Note: These protocols are not currently available on-line. If you would like copies of any or all of
these master protocols, please contact the T&PB. In the near future, downloadable Acrobat pdf files will be
available.
Mice
|
Protocol Title
|
Protocol Number
|
|
Dose Range-Finding Study In Male Mice
|
1-updown.bio
|
|
Single Dose Lethality In Study Mice
|
1-x1-ms.let
|
|
Single Dose Range-Finding Study In Male Mice
|
1-ac-ms.tox
|
|
Single Dose Toxicity Study In Mice
|
1-x1-ms.tox
|
|
Five Daily Dose Lethality Study In Mice
|
1-x5-ms.let
|
|
Five Daily Dose Toxicity Study In Mice
|
1-x5-ms.tox
|
Rats
|
Protocol Title
|
Protocol Number
|
|
Pharmacokinetic Study In Rats
|
1-rat.pk
|
|
Single Dose Toxicity Study In Rats
|
1-x1-rat.tox
|
|
Five-Day Multiple Dose Range-Finding Study In Rats
|
1-ac-rat.tox
|
|
Five Daily Dose Toxicity Study In Rats
|
1-x5-rat.tox
|
|
120-Hour Continuous Intravenous Infusion Study In Rats
|
1-civrat.tox
|
|
14-Day Toxicity Study In Rats
|
1-14-rat.tox
|
|
28-Day Toxicity Study In Rats
|
1-28-rat.tox
|
Dogs
|
Protocol Title
|
Protocol Number
|
|
Pharmacokinetics and Dose Range-Finding Study In Beagle Dogs
|
1-rf-dog.pk
|
|
Bioavailability Study In Beagle Dogs
|
1-biodog.pk
|
|
Single Dose Toxicity Study In Beagle Dogs
|
1-x1-dog.tox
|
|
Five Daily Dose Toxicity Study In Beagle Dogs
|
1-x5-dog.tox
|
|
120-Hour Continuous Intravenous Infusion Toxicity Study In Beagle Dogs
|
1-civdog.tox
|
|
14-Day Toxicity Study In Beagle Dogs
|
1-14-dog.tox
|
|
28-Day Toxicity Study In Beagle Dogs
|
1-28-dog.tox
|
Special Studies
|
Protocol Title
|
Protocol Number
|
|
Vaccine Safety/Immunotoxicity Study In Mice
|
Vac-Imm-M.saf
|
|
Multiple Dose Toxicity by the Intraventricular Route in Rats
|
Qod-it-r.tox
|
|
Neurological Functional Observation Battery (Rats or Mice)
|
NeuroFOB
|
|
Single Dose Cardiotoxicity in Cynomolgus Monkeys
|
Mky-Card.tox
|
|
Single Dose Neurotoxicity In Beagle Dogs
|
DogNeuro.tox
|
|
Vaccine Immunization Safety Study in Monkeys
|
1-Vac-Mky
|
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