| | This journal provides immediate access to some articles. Commentary Les liaisons dangereuses: Adhesion molecules do it  statistically Robijn Bruinsma PMCID: PMC34134 Review The dynamins: Redundant or distinct functions for an expanding family of related GTPases? Raul Urrutia, John R. Henley, Tiffany Cook, and Mark A. McNiven PMCID: PMC34135 Biological Sciences Applied Biological Sciences Identification of the proteins of the yeast U1 small nuclear ribonucleoprotein complex by mass spectrometry Gitte Neubauer, Alexander Gottschalk, Patrizia Fabrizio, Bertrand Séraphin, Reinhard Lührmann, and Matthias Mann PMCID: PMC19520 Biochemistry Discrimination of a single base change in a ribozyme using the gene for dihydrofolate reductase as a selective marker in EscherichiacoliSatoshi Fujita, Tetsuhiko Koguma, Jun Ohkawa, Kazuyuki Mori, Takeo Kohda, Hideo Kise, Satoshi Nishikawa, Masahiro Iwakura, and Kazunari Taira PMCID: PMC19521 Cloning of a trypanosomatid gene coding for an ornithine decarboxylase that is metabolically unstable even though it lacks the C-terminal degradation domain Fredrik Svensson, Carolina Ceriani, Eva Lövkvist Wallström, Inger Kockum, Israel D. Algranati, Olle Heby, and Lo Persson PMCID: PMC19522 Differential behavior of curved DNA upon untwisting Ivan Brukner, Abdellah Belmaaza, and Pierre Chartrand PMCID: PMC19523 Conferring RNA polymerase Activity to a DNA polymerase: A single residue in reverse transcriptase controls substrate selection Guangxia Gao, Marianna Orlova, Millie M. Georgiadis, Wayne A. Hendrickson, and Stephen P. Goff PMCID: PMC19524 In vitro scanning saturation mutagenesis of an antibody binding pocket Elizabeth A. Burks, Gang Chen, George Georgiou, and Brent L. Iverson PMCID: PMC19525 Fetal mouse selenophosphate synthetase 2 (SPS2): Characterization of the cysteine mutant form overproduced in a baculovirus–insect cell system Ick Young Kim, M. Jorge Guimarães, Albert Zlotnik, J. Fernando Bazan, and Thressa C. Stadtman PMCID: PMC19526 rRNA-like sequences occur in diverse primary transcripts: Implications for the control of gene expression Vincent P. Mauro and Gerald M. Edelman PMCID: PMC19527 RGS4 and GAIP are GTPase-activating proteins for G qα and block activation of phospholipase Cβ by γ-thio-GTP-G qαJohn R. Hepler, David M. Berman, Alfred G. Gilman, and Tohru Kozasa PMCID: PMC19528 Drosophila TFIIE: Purification, cloning, and functional reconstitution Xia Wang, Stig K. Hansen, Ryan Ratts, Sharleen Zhou, Amy J. Snook, and William Zehring PMCID: PMC19529 Polyphosphate kinase as a nucleoside diphosphate kinase in Escherichia coli and PseudomonasaeruginosaAkio Kuroda and Arthur Kornberg PMCID: PMC19530 A point mutation leads to altered product specificity in β-lactamase catalysis Evan R. Lewis, Kelly M. Winterberg, and Anthony L. Fink PMCID: PMC19531 Cell cycle arrest mediated by the MEK/mitogen-activated protein kinase pathway Kevin M. Pumiglia and Stuart J. Decker PMCID: PMC19532 Major proteinase movement upon stable serpin–proteinase complex formation Efstratios Stratikos and Peter G. W. Gettins PMCID: PMC19533 A mutation of the atrial natriuretic peptide (guanylyl cyclase-A) receptor results in a constitutively hyperactive enzyme Barbara J. Wedel, David C. Foster, Deborah E. Miller, and David L. Garbers PMCID: PMC19534 Activities of human recombination protein Rad51 Ravindra C. Gupta, L. Rochelle Bazemore, Efim I. Golub, and Charles M. Radding PMCID: PMC19535 The human A33 antigen is a transmembrane glycoprotein and a novel member of the immunoglobulin superfamily Joan K. Heath, Sara J. White, Cameron N. Johnstone, Bruno Catimel, Richard J. Simpson, Robert L. Moritz, Guo-Fen Tu, Hong Ji, Robert H. Whitehead, Leo C. Groenen, Andrew M. Scott, Gerd Ritter, Leonard Cohen, Sydney Welt, Lloyd J. Old, Edouard C. Nice, and Antony W. Burgess PMCID: PMC19536 Ribonucleotide reductase in the archaeon Pyrococcus furiosus: A critical enzyme in the evolution of DNA genomes? Joan Riera, Frank T. Robb, Robert Weiss, and Marc Fontecave PMCID: PMC19537 The thioredoxin binding domain of bacteriophage T7 DNA polymerase confers processivity on Escherichia coli DNA polymerase I Ella Bedford, Stanley Tabor, and Charles C. Richardson PMCID: PMC19538 Probing the environment along the protein import pathways in yeast mitochondria by site-specific photocrosslinking Takashi Kanamori, Shuh-Ichi Nishikawa, Injae Shin, Peter G. Schultz, and Toshiya Endo PMCID: PMC19539 Biophysics The role of phenylalanine in structure–function relationships of phenylalanine hydroxylase revealed by radiation target analysis Michael D. Davis, Michael A. Parniak, Seymour Kaufman, and Ellis Kempner PMCID: PMC19540 Visualization of supercoiled DNA with atomic force microscopy insituYuri L. Lyubchenko and Luda S. Shlyakhtenko PMCID: PMC19541 Cell Biology Nuclear localization of cyclin B1 mediates its biological activity and is regulated by phosphorylation Jianke Li, April N. Meyer, and Daniel J. Donoghue PMCID: PMC19542 The N-terminal propiece of interleukin 1α is a transforming nuclear oncoprotein Frazier T. Stevenson, Johanna Turck, Richard M. Locksley, and David H. Lovett PMCID: PMC19543 Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress F. Michael Yakes and Bennett Van Houten PMCID: PMC19544 Membrane specific mapping and colocalization of malarial and host skeletal proteins in the Plasmodium falciparum infected erythrocyte by dual-color near-field scanning optical microscopy Th. Enderle, T. Ha, D. F. Ogletree, D. S. Chemla, C. Magowan, and S. Weiss PMCID: PMC19545 A p53-independent damage-sensing mechanism that functions as a checkpoint at the G 1/S transition in Chinese hamster ovary cells Hoyun Lee, James M. Larner, and Joyce L. Hamlin PMCID: PMC19546 Activation of human B-MYB by cyclins Arturo Sala, Mondira Kundu, Ida Casella, Andrew Engelhard, Bruno Calabretta, Luigi Grasso, Marco G. Paggi, Antonio Giordano, Roger J. Watson, Kamel Khalili, and Cesare Peschle PMCID: PMC19547 Mitosis-promoting factor-mediated suppression of a cloned delayed rectifier potassium channel expressed in Xenopusoocytes Andrea Brüggemann, Walter Stühmer, and Luis A. Pardo PMCID: PMC19548 Developmental Biology Effects of methionine on the cytoplasmic distribution of actin and tubulin during neural tube closure in rat embryos Shadrack R. Moephuli, Norman W. Klein, Michael T. Baldwin, and Hallie M. Krider PMCID: PMC19549 Evolution Immunocompetence, ornamentation, and viability of male barn swallows ( Hirundorustica) Nicola Saino, Anna Maria Bolzern, and Anders Pape Møller PMCID: PMC19550 Evolution of trans-splicing plant mitochondrial introns in pre-Permian times Olaf Malek, Axel Brennicke, and Volker Knoop PMCID: PMC19551 Genetics Inactivation of FtsI inhibits constriction of the FtsZ cytokinetic ring and delays the assembly of FtsZ rings at potential division sites Joe Pogliano, Kit Pogliano, David S. Weiss, Richard Losick, and Jon Beckwith PMCID: PMC19552 Identification of protein coding regions in the human genome by quadratic discriminant analysis M. Q. Zhang PMCID: PMC19553 Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein α-deficient mice Dong-Er Zhang, Pu Zhang, Nai-dy Wang, Christopher J. Hetherington, Gretchen J. Darlington, and Daniel G. Tenen PMCID: PMC19554 Characterization of the chicken β-globin insulator Jay H. Chung, Adam C. Bell, and Gary Felsenfeld PMCID: PMC19555 Role of the casein kinase I isoform, Hrr25, and the cell cycle-regulatory transcription factor, SBF, in the transcriptional response to DNA damage in SaccharomycescerevisiaeYuen Ho, Stephen Mason, Ryuji Kobayashi, Merl Hoekstra, and Brenda Andrews PMCID: PMC19556 Linkage of a neurophysiological deficit in schizophrenia to a chromosome 15 locus Robert Freedman, Hilary Coon, Marina Myles-Worsley, Avi Orr-Urtreger, Ann Olincy, Ashley Davis, Mihael Polymeropoulos, John Holik, Jan Hopkins, Mark Hoff, Judy Rosenthal, Merilyne C. Waldo, Fred Reimherr, Paul Wender, Jeffrey Yaw, David A. Young, Charles R. Breese, Catherine Adams, David Patterson, Lawrence E. Adler, Leonid Kruglyak, Sherry Leonard, and William Byerley PMCID: PMC19557 UV endonuclease of Micrococcus luteus, a cyclobutane pyrimidine dimer–DNA glycosylase/abasic lyase: Cloning and characterization of the gene Susumu Shiota and Hiroaki Nakayama PMCID: PMC19558 Immunology Increased interleukin 12 production in progressive multiple sclerosis: Induction by activated CD4 + T cells via CD40 ligand Konstantin E. Balashov, Derek R. Smith, Samia J. Khoury, David A. Hafler, and Howard L. Weiner PMCID: PMC19559 BAP-135, a target for Bruton’s tyrosine kinase in response to B cell receptor engagement Weiyi Yang and Stephen Desiderio PMCID: PMC19560 Correction of the X-linked immunodeficiency phenotype by transgenic expression of human Bruton tyrosine kinase under the control of the class II major histocompatibility complex Ea locus control region Dubravka Drabek, Selina Raguz, Ton P. M. De Wit, Gemma M. Dingjan, Huub F. J. Savelkoul, Frank Grosveld, and Rudolf W. Hendriks PMCID: PMC19561 Development and function of T cells in T cell antigen
receptor/CD3 ζ knockout mice reconstituted with Fc ![[var epsilon]](corehtml/pmc/pmcents/epsiv.gif) RI γ Chih-Pin Liu, Wei-Jen Lin, Manley Huang, John W. Kappler, and Philippa Marrack PMCID: PMC19562 Antigen organization regulates cluster formation and induction of cytotoxic T lymphocytes by helper T cell subsets Gernot Stuhler and Stuart F. Schlossman PMCID: PMC19563 Amino-terminal trimming of peptides for presentation on major histocompatibility complex class II molecules Christopher A. Nelson, Ilan Vidavsky, Nicholas J. Viner, Michael L. Gross, and Emil R. Unanue PMCID: PMC19564 Interferon-α/β inhibition of interleukin 12 and interferon-γ production in vitro and endogenously during viral infection Leslie P. Cousens, Jordan S. Orange, Helen C. Su, and Christine A. Biron PMCID: PMC19565 Protection against immunopathological consequences of a viral infection by activated but not resting cytotoxic T cells: T cell memory without “memory T cells”? Martin F. Bachmann, Thomas M. Kündig, Hans Hengartner, and Rolf M. Zinkernagel PMCID: PMC19566 Peripheral deletion of rheumatoid factor B cells after abortive activation by IgG Helen Tighe, Klaus Warnatz, Diana Brinson, Maripat Corr, William O. Weigle, Stephen M. Baird, and Dennis A. Carson PMCID: PMC19567 Medical Sciences Design, synthesis, and in vitro evaluation of cytotoxic analogs of bombesin-like peptides containing doxorubicin or its intensely potent derivative, 2-pyrrolinodoxorubicin Attila Nagy, Patricia Armatis, Ren-Zhi Cai, Karoly Szepeshazi, Gabor Halmos, and Andrew V. Schally PMCID: PMC19568 Epidermal growth factor receptor activation induces nuclear targeting of cyclooxygenase-2, basolateral release of prostaglandins, and mitogenesis in polarizing colon cancer cells Robert J. Coffey, Chris J. Hawkey, Lars Damstrup, Ramona Graves-Deal, Vincent C. Daniel, Peter J. Dempsey, Rebecca Chinery, Susan C. Kirkland, Raymond N. DuBois, Thomas L. Jetton, and Jason D. Morrow PMCID: PMC19569 Constitutive production and thrombin-induced release of vascular endothelial growth factor by human megakaryocytes and platelets Robert Möhle, David Green, Malcolm A. S. Moore, Ralph L. Nachman, and Shahin Rafii PMCID: PMC19570 Cancer-associated mutations at the INK4a locus cancel cell cycle arrest by p16 INK4a but not by the alternative reading frame protein p19 ARFDawn E. Quelle, Mangeng Cheng, Richard A. Ashmun, and Charles J. Sherr PMCID: PMC19571 Free radical oxidation of brain proteins in accelerated senescence and its modulation by N-tert-butyl-α-phenylnitrone D. Allan Butterfield, Beverly J. Howard, Servet Yatin, Kerry L. Allen, and John M. Carney PMCID: PMC19572 Inhibition of the activity of poly(ADP ribose) synthetase reduces ischemia–reperfusion injury in the heart and skeletal muscle Christoph Thiemermann, Joanne Bowes, Fiona P. Myint, and John R. Vane PMCID: PMC19573 Inhibition of tumorigenesis by a cytosine–DNA, methyltransferase, antisense oligodeoxynucleotide Shyam Ramchandani, A. Robert MacLeod, Marc Pinard, Eric von Hofe, and Moshe Szyf PMCID: PMC19574 A Bcl-2 homolog encoded by Kaposi sarcoma-associated virus, human herpesvirus 8, inhibits apoptosis but does not heterodimerize with Bax or Bak Emily H.-Y. Cheng, John Nicholas, David S. Bellows, Gary S. Hayward, Hong-Guang Guo, Marvin S. Reitz, and J. Marie Hardwick PMCID: PMC19575 Quantitative detection of immune activation transcripts as a diagnostic tool in kidney transplantation Jürgen Strehlau, Martha Pavlakis, Mark Lipman, Michael Shapiro, Lauro Vasconcellos, William Harmon, and Terry B. Strom PMCID: PMC19576 Diverse tumorigenesis associated with aberrant development in mice overexpressing hepatocyte growth factor/scatter factor Hisashi Takayama, William J. LaRochelle, Richard Sharp, Toshiyuki Otsuka, Paul Kriebel, Miriam Anver, Stuart A. Aaronson, and Glenn Merlino PMCID: PMC19577 Neurobiology Identification of a structural constituent and one possible site of postembryonic formation of a teleost otolithic membrane James G. Davis, Frank R. Burns, Dasakumar Navaratnam, A. Masaji Lee, Shingo Ichimiya, J. Carl Oberholtzer, and Mark I. Greene PMCID: PMC19578 Molecular characterization of two mammalian bHLH-PAS domain proteins selectively expressed in the central nervous system Yu-Dong Zhou, Mary Barnard, Hui Tian, Xu Li, Huijun Z. Ring, Uta Francke, John Shelton, James Richardson, David W. Russell, and Steven L. McKnight PMCID: PMC19579 The neural code between neocortical pyramidal neurons depends on neurotransmitter release probability Misha V. Tsodyks and Henry Markram PMCID: PMC19580 Dendritic calcium conductances generate high-frequency oscillation in thalamocortical neurons Christine Pedroarena and Rodolfo Llinás PMCID: PMC19581 Expression and regulation of the neuropeptide Y Y2 receptor in sensory and autonomic ganglia Xu Zhang, Tiejun Shi, Kristina Holmberg, Marc Landry, Wenjin Huang, Huasheng Xiao, Gong Ju, and Tomas Hökfelt PMCID: PMC19582 On the relationship between synaptic input and spike output jitter in individual neurons Petr Maršálek, Christof Koch, and John Maunsell PMCID: PMC19583 Regulation of microtubule dynamics by the neuronal growth-associated protein SCG10 Beat M. Riederer, Véronique Pellier, Bruno Antonsson, Gilbert Di Paolo, Stephen A. Stimpson, Robert Lütjens, Stefan Catsicas, and Gabriele Grenningloh PMCID: PMC19584 Pharmacology Inhibition of nuclear factor κB by prostaglandin A 1: An effect associated with heat shock transcription factor activation Antonio Rossi, Giuliano Elia, and M. Gabriella Santoro PMCID: PMC19585 Selective reconstitution of gastrin-releasing peptide receptor with Gα qMark R. Hellmich, James F. Battey, and John K. Northup PMCID: PMC19586 Physiology Failure to express the P-selectin gene or P-selectin blockade confers early pulmonary protection after lung ischemia or transplantation Yoshifumi Naka, Koichi Toda, Koichi Kayano, Mehmet C. Oz, and David J. Pinsky PMCID: PMC19587 Plant Biology A homolog of the mammalian GTPase Rab2 is present in Arabidopsis and is expressed predominantly in pollen grains and seedlings Ian Moore, Thomas Diefenthal, Viktor Zarsky, Jeff Schell, and Klaus Palme PMCID: PMC19588 |
