| | This journal provides immediate access to some articles. Editorial Supplementary Material Can Now Appear Online Nicholas R. Cozzarelli Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12073. PMCID: PMC33902 Commentaries A role for the β-amyloid precursor protein in memory? Sangram S. Sisodia and Michela Gallagher Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12074–12076. PMCID: PMC33903 Cell death throes Suzanne Cory Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12077–12079. PMCID: PMC33904 Identifying the genes of hearing, deafness, and dysequilibrium Jeffrey T. Corwin Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12080–12082. PMCID: PMC33905 Physical Sciences Applied Physical Sciences A peptide that inhibits hydroxyapatite growth is in an extended conformation on the crystal surface Joanna R. Long, John L. Dindot, Henry Zebroski, Suzanne Kiihne, Rutilio H. Clark, Allison A. Campbell, Patrick S. Stayton, and Gary P. Drobny Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12083–12087. PMCID: PMC22788 Chemistry From ab initio quantum mechanics to molecular neurobiology: A cation–π binding site in the nicotinic receptor Wenge Zhong, Justin P. Gallivan, Yinong Zhang, Lintong Li, Henry A. Lester, and Dennis A. Dougherty Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12088–12093. PMCID: PMC22789 Ionophores and receptors using cation-π interactions: Collarenes Hyuk Soon Choi, Seung Bum Suh, Seung Joo Cho, and Kwang S. Kim Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12094–12099. PMCID: PMC22790 Biological Sciences Agricultural Sciences Role of calpain in skeletal-muscle protein degradation Jing Huang and Neil E. Forsberg Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12100–12105. PMCID: PMC22791 Transgenic DNA integrated into the oat genome is frequently interspersed by host DNA Wojciech P. Pawlowski and David A. Somers Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12106–12110. PMCID: PMC22792 Biochemistry A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: Architecture of metabolic diversity Yongquan Xue, Lishan Zhao, Hung-wen Liu, and David H. Sherman Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12111–12116. PMCID: PMC22793 Inhibition of protease-resistant prion protein formation by porphyrins and phthalocyanines Winslow S. Caughey, Lynne D. Raymond, Motohiro Horiuchi, and Byron Caughey Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12117–12122. PMCID: PMC22794 Crystal structure of the BTB domain from PLZF K. Farid Ahmad, Christian K. Engel, and Gilbert G. Privé Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12123–12128. PMCID: PMC22795 Structure of the Ets-1 pointed domain and mitogen-activated protein kinase phosphorylation site Carolyn M. Slupsky, Lisa N. Gentile, Logan W. Donaldson, Cameron D. Mackereth, Jeffrey J. Seidel, Barbara J. Graves, and Lawrence P. McIntosh Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12129–12134. PMCID: PMC22796 The role of the ClpA chaperone in proteolysis by ClpAP Joel R. Hoskins, Marie Pak, Michael R. Maurizi, and Sue Wickner Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12135–12140. PMCID: PMC22797 Oligomerization domain-directed reassembly of active dihydrofolate reductase from rationally designed fragments Joelle N. Pelletier, F.-X. Campbell-Valois, and Stephen W. Michnick Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12141–12146. PMCID: PMC22798 Complex gangliosides are essential in spermatogenesis of mice: Possible roles in the transport of testosterone Kogo Takamiya, Akihito Yamamoto, Keiko Furukawa, Jinmin Zhao, Satoshi Fukumoto, Shuji Yamashiro, Masahiko Okada, Masashi Haraguchi, Masashi Shin, Masao Kishikawa, Hiroshi Shiku, Shinichi Aizawa, and Koichi Furukawa Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12147–12152. PMCID: PMC22799 The anti-angiogenic agent fumagillin covalently modifies a conserved active-site histidine in the Escherichia coli methionine aminopeptidase W. Todd Lowther, Debra A. McMillen, Allen M. Orville, and Brian W. Matthews Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12153–12157. PMCID: PMC22800 Polyadenylation of stable RNA precursors in vivo Zhongwei Li, Shilpa Pandit, and Murray P. Deutscher Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12158–12162. PMCID: PMC22801 GroEL-GroES-mediated protein folding requires an intact central cavity Jue D. Wang, Melissa D. Michelitsch, and Jonathan S. Weissman Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12163–12168. PMCID: PMC22802 Enhanced transcription factor access to arrays of histone H3/H4 tetramer DNA complexes in vitro: Implications for replication and transcription Christin Tse, Terace M. Fletcher, and Jeffrey C. Hansen Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12169–12173. PMCID: PMC22803 The helical domain of intestinal fatty acid binding protein is critical for collisional transfer of fatty acids to phospholipid membranes Betina Corsico, David P. Cistola, Carl Frieden, and Judith Storch Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12174–12178. PMCID: PMC22804 Peptide design by artificial neural networks and computer-based evolutionary search Gisbert Schneider, Wieland Schrödl, Gerd Wallukat, Johannes Müller, Eberhard Nissen, Wolfgang Rönspeck, Paul Wrede, and Rudolf Kunze Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12179–12184. PMCID: PMC22805 Natural trans-splicing in carnitine octanoyltransferase pre-mRNAs in rat liver Concha Caudevilla, Dolors Serra, Angel Miliar, Carles Codony, Guillermina Asins, Montserrat Bach, and Fausto G. Hegardt Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12185–12190. PMCID: PMC22806 Efficient recruitment of TFIIB and CBP-RNA polymerase II holoenzyme by an interferon-β enhanceosome in vitro Tae Kook Kim, Tae Hoon Kim, and Tom Maniatis Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12191–12196. PMCID: PMC22807 Identification of the binding site for Gqα on its effector Bruton’s tyrosine kinase Yong-Chao Ma and Xin-Yun Huang Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12197–12201. PMCID: PMC22808 Rsk-2 activity is necessary for epidermal growth factor-induced phosphorylation of CREB protein and transcription of c-fos gene Dario De Cesare, Sylvie Jacquot, André Hanauer, and Paolo Sassone-Corsi Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12202–12207. PMCID: PMC22809 Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction Göran Bertilsson, Jessica Heidrich, Kristian Svensson, Michael Åsman, Lena Jendeberg, Mona Sydow-Bäckman, Rolf Ohlsson, Hans Postlind, Patrik Blomquist, and Anders Berkenstam Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12208–12213. PMCID: PMC22810 Activation of microhelix charging by localized helix destabilization Rebecca W. Alexander, Brian E. Nordin, and Paul Schimmel Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12214–12219. PMCID: PMC22811 Pro-phenol oxidase activating proteinase from an insect, Manduca sexta: A bacteria-inducible protein similar to Drosophila easter Haobo Jiang, Yang Wang, and Michael R. Kanost Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12220–12225. PMCID: PMC22812 Mammalian capping enzyme binds RNA and uses protein tyrosine phosphatase mechanism Yingxia Wen, Zhenyu Yue, and Aaron J. Shatkin Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12226–12231. PMCID: PMC22813 Mass spectrometric evidence for the enzymatic mechanism of the depolymerization of heparin-like glycosaminoglycans by heparinase II Andrew J. Rhomberg, Zachary Shriver, Klaus Biemann, and Ram Sasisekharan Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12232–12237. PMCID: PMC22814 rRNA complementarity within mRNAs: A possible basis for mRNA-ribosome interactions and translational control Pedro Tranque, Michael C.-Y. Hu, Gerald M. Edelman, and Vincent P. Mauro Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12238–12243. PMCID: PMC22815 Identification of 5′-deoxyribose phosphate lyase activity in human DNA polymerase γ and its role in mitochondrial base excision repair in vitro Matthew J. Longley, Rajendra Prasad, Deepak K. Srivastava, Samuel H. Wilson, and William C. Copeland Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12244–12248. PMCID: PMC22816 Requirement of GM2 ganglioside activator for phospholipase D activation Shun-ichi Nakamura, Toshihiro Akisue, Hitoshi Jinnai, Tomohiro Hitomi, Sukumar Sarkar, Noriko Miwa, Taro Okada, Kimihisa Yoshida, Shun’ichi Kuroda, Ushio Kikkawa, and Yasutomi Nishizuka Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12249–12253. PMCID: PMC22817 Activity and nature of p21WAF1 complexes during the cell cycle Kang Cai and Brian David Dynlacht Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12254–12259. PMCID: PMC22818 Identification of thyroid hormone response elements in the human fatty acid synthase promoter Shunbin Xiong, Subrahmanyam S. Chirala, Matthew H. Hsu, and Salih J. Wakil Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12260–12265. PMCID: PMC22819 Single prenyl-binding site on protein prenyl transferases Luc Desnoyers and Miguel C. Seabra Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12266–12270. PMCID: PMC22820 Biophysics Structural changes in hemoglobin during adsorption to solid surfaces: Effects of pH, ionic strength, and ligand binding Fredrik Höök, Michael Rodahl, Bengt Kasemo, and Peter Brzezinski Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12271–12276. PMCID: PMC22821 Temperature dependence of amyloid β-protein fibrillization Yoko Kusumoto, Aleksey Lomakin, David B. Teplow, and George B. Benedek Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12277–12282. PMCID: PMC22822 Force-mediated kinetics of single P-selectin/ligand complexes observed by atomic force microscopy Jürgen Fritz, Andreas G. Katopodis, Frank Kolbinger, and Dario Anselmetti Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12283–12288. PMCID: PMC22823 The structure and organization within the membrane of the helices composing the pore-forming domain of Bacillus thuringiensis δ-endotoxin are consistent with an “umbrella-like” structure of the pore Ehud Gazit, Paolo La Rocca, Mark S. P. Sansom, and Yechiel Shai Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12289–12294. PMCID: PMC22824 RecA binding to a single double-stranded DNA molecule: A possible role of DNA conformational fluctuations J. F. Leger, J. Robert, L. Bourdieu, D. Chatenay, and J. F. Marko Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12295–12299. PMCID: PMC22825 Protein thermostability above 100°C: A key role for ionic interactions Costantino Vetriani, Dennis L. Maeder, Nicola Tolliday, Kitty S.-P. Yip, Timothy J. Stillman, K. Linda Britton, David W. Rice, Horst H. Klump, and Frank T. Robb Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12300–12305. PMCID: PMC22826 Low frequency vibrational modes in proteins: Changes induced by point-mutations in the protein-cofactor matrix of bacterial reaction centers Christian Rischel, Diane Spiedel, Justin P. Ridge, Michael R. Jones, Jacques Breton, Jean-Christophe Lambry, Jean-Louis Martin, and Marten H. Vos Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12306–12311. PMCID: PMC22827 Cell Biology PRIM: Proximity imaging of green fluorescent protein-tagged polypeptides Dino A. De Angelis, Gero Miesenböck, Boris V. Zemelman, and James E. Rothman Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12312–12316. PMCID: PMC22828 Normal hepatic glucose production in the absence of GLUT2 reveals an alternative pathway for glucose release from hepatocytes Marie-Thérèse Guillam, Rémy Burcelin, and Bernard Thorens Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12317–12321. PMCID: PMC22829 Regulation of endothelial monocyte-activating polypeptide II release by apoptosis Ulrike E. Knies, Heike A. Behrensdorf, Christopher A. Mitchell, Urban Deutsch, Werner Risau, Hannes C. A. Drexler, and Matthias Clauss Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12322–12327. PMCID: PMC22830 Subnuclear localization of the active variant surface glycoprotein gene expression site in Trypanosoma brucei Inês Chaves, Joost Zomerdijk, Anita Dirks-Mulder, Roeland W. Dirks, Anton K. Raap, and Piet Borst Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12328–12333. PMCID: PMC22831 A DNA damage and stress inducible G protein-coupled receptor blocks cells in G2/M Zhigang Weng, Anne-Catherine Fluckiger, Sazuku Nisitani, Matthew I. Wahl, Lu Q. Le, Charity A. Hunter, Anthony A. Fernal, Michelle M. Le Beau, and Owen N. Witte Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12334–12339. PMCID: PMC22832 GIPC, a PDZ domain containing protein, interacts specifically with the C terminus of RGS-GAIP Luc De Vries, Xiaojing Lou, Grace Zhao, Bin Zheng, and Marilyn Gist Farquhar Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12340–12345. PMCID: PMC22833 Phospholipase D activity is required for suppression of yeast phosphatidylinositol transfer protein defects Zhigang Xie, Min Fang, Marcos P. Rivas, Alexander J. Faulkner, Paul C. Sternweis, JoAnne Engebrecht, and Vytas A. Bankaitis Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12346–12351. PMCID: PMC22834 Nuclear-encoded proteins target to the plastid in Toxoplasma gondii and Plasmodium falciparum Ross F. Waller, Patrick J. Keeling, Robert G. K. Donald, Boris Striepen, Emanuela Handman, Naomi Lang-Unnasch, Alan F. Cowman, Gurdyal S. Besra, David S. Roos, and Geoffrey I. McFadden Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12352–12357. PMCID: PMC22835 Developmental Biology Inhibition of myogenesis by transforming growth factor β is density-dependent and related to the translocation of transcription factor MEF2 to the cytoplasm Luciana De Angelis, Serena Borghi, Roberta Melchionna, Libera Berghella, Miranda Baccarani-Contri, Flavia Parise, Stefano Ferrari, and Giulio Cossu Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12358–12363. PMCID: PMC22836 Isolation and characterization of mammalian homologs of the Drosophila gene glial cells missing Jaesang Kim, Bradley W. Jones, Christiane Zock, Zhoufeng Chen, Hai Wang, Corey S. Goodman, and David J. Anderson Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12364–12369. PMCID: PMC22837 Delayed embryonic lethality in mice lacking protein phosphatase 2A catalytic subunit Cα Jürgen Götz, Alphonse Probst, Elisabeth Ehler, Brian Hemmings, and Wilfried Kues Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12370–12375. PMCID: PMC22838 Evolution Loss of social behaviors by Myxococcus xanthus during evolution in an unstructured habitat Gregory J. Velicer, Lee Kroos, and Richard E. Lenski Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12376–12380. PMCID: PMC22839 Natural genetic exchange between Haemophilus and Neisseria: Intergeneric transfer of chromosomal genes between major human pathogens J. Simon Kroll, Kathryn E. Wilks, Jayne L. Farrant, and Paul R. Langford Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12381–12385. PMCID: PMC22840 Testing the Cambrian explosion hypothesis by using a molecular dating technique Lindell Bromham, Andrew Rambaut, Richard Fortey, Alan Cooper, and David Penny Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12386–12389. PMCID: PMC22841 INAUGURAL ARTICLE by a Recently Elected Academy Member: The optimization principle in phylogenetic analysis tends to give incorrect topologies when the number of nucleotides or amino acids used is small Masatoshi Nei, Sudhir Kumar, and Kei Takahashi Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12390–12397. PMCID: PMC22842 Evidence for balancing selection operating at the het-c heterokaryon incompatibility locus in a group of filamentous fungi Jennifer Wu, Sven J. Saupe, and N. Louise Glass Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12398–12403. PMCID: PMC22843 Genetics The Saccharomyces cerevisiae MLH3 gene functions in MSH3-dependent suppression of frameshift mutations Hernan Flores-Rozas and Richard D. Kolodner Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12404–12409. PMCID: PMC22844 A novel amplicon at 8p22–23 results in overexpression of cathepsin B in esophageal adenocarcinoma Steven J. Hughes, Thomas W. Glover, Xiao-Xiang Zhu, Rork Kuick, Didier Thoraval, Mark B. Orringer, David G. Beer, and Samir Hanash Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12410–12415. PMCID: PMC22845 INAUGURAL ARTICLE by a Recently Elected Academy Member: Linkage disequilibrium mapping in isolated populations: The example of Finland revisited Albert de la Chapelle and Fred A. Wright Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12416–12423. PMCID: PMC22846 INAUGURAL ARTICLE by a Recently Elected Academy Member: Apoptosis regulator Bcl-w is essential for spermatogenesis but appears otherwise redundant Cristin G. Print, Kate L. Loveland, Leonie Gibson, Terri Meehan, Anna Stylianou, Nigel Wreford, David de Kretser, Donald Metcalf, Frank Köntgen, Jerry M. Adams, and Suzanne Cory Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12424–12431. PMCID: PMC22847 Knock-out mutants from an En-1 mutagenized Arabidopsis thaliana population generate phenylpropanoid biosynthesis phenotypes Ellen Wisman, Ulrike Hartmann, Martin Sagasser, Elvira Baumann, Klaus Palme, Klaus Hahlbrock, Heinz Saedler, and Bernd Weisshaar Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12432–12437. PMCID: PMC22848 Orientation-dependent and sequence-specific expansions of CTG/CAG trinucleotide repeats in Saccharomyces cerevisiae Juan José Miret, Luis Pessoa-Brandão, and Robert S. Lahue Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12438–12443. PMCID: PMC22849 Cloning of inversion breakpoints in the Anopheles gambiae complex traces a transposable element at the inversion junction Kostas D. Mathiopoulos, Alessandra della Torre, Valentina Predazzi, Vincenzo Petrarca, and Mario Coluzzi Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12444–12449. PMCID: PMC22850 Discrimination of the closely related A and D genomes of the hexaploid oat Avena sativa L. Concha Linares, Esther Ferrer, and Araceli Fominaya Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12450–12455. PMCID: PMC22851 Riboregulation in Escherichia coli: DsrA RNA acts by RNA:RNA interactions at multiple loci Richard A. Lease, Michael E. Cusick, and Marlene Belfort Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12456–12461. PMCID: PMC22852 DsrA RNA regulates translation of RpoS message by an anti-antisense mechanism, independent of its action as an antisilencer of transcription Nadim Majdalani, Christofer Cunning, Darren Sledjeski, Tom Elliott, and Susan Gottesman Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12462–12467. PMCID: PMC22853 Induction of microsatellite instability by oxidative DNA damage Aimee L. Jackson, Ru Chen, and Lawrence A. Loeb Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12468–12473. PMCID: PMC22854 A novel multicomponent regulatory system mediates H2 sensing in Alcaligenes eutrophus Oliver Lenz and Bärbel Friedrich Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12474–12479. PMCID: PMC22855 Resistance to DNA fragmentation and chromatin condensation in mice lacking the DNA fragmentation factor 45 Jianhua Zhang, Xuesong Liu, David C. Scherer, Luc van Kaer, Xiaodong Wang, and Ming Xu Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12480–12485. PMCID: PMC22856 Rap1 protein regulates telomere turnover in yeast Anat Krauskopf and Elizabeth H. Blackburn Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12486–12491. PMCID: PMC22857 Immunology Major histocompatibility complex (MHC) class I KbDb −/− deficient mice possess functional CD8+ T cells and natural killer cells Yulia Vugmeyster, Rickard Glas, Béatrice Pérarnau, François A. Lemonnier, Herman Eisen, and Hidde Ploegh Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12492–12497. PMCID: PMC22858 Cell-cycle arrest and apoptosis hypersusceptibility as a consequence of Lck deficiency in nontransformed T lymphocytes Basel K. al-Ramadi, Hui Zhang, and Alfred L. M. Bothwell Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12498–12503. PMCID: PMC22859 Cleavage motifs of the yeast 20S proteasome β subunits deduced from digests of enolase 1 Alexander K. Nussbaum, Tobias P. Dick, Wieland Keilholz, Markus Schirle, Stefan Stevanović, Klaus Dietz, Wolfgang Heinemeyer, Michael Groll, Dieter H. Wolf, Robert Huber, Hans-Georg Rammensee, and Hansjörg Schild Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12504–12509. PMCID: PMC22860 Diversification, expression, and γδ T cell recognition of evolutionarily distant members of the MIC family of major histocompatibility complex class I-related molecules Alexander Steinle, Veronika Groh, and Thomas Spies Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12510–12515. PMCID: PMC22861 Gene therapy in allergic encephalomyelitis using myelin basic protein-specific T cells engineered to express latent transforming growth factor-β1 L. Z. Chen, G. M. Hochwald, C. Huang, G. Dakin, H. Tao, C. Cheng, W. J. Simmons, G. Dranoff, and G. J. Thorbecke Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12516–12521. PMCID: PMC22862 Kinetics of T cell receptor β, γ, and δ rearrangements during adult thymic development: T cell receptor rearrangements are present in CD44+CD25+ Pro-T thymocytes Myriam Capone, Richard D. Hockett, Jr., and Albert Zlotnik Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12522–12527. PMCID: PMC22863 Synthetic amino acid copolymers that bind to HLA-DR proteins and inhibit type II collagen-reactive T cell clones Masha Fridkis-Hareli, Edward F. Rosloniec, Lars Fugger, and Jack L. Strominger Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12528–12531. PMCID: PMC22864 Charge-dependent translocation of Bordetella pertussis adenylate cyclase toxin into eukaryotic cells: Implication for the in vivo delivery of CD8+ T cell epitopes into antigen-presenting cells G. Karimova, C. Fayolle, S. Gmira, A. Ullmann, C. Leclerc, and D. Ladant Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12532–12537. PMCID: PMC22865 Major histocompatibility complex class I-restricted T cells are required for all but the end stages of diabetes development in nonobese diabetic mice and use a prevalent T cell receptor α chain gene rearrangement Teresa P. DiLorenzo, Robert T. Graser, Toshiro Ono, Gregory J. Christianson, Harold D. Chapman, Derry C. Roopenian, Stanley G. Nathenson, and David V. Serreze Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12538–12543. PMCID: PMC22866 Neuropeptides, by direct interaction with T cells, induce cytokine secretion and break the commitment to a distinct T helper phenotype Mia Levite Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12544–12549. PMCID: PMC22867 Interleukin 18 stimulates HIV type 1 in monocytic cells Leland Shapiro, Adrian J. Puren, Hazel A. Barton, Daniela Novick, Robert L. Peskind, Robert Shenkar, Yong Gu, Michael S.-S. Su, and Charles A. Dinarello Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12550–12555. PMCID: PMC22868 CXCR4 and CD4 mediate a rapid CD95-independent cell death in CD4+ T cells Christina Berndt, Barbara Möpps, Sabine Angermüller, Peter Gierschik, and Peter H. Krammer Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12556–12561. PMCID: PMC22869 Crystal structure of Taq DNA polymerase in complex with an inhibitory Fab: The Fab is directed against an intermediate in the helix-coil dynamics of the enzyme R. Murali, D. J. Sharkey, J. L. Daiss, and H. M. Krishna Murthy Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12562–12567. PMCID: PMC22870 Medical Sciences Patterns of HIV-1 evolution in individuals with differing rates of CD4 T cell decline Richard B. Markham, Wei-Cinn Wang, Anton E. Weisstein, Zhe Wang, Alvaro Munoz, Alan Templeton, Joseph Margolick, David Vlahov, Thomas Quinn, Homayoon Farzadegan, and Xiao-Fang Yu Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12568–12573. PMCID: PMC22871 Mycobacterium avium complex augments macrophage HIV-1 production and increases CCR5 expression S. M. Wahl, T. Greenwell-Wild, G. Peng, H. Hale-Donze, T. M. Doherty, D. Mizel, and J. M. Orenstein Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12574–12579. PMCID: PMC22872 Doxycycline control of prion protein transgene expression modulates prion disease in mice Patrick Tremblay, Zeev Meiner, Maria Galou, Cornelia Heinrich, Chris Petromilli, Thomas Lisse, Juliana Cayetano, Marilyn Torchia, William Mobley, Hermann Bujard, Stephen J. DeArmond, and Stanley B. Prusiner Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12580–12585. PMCID: PMC22873 Overexpression of DNA polymerase β in cell results in a mutator phenotype and a decreased sensitivity to anticancer drugs Yvan Canitrot, Christophe Cazaux, Mathilde Fréchet, Khalil Bouayadi, Claire Lesca, Bernard Salles, and Jean-Sébastien Hoffmann Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12586–12590. PMCID: PMC22874 Fibrinogen deficiency reduces vascular accumulation of apolipoprotein(a) and development of atherosclerosis in apolipoprotein(a) transgenic mice Xing Jian Lou, Nataya W. Boonmark, Frank T. Horrigan, Jay L. Degen, and Richard M. Lawn Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12591–12595. PMCID: PMC22875 Down-regulation of transmembrane carbonic anhydrases in renal cell carcinoma cell lines by wild-type von Hippel-Lindau transgenes Sergey V. Ivanov, Igor Kuzmin, Ming-Hui Wei, Svetlana Pack, Laura Geil, Bruce E. Johnson, Eric J. Stanbridge, and Michael I. Lerman Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12596–12601. PMCID: PMC22876 Rates of ubiquitin conjugation increase when muscles atrophy, largely through activation of the N-end rule pathway Vered Solomon, Vickie Baracos, Pasha Sarraf, and Alfred L. Goldberg Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12602–12607. PMCID: PMC22877 Abrogation of the G2 cell cycle checkpoint associated with overexpression of HSIX1: A possible mechanism of breast carcinogenesis Heide L. Ford, Edith N. Kabingu, Edward A. Bump, George L. Mutter, and Arthur B. Pardee Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12608–12613. PMCID: PMC22878 Deficient DNA-ligase activity in the metabolic disease tyrosinemia type I Maria José Prieto-Alamo and Françoise Laval Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12614–12618. PMCID: PMC22879 Microbiology Natural genetic exchange between Haemophilus and Neisseria: Intergeneric transfer of chromosomal genes between major human pathogens J. Simon Kroll, Kathryn E. Wilks, Jayne L. Farrant, and Paul R. Langford Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12381–12385. PMCID: PMC22840 Free recombination within Helicobacter pylori Sebastian Suerbaum, John Maynard Smith, Khairun Bapumia, Giovanna Morelli, Noel H. Smith, Erdmute Kunstmann, Isabelle Dyrek, and Mark Achtman Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12619–12624. PMCID: PMC22880 Molecular characterization of the mycobacterial heparin-binding hemagglutinin, a mycobacterial adhesin Franco D. Menozzi, Rainer Bischoff, Emmanuelle Fort, Michael J. Brennan, and Camille Locht Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12625–12630. PMCID: PMC22881 Sequence motifs in adenoviral DNA block immune activation by stimulatory CpG motifs Arthur M. Krieg, Tong Wu, Risini Weeratna, Susan M. Efler, Laurie Love-Homan, Lin Yang, Ae-Kyung Yi, Dan Short, and Heather L. Davis Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12631–12636. PMCID: PMC22882 Detection of 400-year-old Yersinia pestis DNA in human dental pulp: An approach to the diagnosis of ancient septicemia Michel Drancourt, Gérard Aboudharam, Michel Signoli, Olivier Dutour, and Didier Raoult Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12637–12640. PMCID: PMC22883 Human milk lactoferrin inactivates two putative colonization factors expressed by Haemophilus influenzae Jiazhou Qiu, David R. Hendrixson, Edward N. Baker, Timothy F. Murphy, Joseph W. St. Geme, III, and Andrew G. Plaut Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12641–12646. PMCID: PMC22884 Neurobiology From ab initio quantum mechanics to molecular neurobiology: A cation–π binding site in the nicotinic receptor Wenge Zhong, Justin P. Gallivan, Yinong Zhang, Lintong Li, Henry A. Lester, and Dennis A. Dougherty Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12088–12093. PMCID: PMC22789 Echo-delay resolution in sonar images of the big brown bat, Eptesicus fuscus James A. Simmons, Michael J. Ferragamo, and Cynthia F. Moss Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12647–12652. PMCID: PMC22885 Selective loss of dopaminergic nigro-striatal neurons in brains of Atm-deficient mice Raya Eilam, Yakov Peter, Ari Elson, Galit Rotman, Yosef Shiloh, Yoram Groner, and Menahem Segal Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12653–12656. PMCID: PMC22886 Neural systems underlying learning and representation of global motion Lucia M. Vaina, John W. Belliveau, Eric B. des Roziers, and Thomas A. Zeffiro Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12657–12662. PMCID: PMC22887 INAUGURAL ARTICLE by a Recently Elected Academy Member: Experience-dependent corticofugal adjustment of midbrain frequency map in bat auditory system Enquan Gao and Nobuo Suga Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12663–12670. PMCID: PMC22888 Galanin regulates prolactin release and lactotroph proliferation David Wynick, Caroline J. Small, Andrea Bacon, Fiona E. Holmes, Michael Norman, Christopher J. Ormandy, Eser Kilic, Niall C. H. Kerr, Mohammad Ghatei, Frank Talamantes, Stephen R. Bloom, and Vassilis Pachnis Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12671–12676. PMCID: PMC22889 Omega images at the active zone may be endocytotic rather than exocytotic: Implications for the vesicle hypothesis of transmitter release Jane H. Koenig, Kageyuki Yamaoka, and Kazuo Ikeda Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12677–12682. PMCID: PMC22890 Memory-enhancing effects of secreted forms of the β-amyloid precursor protein in normal and amnestic mice H. Meziane, J.-C. Dodart, C. Mathis, S. Little, J. Clemens, S. M. Paul, and A. Ungerer Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12683–12688. PMCID: PMC22891 Activation of nicotinic receptor-induced postsynaptic responses to luteinizing hormone-releasing hormone in bullfrog sympathetic ganglia via a Na+-dependent mechanism Ying-Jun Cao and Yan-Yi Peng Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12689–12694. PMCID: PMC22892 Neural basis of an inherited speech and language disorder F. Vargha-Khadem, K. E. Watkins, C. J. Price, J. Ashburner, K. J. Alcock, A. Connelly, R. S. J. Frackowiak, K. J. Friston, M. E. Pembrey, M. Mishkin, D. G. Gadian, and R. E. Passingham Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12695–12700. PMCID: PMC22893 Pharmacology 20-Hydroxyeicosatetraenoic acid mediates calcium/calmodulin-dependent protein kinase II-induced mitogen-activated protein kinase activation in vascular smooth muscle cells M. M. Muthalif, I. F. Benter, N. Karzoun, S. Fatima, J. Harper, M. R. Uddin, and K. U. Malik Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12701–12706. PMCID: PMC22894 Physiology Mahogany (mg) stimulates feeding and increases basal metabolic rate independent of its suppression of agouti Daniela M. Dinulescu, Wei Fan, Bruce A. Boston, Kathleen McCall, M. Lynn Lamoreux, Karen J. Moore, Jill Montagno, and Roger D. Cone Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12707–12712. PMCID: PMC22895 Plant Biology Inactivation of the mitogen-activated protein kinase Mps1 from the rice blast fungus prevents penetration of host cells but allows activation of plant defense responses Jin-Rong Xu, Christopher J. Staiger, and John E. Hamer Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12713–12718. PMCID: PMC22896 Chlorophyll a oxygenase (CAO) is involved in chlorophyll b formation from chlorophyll a Ayumi Tanaka, Hisashi Ito, Ryouichi Tanaka, Nobuaki K. Tanaka, Kazuichi Yoshida, and Kiyotaka Okada Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12719–12723. PMCID: PMC22897 Ethylene-mediated phenotypic plasticity in root nodule development on Sesbania rostrata Manuel Fernández-López, Sofie Goormachtig, Mengsheng Gao, Wim D’Haeze, Marc Van Montagu, and Marcelle Holsters Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12724–12728. PMCID: PMC22898 Psychology A perceptual memory for low-contrast visual signals Yasuto Tanaka and Dov Sagi Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12729–12733. PMCID: PMC22899 Corrections Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12734. PMCID: PMC56073 Corrects: Matteo Lorito, et al. Genes from mycoparasitic fungi as a source for improving plant resistance to fungal pathogens. Proc Natl Acad Sci U S A. 1998 July 7; 95(14): 7860–7865. Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12734. PMCID: PMC56074 Corrects: Yoseph Ghendler, et al. Differential thymic selection outcomes stimulated by focal structural alteration in peptide/major histocompatibility complex ligands. Proc Natl Acad Sci U S A. 1998 August 18; 95(17): 10061–10066. Proc Natl Acad Sci U S A. 1998 October 13; 95(21): 12734. PMCID: PMC56075 Corrects: James N. Topper, et al. CREB binding protein is a required coactivator for Smad-dependent, transforming growth factor β transcriptional responses in endothelial cells. Proc Natl Acad Sci U S A. 1998 August 4; 95(16): 9506–9511. |