise Jouanin, and Harald Keller PLoS Pathog. 2009 January; 5(1): e1000264. Published online 2009 January 16. doi: 10.1371/journal.ppat.1000264.PMCID: PMC2613516 Malaria Parasite Invasion of the Mosquito Salivary Gland Requires Interaction between the Plasmodium TRAP and the Anopheles Saglin Proteins Anil K. Ghosh, Martin Devenport, Deepa Jethwaney, Dario E. Kalume, Akhilesh Pandey, Vernon E. Anderson, Ali A. Sultan, Nirbhay Kumar, and Marcelo Jacobs-Lorena PLoS Pathog. 2009 January; 5(1): e1000265. Published online 2009 January 16. doi: 10.1371/journal.ppat.1000265.PMCID: PMC2613030 Parasitic Nematodes Modulate PIN-Mediated Auxin Transport to Facilitate Infection Wim Grunewald, Bernard Cannoot, Jiří Friml, and Godelieve Gheysen PLoS Pathog. 2009 January; 5(1): e1000266. Published online 2009 January 16. doi: 10.1371/journal.ppat.1000266.PMCID: PMC2613529 Gain of Function Mutations in CgPDR1 of Candida glabrata Not Only Mediate Antifungal Resistance but Also Enhance Virulence Sélène Ferrari, Françoise Ischer, David Calabrese, Brunella Posteraro, Maurizio Sanguinetti, Giovanni Fadda, Bettina Rohde, Christopher Bauser, Oliver Bader, and Dominique Sanglard PLoS Pathog. 2009 January; 5(1): e1000268. Published online 2009 January 16. doi: 10.1371/journal.ppat.1000268.PMCID: PMC2607542 Genomic Analysis Reveals a Potential Role for Cell Cycle Perturbation in HCV-Mediated Apoptosis of Cultured Hepatocytes Kathie-Anne Walters, Andrew J. Syder, Sharon L. Lederer, Deborah L. Diamond, Bryan Paeper, Charles M. Rice, and Michael G. Katze PLoS Pathog. 2009 January; 5(1): e1000269. Published online 2009 January 16. doi: 10.1371/journal.ppat.1000269.PMCID: PMC2613535 Rab11A-Controlled Assembly of the Inner Membrane Complex Is Required for Completion of Apicomplexan Cytokinesis Carolina Agop-Nersesian, Bernina Naissant, Fathia Ben Rached, Manuel Rauch, Angelika Kretzschmar, Sabine Thiberge, Robert Menard, David J. P. Ferguson, Markus Meissner, and Gordon Langsley PLoS Pathog. 2009 January; 5(1): e1000270. Published online 2009 January 23. doi: 10.1371/journal.ppat.1000270.PMCID: PMC2622761 The IpaC Carboxyterminal Effector Domain Mediates Src-Dependent Actin Polymerization during Shigella Invasion of Epithelial Cells Joëlle Mounier, Michel R. Popoff, Jost Enninga, Margaret C. Frame, Philippe J. Sansonetti, and Guy Tran Van Nhieu PLoS Pathog. 2009 January; 5(1): e1000271. Published online 2009 January 23. doi: 10.1371/journal.ppat.1000271.PMCID: PMC2621354 Immunization with Single-Cycle SIV Significantly Reduces Viral Loads After an Intravenous Challenge with SIVmac239 Bin Jia, Sharon K. Ng, M. Quinn DeGottardi, Michael Piatak, Jr., Eloísa Yuste, Angela Carville, Keith G. Mansfield, Wenjun Li, Barbra A. Richardson, Jeffrey D. Lifson, and David T. Evans PLoS Pathog. 2009 January; 5(1): e1000272. Published online 2009 January 23. doi: 10.1371/journal.ppat.1000272.PMCID: PMC2621341 An Inhibitory Antibody Blocks Interactions between Components of the Malarial Invasion Machinery Christine R. Collins, Chrislaine Withers-Martinez, Fiona Hackett, and Michael J. Blackman PLoS Pathog. 2009 January; 5(1): e1000273. Published online 2009 January 23. doi: 10.1371/journal.ppat.1000273.PMCID: PMC2621342 Inflammatory Genital Infections Mitigate a Severe Genetic Bottleneck in Heterosexual Transmission of Subtype A and C HIV-1 Richard E. Haaland, Paulina A. Hawkins, Jesus Salazar-Gonzalez, Amber Johnson, Amanda Tichacek, Etienne Karita, Olivier Manigart, Joseph Mulenga, Brandon F. Keele, George M. Shaw, Beatrice H. Hahn, Susan A. Allen, Cynthia A. Derdeyn, and Eric Hunter PLoS Pathog. 2009 January; 5(1): e1000274. Published online 2009 January 23. doi: 10.1371/journal.ppat.1000274.PMCID: PMC2621345 Viral Mimicry of Cdc2/Cyclin-Dependent Kinase 1 Mediates Disruption of Nuclear Lamina during Human Cytomegalovirus Nuclear Egress Sofia Hamirally, Jeremy P. Kamil, Yasmine M. Ndassa-Colday, Alison J. Lin, Wan Jin Jahng, Moon-Chang Baek, Sarah Noton, Laurie A. Silva, Martha Simpson-Holley, David M. Knipe, David E. Golan, Jarrod A. Marto, and Donald M. Coen PLoS Pathog. 2009 January; 5(1): e1000275. Published online 2009 January 23. doi: 10.1371/journal.ppat.1000275.PMCID: PMC2625439 Trypanosome Lytic Factor, an Antimicrobial High-Density Lipoprotein, Ameliorates Leishmania Infection Marie Samanovic, Maria Pilar Molina-Portela, Anne-Danielle C. Chessler, Barbara A. Burleigh, and Jayne Raper PLoS Pathog. 2009 January; 5(1): e1000276. Published online 2009 January 23. doi: 10.1371/journal.ppat.1000276.PMCID: PMC2622765 The Cell Adhesion Molecule “CAR” and Sialic Acid on Human Erythrocytes Influence Adenovirus In Vivo Biodistribution Elena Seiradake, Daniel Henaff, Harald Wodrich, Olivier Billet, Matthieu Perreau, Claire Hippert, Franck Mennechet, Guy Schoehn, Hugues Lortat-Jacob, Hanna Dreja, Sandy Ibanes, Vasiliki Kalatzis, Jennifer P. Wang, Robert W. Finberg, Stephen Cusack, and Eric J. Kremer PLoS Pathog. 2009 January; 5(1): e1000277. Published online 2009 January 2. doi: 10.1371/journal.ppat.1000277.PMCID: PMC2607015 A Legionella pneumophila Effector Protein Encoded in a Region of Genomic Plasticity Binds to Dot/Icm-Modified Vacuoles Shira Ninio, Jean Celli, and Craig R. Roy PLoS Pathog. 2009 January; 5(1): e1000278. Published online 2009 January 23. doi: 10.1371/journal.ppat.1000278.PMCID: PMC2621349 Selective Transmission of R5 HIV-1 over X4 HIV-1 at the Dendritic Cell–T Cell Infectious Synapse Is Determined by the T Cell Activation State Takuya Yamamoto, Yasuko Tsunetsugu-Yokota, Yu-ya Mitsuki, Fuminori Mizukoshi, Takatsugu Tsuchiya, Kazutaka Terahara, Yoshio Inagaki, Naoki Yamamoto, Kazuo Kobayashi, and Jun-ichiro Inoue PLoS Pathog. 2009 January; 5(1): e1000279. Published online 2009 January 30. doi: 10.1371/journal.ppat.1000279.PMCID: PMC2627922 Rotavirus NSP1 Inhibits NFκB Activation by Inducing Proteasome-Dependent Degradation of β-TrCP: A Novel Mechanism of IFN Antagonism Joel W. Graff, Khalil Ettayebi, and Michele E. Hardy PLoS Pathog. 2009 January; 5(1): e1000280. Published online 2009 January 30. doi: 10.1371/journal.ppat.1000280.PMCID: PMC2627925 Estimation of Transmission Parameters of H5N1 Avian Influenza Virus in Chickens Annemarie Bouma, Ivo Claassen, Ketut Natih, Don Klinkenberg, Christl A. Donnelly, Guus Koch, and Michiel van Boven PLoS Pathog. 2009 January; 5(1): e1000281. Published online 2009 January 30. doi: 10.1371/journal.ppat.1000281.PMCID: PMC2627927 Local Inflammation Induces Complement Crosstalk Which Amplifies the Antimicrobial Response Jing Zhang, Jingyun Koh, Jinhua Lu, Steffen Thiel, Benjamin S. H. Leong, Sunil Sethi, Cynthia Y. X. He, Bow Ho, and Jeak L. Ding PLoS Pathog. 2009 January; 5(1): e1000282. Published online 2009 January 30. doi: 10.1371/journal.ppat.1000282.PMCID: PMC2629585 Diploids in the Cryptococcus neoformans Serotype A Population Homozygous for the α Mating Type Originate via Unisexual Mating Xiaorong Lin, Sweta Patel, Anastasia P. Litvintseva, Anna Floyd, Thomas G. Mitchell, and Joseph Heitman PLoS Pathog. 2009 January; 5(1): e1000283. Published online 2009 January 30. doi: 10.1371/journal.ppat.1000283.PMCID: PMC2629120 Glutathione Provides a Source of Cysteine Essential for Intracellular Multiplication of Francisella tularensis Khaled Alkhuder, Karin L. Meibom, Iharilalao Dubail, Marion Dupuis, and Alain Charbit PLoS Pathog. 2009 January; 5(1): e1000284. Published online 2009 January 30. doi: 10.1371/journal.ppat.1000284.PMCID: PMC2629122 Polar Localization of Virulence-Related Esx-1 Secretion in Mycobacteria Fredric Carlsson, Shilpa A. Joshi, Linda Rangell, and Eric J. Brown PLoS Pathog. 2009 January; 5(1): e1000285. Published online 2009 January 30. doi: 10.1371/journal.ppat.1000285.PMCID: PMC2628743 |