| | This journal provides immediate access to some articles. Colloquium Papers Geology, mineralogy, and human welfare Joseph V. Smith PMCID: PMC34273 Characterization of complex mineral assemblages: Implications for
contaminant transport and environmental remediation Paul M. Bertsch and John C. Seaman PMCID: PMC34274 Surface geochemistry of the clay minerals Garrison Sposito, Neal T. Skipper, Rebecca Sutton, Sung-ho Park, Alan K. Soper, and Jeffery A. Greathouse PMCID: PMC34275 Contaminant bioavailability in soils, sediments, and
aquatic environments Samuel J. Traina and Valérie Laperche PMCID: PMC34276 Airborne minerals and related aerosol particles: Effects on
climate and the environment Peter R. Buseck and Mihály Pósfai PMCID: PMC34277 Oceanic minerals: Their origin, nature of their environment,
and significance Miriam Kastner PMCID: PMC34278 Mineral surfaces and bioavailability of heavy metals: A
molecular-scale perspective Gordon E. Brown, Jr., Andrea L. Foster, and John D. Ostergren PMCID: PMC34279 Long-range transport of mineral dust in the global atmosphere:
Impact of African dust on the environment of the southeastern
United States Joseph M. Prospero PMCID: PMC34280 Biological impact on mineral dissolution: Application of the
lichen model to understanding mineral weathering in the rhizosphere Jillian F. Banfield, William W. Barker, Susan A. Welch, and Anne Taunton PMCID: PMC34281 A risk assessment for exposure to grunerite asbestos (amosite) in
an iron ore mine R. P. Nolan, A. M. Langer, and Richard Wilson PMCID: PMC34282 Potential effects of gas hydrate on human welfare Keith A. Kvenvolden PMCID: PMC34283 Health impacts of domestic coal use in China Robert B. Finkelman, Harvey E. Belkin, and Baoshan Zheng PMCID: PMC34284 Nuclear waste forms for actinides Rodney C. Ewing PMCID: PMC34285 Illite and hydrocarbon exploration David R. Pevear PMCID: PMC34286 Manganese oxide minerals: Crystal structures and economic and
environmental significance Jeffrey E. Post PMCID: PMC34287 Negative pH, efflorescent mineralogy, and consequences for
environmental restoration at the Iron Mountain Superfund
site, California D. Kirk Nordstrom and Charles N. Alpers PMCID: PMC34288 La roca magica: Uses of natural zeolites in agriculture and industry Frederick A. Mumpton PMCID: PMC34179 Synthetic zeolites and other microporous oxide molecular sieves John D. Sherman PMCID: PMC34289 Biochemical evolution III: Polymerization on organophilic
silica-rich surfaces, crystal–chemical modeling, formation of
first cells, and geological clues Joseph V. Smith, Frederick P. Arnold, Jr., Ian Parsons, and Martin R. Lee PMCID: PMC34290 From the Academy Keeping America Secure for the 21st Century PMCID: PMC34291 Commentaries The dual role of calcium: Pore blocker and modulator of gating Richard Horn PMCID: PMC34267 Oral tolerance with Copolymer 1 for the treatment of
multiple sclerosis Howard L. Weiner PMCID: PMC34268 Microbial polyketide synthases: More and more prolific C. Richard Hutchinson PMCID: PMC34269 Crisis intervention: The role of telomerase Arthur J. Lustig PMCID: PMC34270 Evolution of amyloid: What normal protein folding may tell us about
fibrillogenesis and disease Peter T. Lansbury, Jr. PMCID: PMC34271 Luminal loop of the ryanodine receptor: A pore-forming segment? David Balshaw, Ling Gao, and Gerhard Meissner PMCID: PMC34272 Physical Sciences Chemistry Probing cell-surface architecture through synthesis: An NMR-determined structural motif for tumor-associated mucins David H. Live, Lawrence J. Williams, Scott D. Kuduk, Jacob B. Schwarz, Peter W. Glunz, Xiao-Tao Chen, Dalibor Sames, R. Ajay Kumar, and Samuel J. Danishefsky PMCID: PMC22319 Helionitronium trication (NO2He3+) and helionitrosonium trication (HeNO3+) George A. Olah, G. K. Surya Prakash, and Golam Rasul PMCID: PMC22320 Phthalascidin, a synthetic antitumor agent with potency and mode of action comparable to ecteinascidin 743 Eduardo J. Martinez, Takashi Owa, Stuart L. Schreiber, and E. J. Corey PMCID: PMC22321 Physics Screw rotations and glide mirrors: Crystallography in Fourier space Anja König and N. David Mermin PMCID: PMC22322 Biological Sciences Applied Biological Sciences Design of highly specific cytotoxins by using trans-splicing ribozymes Brian G. Ayre, Uwe Köhler, Howard M. Goodman, and Jim Haseloff PMCID: PMC22323 A cytosine analog that confers enhanced potency to antisense oligonucleotides W. Michael Flanagan, John J. Wolf, Peter Olson, Debbie Grant, Kuei-Ying Lin, Richard W. Wagner, and Mark D. Matteucci PMCID: PMC22324 Biochemistry SMRTe, a silencing mediator for retinoid and thyroid hormone receptors-extended isoform that is more related to the nuclear receptor corepressor Eun-Ju Park, Daniel J. Schroen, Maozhou Yang, Hui Li, Li Li, and J. Don Chen PMCID: PMC22325 Deduction of consensus binding sequences on proteins that bind IIAGlc of the phosphoenolpyruvate:sugar phosphotransferase system by cysteine scanning mutagenesis of Escherichia coli lactose permease Melissa Sondej, Jianzhong Sun, Yeong-Jae Seok, H. Ronald Kaback, and Alan Peterkofsky PMCID: PMC22326 Crystal structure of human type II inosine monophosphate dehydrogenase: Implications for ligand binding and drug design Thomas D. Colby, Kristen Vanderveen, Michael D. Strickler, George D. Markham, and Barry M. Goldstein PMCID: PMC22327 Nitroreductase A is regulated as a member of the soxRS regulon of Escherichia coli Stefan I. Liochev, Alfred Hausladen, and Irwin Fridovich PMCID: PMC22328 Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand Hailing Hsu, David L. Lacey, Colin R. Dunstan, Irina Solovyev, Anne Colombero, Emma Timms, Hong-Lin Tan, Gary Elliott, Michael J. Kelley, Ildiko Sarosi, Ling Wang, Xing-Zhong Xia, Robin Elliott, Laura Chiu, Tabitha Black, Sheila Scully, Casey Capparelli, Sean Morony, Grant Shimamoto, Michael B. Bass, and William J. Boyle PMCID: PMC22329 Biochemical characterization of Wnt-Frizzled interactions using a soluble, biologically active vertebrate Wnt protein Jen-Chih Hsieh, Amir Rattner, Philip M. Smallwood, and Jeremy Nathans PMCID: PMC22330 Replication fork assembly at recombination intermediates is required for bacterial growth Joing Liu, Liewei Xu, Steven J. Sandler, and Kenneth J. Marians PMCID: PMC22331 The role of threonine 37 in flavin reactivity of the old yellow enzyme Dong Xu, Rahul M. Kohli, and Vincent Massey PMCID: PMC22332 Combinatorial protein engineering by incremental truncation Marc Ostermeier, Andrew E. Nixon, Jae Hoon Shim, and Stephen J. Benkovic PMCID: PMC22333 Rational design of a scytalone dehydratase-like enzyme using a structurally homologous protein scaffold Andrew E. Nixon, Steven M. Firestine, Frank G. Salinas, and Stephen J. Benkovic PMCID: PMC22334 Crystal structure of human p32, a doughnut-shaped acidic mitochondrial matrix protein Jianzhong Jiang, Ying Zhang, Adrian R. Krainer, and Rui-Ming Xu PMCID: PMC22335 Thermal adaptation analyzed by comparison of protein sequences from mesophilic and extremely thermophilic Methanococcus species Paul J. Haney, Jonathan H. Badger, Gerald L. Buldak, Claudia I. Reich, Carl R. Woese, and Gary J. Olsen PMCID: PMC22336 Engineering precision RNA molecular switches Garrett A. Soukup and Ronald R. Breaker PMCID: PMC22337 Designing conditions for in vitro formation of amyloid protofilaments and fibrils Fabrizio Chiti, Paul Webster, Niccolò Taddei, Anne Clark, Massimo Stefani, Giampietro Ramponi, and Christopher M. Dobson PMCID: PMC22338 Mutually compensatory mutations during evolution of the tetramerization domain of tumor suppressor p53 lead to impaired hetero-oligomerization Mauricio G. Mateu and Alan R. Fersht PMCID: PMC22339 Crystal structure of a thermostable type B DNA polymerase from Thermococcus gorgonarius Karl-Peter Hopfner, Andreas Eichinger, Richard A. Engh, Frank Laue, Waltraud Ankenbauer, Robert Huber, and Bernhard Angerer PMCID: PMC22340 Cytoplasmic RNA modulators of an inside-out signal-transduction cascade Michael Blind, Waldemar Kolanus, and Michael Famulok PMCID: PMC22341 Expression of Batis maritima methyl chloride transferase in Escherichia coli Xinhai Ni and Lowell P. Hager PMCID: PMC22342 Telomerase in kinetoplastid parasitic protozoa M. I. N. Cano, J. M. Dungan, N. Agabian, and E. H. Blackburn PMCID: PMC22343 Ectopic expression of the minimal whiE polyketide synthase generates a library of aromatic polyketides of diverse sizes and shapes Yuemao Shen, Pall Yoon, Tin-Wein Yu, Heinz G. Floss, David Hopwood, and Bradley S. Moore PMCID: PMC22344 The chemokine monocyte chemoattractant protein-1 induces functional responses through dimerization of its receptor CCR2 José Miguel Rodríguez-Frade, Antonio J. Vila-Coro, Ana Martín de Ana, Juan Pablo Albar, Carlos Martínez-A., and Mario Mellado PMCID: PMC22345 Uncoupling of transfer of the presequence and unfolding of the mature domain in precursor translocation across the mitochondrial outer membrane Takashi Kanamori, Shuh-ichi Nishikawa, Masato Nakai, Injae Shin, Peter G. Schultz, and Toshiya Endo PMCID: PMC22346 The inositol polyphosphate 4-phosphatase forms a complex with phosphatidylinositol 3-kinase in human platelet cytosol A. D. Munday, F. A. Norris, K. K. Caldwell, S. Brown, P. W. Majerus, and C. A. Mitchell PMCID: PMC22347 Disruption of estrogen signaling does not prevent progesterone action in the estrogen receptor α knockout mouse uterus Sylvia W. Curtis, James Clark, Page Myers, and Kenneth S. Korach PMCID: PMC22348 Factor-specific modulation of CREB-binding protein acetyltransferase activity Valentina Perissi, Jeremy S. Dasen, Riki Kurokawa, Zhiyong Wang, Edward Korzus, David W. Rose, Christopher K. Glass, and Michael G. Rosenfeld PMCID: PMC22349 Biophysics Molecular characteristics of fibroblast growth factor–fibroblast growth factor receptor–heparin-like glycosaminoglycan complex Ganesh Venkataraman, Rahul Raman, V. Sasisekharan, and Ram Sasisekharan PMCID: PMC22350 Spin-lattice relaxation of laser-polarized xenon in human blood Jan Wolber, Andrea Cherubini, Andrzej S. K. Dzik-Jurasz, Martin O. Leach, and Angelo Bifone PMCID: PMC22351 Single-pair fluorescence resonance energy transfer on freely diffusing molecules: Observation of Förster distance dependence and subpopulations Ashok A. Deniz, Maxime Dahan, Jocelyn R. Grunwell, Taekjip Ha, Ann E. Faulhaber, Daniel S. Chemla, Shimon Weiss, and Peter G. Schultz PMCID: PMC22352 Comparing in vitro, in situ, and in vivo experimental data in a three-dimensional model of mammalian cochlear mechanics Paul J. Kolston PMCID: PMC22353 Alanine is helix-stabilizing in both template-nucleated and standard peptide helices Carol A. Rohl, Wayne Fiori, and Robert L. Baldwin PMCID: PMC22354 In situ atomic force microscopy study of Alzheimer’s β-amyloid peptide on different substrates: New insights into mechanism of β-sheet formation Tomasz Kowalewski and David M. Holtzman PMCID: PMC22355 Mechanical and chemical unfolding of a single protein: A comparison Mariano Carrion-Vazquez, Andres F. Oberhauser, Susan B. Fowler, Piotr E. Marszalek, Sheldon E. Broedel, Jane Clarke, and Julio M. Fernandez PMCID: PMC22356 Cell Biology Suppression of breast cancer growth and metastasis by a serpin myoepithelium-derived serine proteinase inhibitor expressed in the mammary myoepithelial cells Guowei Xiao, Yiliang E. Liu, Reiner Gentz, Qingxiang A. Sang, Jian Ni, Itzhak D. Goldberg, and Y. Eric Shi PMCID: PMC22357 GADD45 induction of a G2/M cell cycle checkpoint Xin Wei Wang, Qimin Zhan, Jill D. Coursen, Mohammed A. Khan, H. Udo Kontny, Lijia Yu, M. Christine Hollander, Patrick M. O’Connor, Albert J. Fornace, Jr., and Curtis C. Harris PMCID: PMC22358 The β2-adrenergic receptor/βarrestin complex recruits the clathrin adaptor AP-2 during endocytosis Stéphane A. Laporte, Robert H. Oakley, Jie Zhang, Jason A. Holt, Stephen S. G. Ferguson, Marc G. Caron, and Larry S. Barak PMCID: PMC22359 Abnormal photoresponses and light-induced apoptosis in rods lacking rhodopsin kinase Ching-Kang Chen, Marie E. Burns, Maribeth Spencer, Gregory A. Niemi, Jeannie Chen, James B. Hurley, Denis A. Baylor, and Melvin I. Simon PMCID: PMC22360 Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening Jiyue Zhu, He Wang, J. Michael Bishop, and Elizabeth H. Blackburn PMCID: PMC22361 Import of DNA into mammalian nuclei by proteins originating from a plant pathogenic bacterium Alicja Ziemienowicz, Dirk Görlich, Erich Lanka, Barbara Hohn, and Luca Rossi PMCID: PMC22362 Raft association of SNAP receptors acting in apical trafficking in Madin–Darby canine kidney cells Frank Lafont, Paul Verkade, Thierry Galli, Christian Wimmer, Daniel Louvard, and Kai Simons PMCID: PMC22363 Scar, a WASp-related protein, activates nucleation of actin filaments by the Arp2/3 complex Laura M. Machesky, R. Dyche Mullins, Henry N. Higgs, Donald A. Kaiser, Laurent Blanchoin, Robin C. May, Margaret E. Hall, and Thomas D. Pollard PMCID: PMC22364 A human Cds1-related kinase that functions downstream of ATM protein in the cellular response to DNA damage Alexandra L. Brown, Chang-Hun Lee, Julie K. Schwarz, Nesanet Mitiku, Helen Piwnica-Worms, and Jay H. Chung PMCID: PMC22365 Specific interaction of the yeast cis-Golgi syntaxin Sed5p and the coat protein complex II component Sec24p of endoplasmic reticulum-derived transport vesicles Renwang Peng, Reiner Grabowski, Anna De Antoni, and Dieter Gallwitz PMCID: PMC22366 Probing the Saccharomyces cerevisiae centromeric DNA (CEN DNA)–binding factor 3 (CBF3) kinetochore complex by using atomic force microscopy Lía I. Pietrasanta, Douglas Thrower, Wan Hsieh, Shashirekha Rao, Olaf Stemmann, Johannes Lechner, John Carbon, and Helen Hansma PMCID: PMC22367 Requirement of mitogen-activated protein kinase kinase 3 (MKK3) for tumor necrosis factor-induced cytokine expression Mark Wysk, Derek D. Yang, Hong-Tao Lu, Richard A. Flavell, and Roger J. Davis PMCID: PMC22368 Regulation of p53 expression by thymidylate synthase Jingfang Ju, Joan Pedersen-Lane, Frank Maley, and Edward Chu PMCID: PMC22369 Deletion of the loop region of Bcl-2 completely blocks paclitaxel-induced apoptosis Rakesh K. Srivastava, Qing-Sheng Mi, J. Marie Hardwick, and Dan L. Longo PMCID: PMC22370 Developmental Biology Requirement for the c-Maf transcription factor in crystallin gene regulation and lens development James I. Kim, Tiansen Li, I.-Cheng Ho, Michael J. Grusby, and Laurie H. Glimcher PMCID: PMC22371 The anterior determinant bicoid of Drosophila is a derived Hox class 3 gene Michael Stauber, Herbert Jäckle, and Urs Schmidt-Ott PMCID: PMC22372 Morphogenetic movements at gastrulation require the SH2 tyrosine phosphatase Shp2 Tracy M. Saxton and Tony Pawson PMCID: PMC22373 Evolution Distribution of haplotypes from a chromosome 21 region distinguishes multiple prehistoric human migrations Li Jin, Peter A. Underhill, Vishal Doctor, Ronald W. Davis, Peidong Shen, L. Luca Cavalli-Sforza, and Peter J. Oefner PMCID: PMC22374 Horizontal gene transfer among genomes: The complexity hypothesis Ravi Jain, Maria C. Rivera, and James A. Lake PMCID: PMC22375 Genomic evolution during a 10,000-generation experiment with bacteria Dimitri Papadopoulos, Dominique Schneider, Jessica Meier-Eiss, Werner Arber, Richard E. Lenski, and Michel Blot PMCID: PMC22376 Evolution of microbial diversity during prolonged starvation Steven E. Finkel and Roberto Kolter PMCID: PMC22413 A modern human pattern of dental development in Lower Pleistocene hominids from Atapuerca-TD6 (Spain) J. M. Bermúdez de Castro, A. Rosas, E. Carbonell, M. E. Nicolás, J. Rodríguez, and J. L. Arsuaga PMCID: PMC22446 Genetics An exon that prevents transport of a mature mRNA Margaret A. MacMorris, Diego A. R. Zorio, and Thomas Blumenthal PMCID: PMC22377 Pathogenetic sequence for aneurysm revealed in mice underexpressing fibrillin-1 Lygia Pereira, Sui Ying Lee, Barbara Gayraud, Kostantinos Andrikopoulos, Steven D. Shapiro, Tracie Bunton, Nancy Jensen Biery, Harry C. Dietz, Lynn Y. Sakai, and Francesco Ramirez PMCID: PMC22378 DRC1, DNA replication and checkpoint protein 1, functions with DPB11 to control DNA replication and the S-phase checkpoint in Saccharomyces cerevisiae Hong Wang and Stephen J. Elledge PMCID: PMC22379 A cluster of oppositely imprinted transcripts at the Gnas locus in the distal imprinting region of mouse chromosome 2 Jo Peters, Stephanie F. Wroe, Christine A. Wells, Howard J. Miller, Dorothy Bodle, Colin V. Beechey, Christine M. Williamson, and Gavin Kelsey PMCID: PMC22380 Genetic analysis of the mouse X inactivation center defines an 80-kb multifunction domain Jeannie T. Lee, Naifung Lu, and Yoon Han PMCID: PMC22381 Cladistic association analysis of Y chromosome effects on alcohol dependence and related personality traits Rick A. Kittles, Jeffrey C. Long, Andrew W. Bergen, Monica Eggert, Matti Virkkunen, Markku Linnoila, and David Goldman PMCID: PMC22445 Immunology Immunomodulation of experimental autoimmune encephalomyelitis by oral administration of copolymer 1 Dvora Teitelbaum, Ruth Arnon, and Michael Sela PMCID: PMC22382 HLA alleles determine human T-lymphotropic virus-I (HTLV-I) proviral load and the risk of HTLV-I-associated myelopathy Katie J. M. Jeffery, Koichiro Usuku, Sarah E. Hall, Wataru Matsumoto, Graham P. Taylor, Jeanette Procter, Mike Bunce, Graham S. Ogg, Kenneth I. Welsh, Jonathan N. Weber, Alun L. Lloyd, Martin A. Nowak, Masahiro Nagai, Daisuke Kodama, Shuji Izumo, Mitsuhiro Osame, and Charles R. M. Bangham PMCID: PMC22383 Ontogeny of T cell tolerance to peripherally expressed antigens David J. Morgan, Christian Kurts, Huub T. C. Kreuwel, Karen L. Holst, William R. Heath, and Linda A. Sherman PMCID: PMC22384 Ubiquitin-dependent degradation of IκBα is mediated by a ubiquitin ligase Skp1/Cul 1/F-box protein FWD1 Shigetsugu Hatakeyama, Masatoshi Kitagawa, Keiko Nakayama, Michiko Shirane, Masaki Matsumoto, Kimihiko Hattori, Hideaki Higashi, Hiroyasu Nakano, Ko Okumura, Kazunori Onoé, Robert A. Good, and Kei-ichi Nakayama PMCID: PMC22385 Crystal structure of the HLA-Cw3 allotype-specific killer cell inhibitory receptor KIR2DL2 Greg A. Snyder, Andrew G. Brooks, and Peter D. Sun PMCID: PMC22386 Characterization of inhibitory and stimulatory forms of the murine natural killer cell receptor 2B4 John D. Schatzle, Shane Sheu, Susan E. Stepp, Porunelloor A. Mathew, Michael Bennett, and Vinay Kumar PMCID: PMC22387 The p42 variant of ETS1 protein rescues defective Fas-induced apoptosis in colon carcinoma cells Runzhao Li, Huiping Pei, and Takis Papas PMCID: PMC22388 Regulation of T cell receptor (TCR) β gene expression by CD3 complex signaling in immature thymocytes: Implications for TCRβ allelic exclusion Judit Biro, Andreas Würch, Alexandre J. Potocnik, Ingrid Falk, Horst Mossmann, and Klaus Eichmann PMCID: PMC22389 The Ets transcription factor ERM is Th1-specific and induced by IL-12 through a Stat4-dependent pathway Wenjun Ouyang, Nils G. Jacobson, Deepta Bhattacharya, James D. Gorham, Domenic Fenoglio, William C. Sha, Theresa L. Murphy, and Kenneth M. Murphy PMCID: PMC22390 A logical analysis of T cell activation and anergy Marcelle Kaufman, Fabienne Andris, and Oberdan Leo PMCID: PMC22391 Medical Sciences Choroid plexus epithelial expression of MDR1 P glycoprotein and multidrug resistance-associated protein contribute to the blood–cerebrospinal-fluid drug-permeability barrier Vallabhaneni V. Rao, Julie L. Dahlheimer, Mark E. Bardgett, Abraham Z. Snyder, Rick A. Finch, Alan C. Sartorelli, and David Piwnica-Worms PMCID: PMC22392 Sustained correction of bleeding disorder in hemophilia B mice by gene therapy Lili Wang, Kazuaki Takabe, Scott M. Bidlingmaier, Charles R. Ill, and Inder M. Verma PMCID: PMC22393 Msh2 status modulates both apoptosis and mutation frequency in the murine small intestine Neil J. Toft, Douglas J. Winton, Jane Kelly, Louise A. Howard, Marleen Dekker, Hein te Riele, Mark J. Arends, Andrew H. Wyllie, Geoffrey P. Margison, and Alan R. Clarke PMCID: PMC22394 RB-mediated suppression of spontaneous multiple neuroendocrine neoplasia and lung metastases in Rb+/− mice Alexander Yu. Nikitin, María I. Juárez-Pérez, Song Li, Leaf Huang, and Wen-Hwa Lee PMCID: PMC22395 Constitutive and regulated α-secretase cleavage of Alzheimer’s amyloid precursor protein by a disintegrin metalloprotease Sven Lammich, Elzbieta Kojro, Rolf Postina, Sandra Gilbert, Roland Pfeiffer, Marek Jasionowski, Christian Haass, and Falk Fahrenholz PMCID: PMC22396 The FEZ1 gene at chromosome 8p22 encodes a leucine-zipper protein, and its expression is altered in multiple human tumors Hideshi Ishii, Raffaele Baffa, Shin-Ichiro Numata, Yoshiki Murakumo, Shashi Rattan, Hiroshi Inoue, Masaki Mori, Vincenzo Fidanza, Hansjuerg Alder, and Carlo M. Croce PMCID: PMC22397 Specific association of the gene product of PKD2 with the TRPC1 channel Leonidas Tsiokas, Thierry Arnould, Chenwen Zhu, Emily Kim, Gerd Walz, and Vikas P. Sukhatme PMCID: PMC22398 Transient excess of MYC activity can elicit genomic instability and tumorigenesis Dean W. Felsher and J. Michael Bishop PMCID: PMC22399 Targeting Gβγ signaling in arterial vascular smooth muscle proliferation: A novel strategy to limit restenosis Guido Iaccarino, L. Ashley Smithwick, Robert J. Lefkowitz, and Walter J. Koch PMCID: PMC22400 Induction of solid tumor differentiation by the peroxisome proliferator-activated receptor-γ ligand troglitazone in patients with liposarcoma George D. Demetri, Christopher D. M. Fletcher, Elisabetta Mueller, Pasha Sarraf, Ryan Naujoks, Natalee Campbell, Bruce M. Spiegelman, and Samuel Singer PMCID: PMC22401 Evidence for a structural motif in toxins and interleukin-2 that may be responsible for binding to endothelial cells and initiating vascular leak syndrome Roxana Baluna, Josep Rizo, Brian E. Gordon, Victor Ghetie, and Ellen S. Vitetta PMCID: PMC22402 Loss of transformed phenotype in cancer cells by overexpression of the uteroglobin gene Zhongjian Zhang, Gopal C. Kundu, Dibyendu Panda, Asim K. Mandal, Giuditta Mantile-Selvaggi, Alessandro Peri, Chiun-Jye Yuan, and Anil B. Mukherjee PMCID: PMC22403 MED1, a novel human methyl-CpG-binding endonuclease, interacts with DNA mismatch repair protein MLH1 Alfonso Bellacosa, Lucia Cicchillitti, Filippo Schepis, Antonio Riccio, Anthony T. Yeung, Yoshihiro Matsumoto, Erica A. Golemis, Maurizio Genuardi, and Giovanni Neri PMCID: PMC22404 Blood pressure reduction and diabetes insipidus in transgenic rats deficient in brain angiotensinogen Martina Schinke, Ovidiu Baltatu, Manfred Böhm, Jörg Peters, Wolfgang Rascher, Giampiero Bricca, Andrea Lippoldt, Detlev Ganten, and Michael Bader PMCID: PMC22405 Hepatocyte gene therapy in a large animal: A neonatal bovine model of citrullinemia Brendan Lee, Julie A. Dennis, Peter J. Healy, Benjamin Mull, Lucio Pastore, Hung Yu, Estuardo Aguilar-Cordova, William O’Brien, Peter Reeds, and Arthur L. Beaudet PMCID: PMC22406 Ectopic expression of prion protein (PrP) in T lymphocytes or hepatocytes of PrP knockout mice is insufficient to sustain prion replication Alex J. Raeber, Andreas Sailer, Ivan Hegyi, Michael A. Klein, Thomas Rülicke, Marek Fischer, Sebastian Brandner, Adriano Aguzzi, and Charles Weissmann PMCID: PMC22407 Induction of ARF tumor suppressor gene expression and cell cycle arrest by transcription factor DMP1 Kazushi Inoue, Martine F. Roussel, and Charles J. Sherr PMCID: PMC22408 Estrogen receptor (ER) modulators each induce distinct conformational changes in ER α and ER β Lisa A. Paige, Dale J. Christensen, Hanne Grøn, John D. Norris, Elizabeth B. Gottlin, Karen M. Padilla, Ching-yi Chang, Lawrence M. Ballas, Paul T. Hamilton, Donald P. McDonnell, and Dana M. Fowlkes PMCID: PMC22409 Identification of the block in targeted retroviral-mediated gene transfer Yi Zhao, Lunjian Zhu, Sunyoung Lee, Ling Li, Eric Chang, Nay-Wei Soong, Dan Douer, and W. French Anderson PMCID: PMC22410 Microbiology A mutant of Mycobacterium smegmatis defective in the biosynthesis of mycolic acids accumulates meromycolates Jun Liu and Hiroshi Nikaido PMCID: PMC22411 The meningococcal PilT protein is required for induction of intimate attachment to epithelial cells following pilus-mediated adhesion Céline Pujol, Emmanuel Eugène, Michaël Marceau, and Xavier Nassif PMCID: PMC22412 Evolution of microbial diversity during prolonged starvation Steven E. Finkel and Roberto Kolter PMCID: PMC22413 Vibrio cholerae O1 El Tor: Identification of a gene cluster required for the rugose colony type, exopolysaccharide production, chlorine resistance, and biofilm formation Fitnat H. Yildiz and Gary K. Schoolnik PMCID: PMC22414 Neurobiology Segregating the functions of human hippocampus B. A. Strange, P. C. Fletcher, R. N. A. Henson, K. J. Friston, and R. J. Dolan PMCID: PMC22415 Functional identification and reconstitution of an odorant receptor in single olfactory neurons Kazushige Touhara, Shintaro Sengoku, Koichiro Inaki, Akio Tsuboi, Junzo Hirono, Takaaki Sato, Hitoshi Sakano, and Tatsuya Haga PMCID: PMC22416 Natural and experimental oral infection of nonhuman primates by bovine spongiform encephalopathy agents Nöelle Bons, Nadine Mestre-Frances, Patrick Belli, Françoise Cathala, D. Carleton Gajdusek, and Paul Brown PMCID: PMC22417 Shift in speed selectivity of visual cortical neurons: A neural basis of perceived motion contrast Chao-Yi Li, Jing-Jiang Lei, and Hai-Shan Yao PMCID: PMC22418 Optical imaging of functional domains in the cortex of the awake and behaving monkey Norbert Vnek, Benjamin M. Ramsden, Chou P. Hung, Patricia S. Goldman-Rakic, and Anna Wang Roe PMCID: PMC22419 Evidence of a role for cyclic ADP-ribose in long-term synaptic depression in hippocampus Magali Reyes-Harde, Ruth Empson, Barry V. L. Potter, Antony Galione, and Patric K. Stanton PMCID: PMC22420 A nerve growth factor mimetic TrkA antagonist causes withdrawal of cortical cholinergic boutons in the adult rat Thomas Debeir, H. Uri Saragovi, and A. Claudio Cuello PMCID: PMC22421 Ephrin-dependent growth and pruning of hippocampal axons Pan-Pan Gao, Yong Yue, Douglas Pat Cerretti, Cheryl Dreyfus, and Renping Zhou PMCID: PMC22422 Herpes simplex virus vector-mediated expression of Bcl-2 prevents 6-hydroxydopamine-induced degeneration of neurons in the substantia nigra in vivo Masanobu Yamada, Thomas Oligino, Marina Mata, James R. Goss, Joseph C. Glorioso, and David J. Fink PMCID: PMC22423 Gene disruption of p27Kip1 allows cell proliferation in the postnatal and adult organ of Corti Hubert Löwenheim, David N. Furness, Jonathan Kil, Christoph Zinn, Karina Gültig, Matthew L. Fero, Deanna Frost, Anthony W. Gummer, James M. Roberts, Edwin W. Rubel, Carole M. Hackney, and Hans-Peter Zenner PMCID: PMC22424 Adult brain retains the potential to generate oligodendroglial progenitors with extensive myelination capacity Su-Chun Zhang, Bin Ge, and Ian D. Duncan PMCID: PMC22425 Long-range signaling within growing neurites mediated by neurotrophin-3 Sunghoe Chang and Sergey V. Popov PMCID: PMC22426 Coordinate regulation of gonadotropin-releasing hormone neuronal firing patterns by cytosolic calcium and store depletion Fredrick Van Goor, Lazar Z. Krsmanovic, Kevin J. Catt, and Stanko S. Stojilkovic PMCID: PMC22427 Quantitative fine-structural analysis of olfactory cortical synapses T. Schikorski and C. F. Stevens PMCID: PMC22428 Modulation of nicotinic acetylcholine receptors by strychnine Jesús García-Colunga and Ricardo Miledi PMCID: PMC22429 Unusual phenotypic alteration of β amyloid precursor protein (βAPP) maturation by a new Val-715 → Met βAPP-770 mutation responsible for probable early-onset Alzheimer’s disease K. Ancolio, C. Dumanchin, H. Barelli, J. M. Warter, A. Brice, D. Campion, T. Frébourg, and F. Checler PMCID: PMC22430 Neurotrophic factors [activity-dependent neurotrophic factor (ADNF) and basic fibroblast growth factor (bFGF)] interrupt excitotoxic neurodegenerative cascades promoted by a PS1 mutation Qing Guo, Lois Sebastian, Bryce L. Sopher, Miles W. Miller, Gordon W. Glazner, Carol B. Ware, George M. Martin, and Mark P. Mattson PMCID: PMC22431 Overexpression of thioredoxin in transgenic mice attenuates focal ischemic brain damage Yasushi Takagi, Akira Mitsui, Akira Nishiyama, Kazuhiko Nozaki, Hiroshi Sono, Yasuhiro Gon, Nobuo Hashimoto, and Junji Yodoi PMCID: PMC22432 Molecular basis of fast inactivation in voltage and Ca2+-activated K+ channels: A transmembrane β-subunit homolog Martin Wallner, Pratap Meera, and Ligia Toro PMCID: PMC22433 Pharmacology Mapping the active site in vasoactive intestinal peptide to a core of four amino acids: Neuroprotective drug design I. Gozes, O. Perl, E. Giladi, A. Davidson, O. Ashur-Fabian, S. Rubinraut, and M. Fridkin PMCID: PMC22434 NADH-quinone oxidoreductase: PSST subunit couples electron transfer from iron–sulfur cluster N2 to quinone Franz Schuler, Takahiro Yano, Salvatore Di Bernardo, Takao Yagi, Victoria Yankovskaya, Thomas P. Singer, and John E. Casida PMCID: PMC22435 Physiology Calcium block of Na+ channels and its effect on
closing rate C. M. Armstrong and Gabriel Cota PMCID: PMC22436 Distinguishing surface effects of calcium ion from pore-occupancy effects in Na+ channels C. M. Armstrong PMCID: PMC22437 A mutation in the transmembrane/luminal domain of the ryanodine receptor is associated with abnormal Ca2+ release channel function and severe central core disease Patrick J. Lynch, Jiefei Tong, Mary Lehane, Alejandro Mallet, Linda Giblin, James J. A. Heffron, Pat Vaughan, Gildardo Zafra, David H. MacLennan, and Tommie V. McCarthy PMCID: PMC22438 A single point mutation in the pore region of the epithelial Na+ channel changes ion selectivity by modifying molecular sieving Stephan Kellenberger, Ivan Gautschi, and Laurent Schild PMCID: PMC22439 Plant Biology Loss of the circadian clock-associated protein 1 in Arabidopsis results in altered clock-regulated gene expression R. M. Green and E. M. Tobin PMCID: PMC22440 Characterization of maize (Zea mays L.) Wee1 and its activity in developing endosperm Yuejin Sun, Brian P. Dilkes, Chunsheng Zhang, Ricardo A. Dante, Newton P. Carneiro, Keith S. Lowe, Rudolf Jung, William J. Gordon-Kamm, and Brian A. Larkins PMCID: PMC22441 Control of fertilization-independent endosperm development by the MEDEA polycomb gene in Arabidopsis Tomohiro Kiyosue, Nir Ohad, Ramin Yadegari, Mike Hannon, Jose Dinneny, Derek Wells, Anat Katz, Linda Margossian, John J. Harada, Robert B. Goldberg, and Robert L. Fischer PMCID: PMC22442 Conversion of cucumber linoleate 13-lipoxygenase to a 9-lipoxygenating species by site-directed mutagenesis Ellen Hornung, Matthias Walther, Hartmut Kühn, and Ivo Feussner PMCID: PMC22443 Genetic evidence for the role of GDP-mannose in plant ascorbic acid (vitamin C) biosynthesis Patricia L. Conklin, Susan R. Norris, Glen L. Wheeler, Elizabeth H. Williams, Nicholas Smirnoff, and Robert L. Last PMCID: PMC22444 Social Sciences Anthropology Distribution of haplotypes from a chromosome 21 region distinguishes multiple prehistoric human migrations Li Jin, Peter A. Underhill, Vishal Doctor, Ronald W. Davis, Peidong Shen, L. Luca Cavalli-Sforza, and Peter J. Oefner PMCID: PMC22374 Cladistic association analysis of Y chromosome effects on alcohol dependence and related personality traits Rick A. Kittles, Jeffrey C. Long, Andrew W. Bergen, Monica Eggert, Matti Virkkunen, Markku Linnoila, and David Goldman PMCID: PMC22445 A modern human pattern of dental development in Lower Pleistocene hominids from Atapuerca-TD6 (Spain) J. M. Bermúdez de Castro, A. Rosas, E. Carbonell, M. E. Nicolás, J. Rodríguez, and J. L. Arsuaga PMCID: PMC22446 Corrections Proc Natl Acad Sci U S A. 1999 March 30; 96(7): 4214. PMCID: PMC56058 Corrects: Terunaga Nakagawa, et al. Identification and classification of 16 new kinesin superfamily (KIF) proteins in mouse genome. Proc Natl Acad Sci U S A. 1997 September 2; 94(18): 9654–9659. Proc Natl Acad Sci U S A. 1999 March 30; 96(7): 4214. PMCID: PMC56059 Corrects: Artur W. Wamil, et al. CM101-mediated recovery of walking ability in adult mice paralyzed by spinal cord injury. Proc Natl Acad Sci U S A. 1998 October 27; 95(22): 13188–13193. |
