| | This journal provides immediate access to some articles. Commentaries The ins and outs of presenilin 1 membrane topology Jinoh Kim and Randy Schekman PMCID: PMC327113 Quantal size fits central synaptic depression Richard W. Ordway PMCID: PMC327114 Physical Sciences Computer Sciences Evidence for complex, collective dynamics and emergent, distributed computation in plants David Peak, Jevin D. West, Susanna M. Messinger, and Keith A. Mott PMCID: PMC327117 Biological Sciences Biochemistry The tethered configuration of the EGF receptor extracellular domain exerts only a limited control of receptor function Dawn Mattoon, Peter Klein, Mark A. Lemmon, Irit Lax, and Joseph Schlessinger PMCID: PMC327118 A structure-based model for ligand binding and dimerization of EGF receptors Peter Klein, Dawn Mattoon, Mark A. Lemmon, and Joseph Schlessinger PMCID: PMC327119 Insights into the molecular basis for fibroblast growth factor receptor autoinhibition and ligand-binding promiscuity Shaun K. Olsen, Omar A. Ibrahimi, Angela Raucci, Fuming Zhang, Anna V. Eliseenkova, Avner Yayon, Claudio Basilico, Robert J. Linhardt, Joseph Schlessinger, and Moosa Mohammadi PMCID: PMC327120 Vertebrate ultraviolet visual pigments: Protonation of the retinylidene Schiff base and a counterion switch during photoactivation Ana Karin Kusnetzow, Abhiram Dukkipati, Kunnel R. Babu, Lavoisier Ramos, Barry E. Knox, and Robert R. Birge PMCID: PMC327121 Simian virus 40 large T antigen targets the spindle assembly checkpoint protein Bub1 Marina Cotsiki, Rowena L. Lock, Yuan Cheng, Grace L. Williams, Jean Zhao, David Perera, Raimundo Freire, Alan Entwistle, Erica A. Golemis, Thomas M. Roberts, Parmjit S. Jat, and Ole V. Gjoerup PMCID: PMC327122 From the Cover:
A serine protease zymogen functions as a pattern-recognition receptor for lipopolysaccharides Shigeru Ariki, Kumiko Koori, Tsukasa Osaki, Kiyohito Motoyama, Kei-ichiro Inamori, and Shun-ichiro Kawabata PMCID: PMC327123 Biophysics The evolution of transmembrane helix kinks and the structural diversity of G protein-coupled receptors Sarah Yohannan, Salem Faham, Duan Yang, Julian P. Whitelegge, and James U. Bowie PMCID: PMC327124 Cell Biology Functional dissection of the interactions of stonin 2 with the adaptor complex AP-2 and synaptotagmin Kristin Walther, M. Kasim Diril, Nadja Jung, and Volker Haucke PMCID: PMC327125 From the Cover:
Visualization of spatially and temporally regulated N-WASP activity during cytoskeletal reorganization in living cells Michael E. Ward, Jane Y. Wu, and Yi Rao PMCID: PMC327126 Evolution Mutations arising in the wave front of an expanding population Christopher A. Edmonds, Anita S. Lillie, and L. Luca Cavalli-Sforza PMCID: PMC327127 Genetics Coregulator-dependent facilitation of chromatin occupancy by GATA-1 Saumen Pal, Alan B. Cantor, Kirby D. Johnson, Tyler B. Moran, Meghan E. Boyer, Stuart H. Orkin, and Emery H. Bresnick PMCID: PMC327128 A functional cellulose synthase from ascidian epidermis Ann G. Matthysse, Karine Deschet, Melanie Williams, Mazz Marry, Alan R. White, and William C. Smith PMCID: PMC327129 From the Cover:
Identifying gene regulatory elements by genome-wide recovery of DNase hypersensitive sites Gregory E. Crawford, Ingeborg E. Holt, James C. Mullikin, Denise Tai, National Institutes of Health Intramural Sequencing Center, Eric D. Green, Tyra G. Wolfsberg, and Francis S. Collins PMCID: PMC327130 Immunology T cell repertoire scanning is promoted by dynamic dendritic cell behavior and random T cell motility in the lymph node Mark J. Miller, Arsalan S. Hejazi, Sindy H. Wei, Michael D. Cahalan, and Ian Parker PMCID: PMC327133 Complex and dynamic redistribution of NF-κB signaling intermediates in response to T cell receptor stimulation Brian C. Schaefer, John W. Kappler, Abraham Kupfer, and Philippa Marrack PMCID: PMC327141 Germinal center-associated nuclear protein contributes to affinity maturation of B cell antigen receptor in T cell-dependent responses Kazuhiko Kuwahara, Satoru Fujimura, Yoshimasa Takahashi, Naomi Nakagata, Toshitada Takemori, Shinichi Aizawa, and Nobuo Sakaguchi PMCID: PMC327142 Ly49Q, a member of the Ly49 family that is selectively expressed on myeloid lineage cells and involved in regulation of cytoskeletal architecture Noriko Toyama-Sorimachi, Yusuke Tsujimura, Mikako Maruya, Atsuko Onoda, Toshiyuki Kubota, Shigeo Koyasu, Kayo Inaba, and Hajime Karasuyama PMCID: PMC327143 Lipid–protein interactions: Biosynthetic assembly of CD1 with lipids in the endoplasmic reticulum is evolutionarily conserved Jang-June Park, Suk-Jo Kang, A. Dharshan De Silva, Aleksandar K. Stanic, Giulia Casorati, David L. Hachey, Peter Cresswell, and Sebastian Joyce PMCID: PMC327144 Selection of B lymphocytes in the periphery is determined by the functional capacity of the B cell antigen receptor Leo D. Wang, Jared Lopes, A. Byron Cooper, May Dang-Lawson, Linda Matsuuchi, and Marcus R. Clark PMCID: PMC327145 Medical Sciences Direct interactions between Epstein–Barr virus leader protein LP and the EBNA2 acidic domain underlie coordinate transcriptional regulation Chih-Wen Peng, Yong Xue, Bo Zhao, Eric Johannsen, Elliott Kieff, and Shizuko Harada PMCID: PMC327146 Automated array-based genomic profiling in chronic lymphocytic leukemia: Development of a clinical tool and discovery of recurrent genomic alterations Carsten Schwaenen, Michelle Nessling, Swen Wessendorf, Tatjana Salvi, Gunnar Wrobel, Bernhard Radlwimmer, Hans A. Kestler, Christian Haslinger, Stephan Stilgenbauer, Hartmut Döhner, Martin Bentz, and Peter Lichter PMCID: PMC327147 Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41 Yumei Xiong, Norimasa Miyamoto, Kenji Shibata, Mark A. Valasek, Toshiyuki Motoike, Rafal M. Kedzierski, and Masashi Yanagisawa PMCID: PMC327148 Neuroscience Calcium influx through hyperpolarization-activated cation channels (Ih channels) contributes to activity-evoked neuronal secretion Xiao Yu, Kai-Lai Duan, Chun-Feng Shang, Han-Gang Yu, and Zhuan Zhou PMCID: PMC327149 From the Cover:
The presenilins turned inside out: Implications for their structures and functions Nazneen N. Dewji, Dante Valdez, and S. J. Singer PMCID: PMC327150 From the Cover:
Paired-pulse depression of unitary quantal amplitude at single hippocampal synapses Gong Chen, Nobutoshi C. Harata, and Richard W. Tsien PMCID: PMC327151 A feedback mechanism regulates monoallelic odorant receptor expression Joseph W. Lewcock and Randall R. Reed PMCID: PMC327152 Increased soluble amyloid-β peptide and memory deficits in amyloid model mice overexpressing the low-density lipoprotein receptor-related protein Celina V. Zerbinatti, David F. Wozniak, John Cirrito, Judy A. Cam, Hiroshi Osaka, Kelly R. Bales, Min Zhuo, Steven M. Paul, David M. Holtzman, and Guojun Bu PMCID: PMC327153 Global optimization of cerebral cortex layout Christopher Cherniak, Zekeria Mokhtarzada, Raul Rodriguez-Esteban, and Kelly Changizi PMCID: PMC327154 Pharmacology Molecular basis for the inhibition of G protein-coupled inward rectifier K+ channels by protein kinase C Jinzhe Mao, Xueren Wang, Fuxue Chen, Runping Wang, Asheebo Rojas, Yun Shi, Hailan Piao, and Chun Jiang PMCID: PMC327155 Plant Biology INAUGURAL ARTICLE by a Recently Elected Academy Member: Biography of June B. Nasrallah Christen Brownlee PMCID: PMC330090 INAUGURAL ARTICLE by a Recently Elected Academy Member: Specificity determinants and diversification of the Brassica self-incompatibility pollen ligand Thanat Chookajorn, Aardra Kachroo, Daniel R. Ripoll, Andrew G. Clark, and June B. Nasrallah PMCID: PMC327116 Evidence for complex, collective dynamics and emergent, distributed computation in plants David Peak, Jevin D. West, Susanna M. Messinger, and Keith A. Mott PMCID: PMC327117 The Arabidopsis double-stranded RNA-binding protein HYL1 plays a role in microRNA-mediated gene regulation Meng-Hsuan Han, Saiprasad Goud, Liang Song, and Nina Fedoroff PMCID: PMC327156 Complementation of phytochrome chromophore-deficient Arabidopsis by expression of phycocyanobilin:ferredoxin oxidoreductase Chitose Kami, Keiko Mukougawa, Takuya Muramoto, Akiho Yokota, Tomoko Shinomura, J. Clark Lagarias, and Takayuki Kohchi PMCID: PMC327157 Psychology A subterranean mammal uses the magnetic compass for path integration Tali Kimchi, Ariane S. Etienne, and Joseph Terkel PMCID: PMC327158 Correction Proc Natl Acad Sci U S A. 2004 January 27; 101(4): 1110. doi: 10.1073/pnas.0307417100.PMCID: PMC327159 Corrects: León Patricio Martínez-Castilla, et al. Adaptive evolution in the Arabidopsis MADS-box gene family inferred from its complete resolved phylogeny. Proc Natl Acad Sci U S A. 2003 November 11; 100(23): 13407–13412. |
