pmc logo imageJournal ListSearchpmc logo image
Logo of pnasPNAS Home page.PNAS Editorial BoardPNAS AboutPNAS SubscriptionsPNAS Info for Authors
This journal provides immediate access to some articles.
Other Issues:  previous | next | latest | archive
Volume 96(1);  January 5, 1999
Editorial
Redesign of PNAS: New Covers for the Journal
Diane M. Sullenberger, Kenneth R. Fulton, and Nicholas R. Cozzarelli
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 1.
PMCID: PMC33536
Commentaries
Transcriptional regulation: Contending with complexity
Frank C. P. Holstege and Richard A. Young
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 2–4.
PMCID: PMC33537
Why is Hu where? Shuttling of early-response-gene messenger RNA subsets
Jack D. Keene
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 5–7.
PMCID: PMC33538
Coevolutionary arms races: Is victory possible?
Peter Kareiva
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 8–10.
PMCID: PMC33539
Physical Sciences
Applied Physical Sciences
A microfabricated device for sizing and sorting DNA molecules
Hou-Pu Chou, Charles Spence, Axel Scherer, and Stephen Quake
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 11–13.
PMCID: PMC15083
Engineering
An arrayable flow-through microcentrifuge for high-throughput instrumentation
Andre Marziali, Thomas D. Willis, and Ronald W. Davis
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 61–66.
PMCID: PMC15093
Biological Sciences
Applied Biological Sciences
Enhancement of cellulose production by expression of sucrose synthase in Acetobacter xylinum
Tomonori Nakai, Naoto Tonouchi, Teruko Konishi, Yukiko Kojima, Takayasu Tsuchida, Fumihiro Yoshinaga, Fukumi Sakai, and Takahisa Hayashi
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 14–18.
PMCID: PMC15084
The oncogenic transforming potential of the passage of single α particles through mammalian cell nuclei
Richard C. Miller, Gerhard Randers-Pehrson, Charles R. Geard, Eric J. Hall, and David J. Brenner
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 19–22.
PMCID: PMC15085
Biochemistry
CIR, a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complex
James J.-D. Hsieh, Sifang Zhou, Lin Chen, David B. Young, and S. Diane Hayward
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 23–28.
PMCID: PMC15086
A change in actin conformation associated with filament instability after Pi release
Lisa D. Belmont, Albina Orlova, David G. Drubin, and Edward H. Egelman
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 29–34.
PMCID: PMC15087
Proton exit from the heme–copper oxidase of Escherichia coli
Anne Puustinen and Mårten Wikström
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 35–37.
PMCID: PMC15088
Mutagenesis of conserved lysine residues in bacteriophage T5 5′-3′ exonuclease suggests separate mechanisms of endoand exonucleolytic cleavage
Scott J. Garforth, Thomas A. Ceska, Dietrich Suck, and Jon R. Sayers
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 38–43.
PMCID: PMC15089
Catalytic properties of selenophosphate synthetases: Comparison of the selenocysteine-containing enzyme from Haemophilus influenzae with the corresponding cysteine-containing enzyme from Escherichia coli
Gerard M. Lacourciere and Thressa C. Stadtman
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 44–48.
PMCID: PMC15090
Mechanisms by which IκB proteins control NF-κB activity
Simos Simeonidis, Deborah Stauber, Guoying Chen, Wayne A. Hendrickson, and Dimitris Thanos
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 49–54.
PMCID: PMC15091
Homotypic interaction and multimerization of nucleocapsid protein of tomato spotted wilt tospovirus: Identification and characterization of two interacting domains
J. F. Uhrig, T.-R. Soellick, C. J. Minke, C. Philipp, J.-W. Kellmann, and P. H. Schreier
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 55–60.
PMCID: PMC15092
An arrayable flow-through microcentrifuge for high-throughput instrumentation
Andre Marziali, Thomas D. Willis, and Ronald W. Davis
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 61–66.
PMCID: PMC15093
Mediator protein mutations that selectively abolish activated transcription
Lawrence C. Myers, Claes M. Gustafsson, Kathleen C. Hayashibara, Patrick O. Brown, and Roger D. Kornberg
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 67–72.
PMCID: PMC15094
Mechanism of recruitment of DnaB helicase to the replication origin of the plasmid pSC101
Hirock J. Datta, Ghan Shyam Khatri, and Deepak Bastia
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 73–78.
PMCID: PMC15095
Cytosolic adenylyl cyclase defines a unique signaling molecule in mammals
Jochen Buck, Meeghan L. Sinclair, Lissy Schapal, Martin J. Cann, and Lonny R. Levin
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 79–84.
PMCID: PMC15096
Characterization of functionally active subribosomal particles from Thermus aquaticus
Philipp Khaitovich, Alexander S. Mankin, Rachel Green, Laura Lancaster, and Harry F. Noller
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 85–90.
PMCID: PMC15097
Gene delivery: A single nuclear localization signal peptide is sufficient to carry DNA to the cell nucleus
Maria Antonietta Zanta, Pascale Belguise-Valladier, and Jean-Paul Behr
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 91–96.
PMCID: PMC15098
Pneumocysterol [(24Z)-ethylidenelanost-8-en-3β-ol], a rare sterol detected in the opportunistic pathogen Pneumocystis carinii hominis: Structural identity and chemical synthesis
Edna S. Kaneshiro, Zunika Amit, Mardie M. Swonger, George P. Kreishman, Elwood E. Brooks, Mara Kreishman, Koka Jayasimhulu, Edward J. Parish, Hang Sun, Stephen A. Kizito, and David H. Beach
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 97–102.
PMCID: PMC15099
Biophysics
A microfabricated device for sizing and sorting DNA molecules
Hou-Pu Chou, Charles Spence, Axel Scherer, and Stephen Quake
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 11–13.
PMCID: PMC15083
Disordered water within a hydrophobic protein cavity visualized by x-ray crystallography
B. Yu, M. Blaber, A. M. Gronenborn, G. M. Clore, and D. L. D. Caspar
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 103–108.
PMCID: PMC15100
Cell Biology
Maturation of the tyrosine kinase c-src as a kinase and as a substrate depends on the molecular chaperone Hsp90
Yang Xu, Mike A. Singer, and Susan Lindquist
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 109–114.
PMCID: PMC15101
Centrosomal control of microtubule dynamics
Vladimir Rodionov, Elena Nadezhdina, and Gary Borisy
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 115–120.
PMCID: PMC15102
Calcium influx factor is synthesized by yeast and mammalian cells depleted of organellar calcium stores
Peter Csutora, Zhengchang Su, Hak Yong Kim, Andrej Bugrim, Kyle W. Cunningham, Richard Nuccitelli, Joel E. Keizer, Michael R. Hanley, J. Edwin Blalock, and Richard B. Marchase
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 121–126.
PMCID: PMC15103
Transient and stable gene expression in mammalian cells transduced with a recombinant baculovirus vector
J. Patrick Condreay, Sam M. Witherspoon, William C. Clay, and Thomas A. Kost
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 127–132.
PMCID: PMC15104
Alendronate mechanism of action: geranylgeraniol, an intermediate in the mevalonate pathway, prevents inhibition of osteoclast formation, bone resorption, and kinase activation in vitro
J. E. Fisher, M. J. Rogers, J. M. Halasy, S. P. Luckman, D. E. Hughes, P. J. Masarachia, G. Wesolowski, R. G. G. Russell, G. A. Rodan, and A. A. Reszka
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 133–138.
PMCID: PMC15105
Nuclear endpoint of Wnt signaling: Neoplastic transformation induced by transactivating lymphoid-enhancing factor 1
Masahiro Aoki, Andreas Hecht, Ulrich Kruse, Rolf Kemler, and Peter K. Vogt
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 139–144.
PMCID: PMC15106
Proapoptotic activity of Caenorhabditis elegans CED-4 protein in Drosophila: Implicated mechanisms for caspase activation
Hirotaka Kanuka, Shin Hisahara, Kazunobu Sawamoto, Shin-ichi Shoji, Hideyuki Okano, and Masayuki Miura
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 145–150.
PMCID: PMC15107
A bioluminescence resonance energy transfer (BRET) system: Application to interacting circadian clock proteins
Yao Xu, David W. Piston, and Carl Hirschie Johnson
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 151–156.
PMCID: PMC15108
Developmental Biology
Imaging of multicellular large-scale rhythmic calcium waves during zebrafish gastrulation
Edwin Gilland, Andrew L. Miller, Eric Karplus, Robert Baker, and Sarah E. Webb
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 157–161.
PMCID: PMC15109
Placental failure in mice lacking the homeobox gene Dlx3
Maria I. Morasso, Alexander Grinberg, Gertraud Robinson, Thomas D. Sargent, and Kathleen A. Mahon
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 162–167.
PMCID: PMC15110
Evolution
Self-incompatibility alleles from Physalis: Implications for historical inference from balanced genetic polymorphisms
Adam D. Richman and Joshua R. Kohn
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 168–172.
PMCID: PMC15111
Emergence of a dual-catalytic RNA with metal-specific cleavage and ligase activities: The spandrels of RNA evolution
Laura F. Landweber and Irina D. Pokrovskaya
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 173–178.
PMCID: PMC15112
Genetics
Polyglutamine-mediated dysfunction and apoptotic death of a Caenorhabditis elegans sensory neuron
Peter W. Faber, Janet R. Alter, Marcy E. MacDonald, and Anne C. Hart
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 179–184.
PMCID: PMC15113
Immunology
A two-step, two-signal model for the primary activation of precursor helper T cells
Peter A. Bretscher
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 185–190.
PMCID: PMC15114
Formation of coding joints in V(D)J recombination-inducible severe combined immune deficient pre-B cell lines
Yung Chang and Matthew L. Brown
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 191–196.
PMCID: PMC15115
A small number of residues in the class II molecule I-Au confer the ability to bind the myelin basic protein peptide Ac1-11
Cecelia I. Pearson, Anand M. Gautam, Ingrid C. Rulifson, Roland S. Liblau, and Hugh O. McDevitt
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 197–202.
PMCID: PMC15116
Medical Sciences
The BCR-ABL oncoprotein potentially interacts with the xeroderma pigmentosum group B protein
Norifumi Takeda, Masabumi Shibuya, and Yoshiro Maru
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 203–207.
PMCID: PMC15117
Segregation of steroid receptor coactivator-1 from steroid receptors in mammary epithelium
Woo-Shin Shim, James DiRenzo, James A. DeCaprio, Richard J. Santen, Myles Brown, and Meei-Huey Jeng
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 208–213.
PMCID: PMC15118
NOEY2 (ARHI), an imprinted putative tumor suppressor gene in ovarian and breast carcinomas
Yinhua Yu, Fengji Xu, Hongqi Peng, Xianjun Fang, Shulei Zhao, Yang Li, Bruce Cuevas, Wen-Lin Kuo, Joe W. Gray, Michael Siciliano, Gordon B. Mills, and Robert C. Bast, Jr.
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 214–219.
PMCID: PMC15119
Severe cardiomyopathy in mice lacking dystrophin and MyoD
Lynn A. Megeney, Boris Kablar, Robert L. S. Perry, Chuyan Ying, Linda May, and Michael A. Rudnicki
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 220–225.
PMCID: PMC15120
Decrease in telomerase activity in U-87MG human glioblastomas after treatment with an antagonist of growth hormone-releasing hormone
Hippokratis Kiaris and Andrew V. Schally
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 226–231.
PMCID: PMC15121
Virus-specific immunity after gene therapy in a murine model of severe combined immunodeficiency
Kevin D. Bunting, Kirsten J. Flynn, Janice M. Riberdy, Peter C. Doherty, and Brian P. Sorrentino
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 232–237.
PMCID: PMC15122
Toward a cancer therapy with boron-rich oligomeric phosphate diesters that target the cell nucleus
Akira Nakanishi, Lufeng Guan, Robert R. Kane, Harumi Kasamatsu, and M. Frederick Hawthorne
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 238–241.
PMCID: PMC15123
Microbiology
A natural variant of the cysteine protease virulence factor of group A Streptococcus with an arginine-glycine-aspartic acid (RGD) motif preferentially binds human integrins αvβ3 and αIIbβ3
Kathryn E. Stockbauer, Loranne Magoun, Mengyao Liu, Eugene H. Burns, Jr., Siddeswar Gubba, Sarah Renish, Xi Pan, Sarah C. Bodary, Elizabeth Baker, Jenifer Coburn, John M. Leong, and James M. Musser
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 242–247.
PMCID: PMC15124
Neurobiology
The voltage sensitive Lc-type Ca2+ channel is functionally coupled to the exocytotic machinery
Ofer Wiser, Michael Trus, Ana Hernández, Erik Renström, Sebastian Barg, Patrik Rorsman, and Daphne Atlas
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 248–253.
PMCID: PMC15125
Neuroprotection with noninvasive neurotrophin delivery to the brain
Dafang Wu and William M. Pardridge
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 254–259.
PMCID: PMC15126
Neurons in the dorsal column white matter of the spinal cord: Complex neuropil in an unexpected location
Catherine Abbadie, Kate Skinner, Igor Mitrovic, and Allan I. Basbaum
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 260–265.
PMCID: PMC15127
Pharmacology
Structural requirements of ligands for the oxysterol liver X receptors LXRα and LXRβ
Bethany A. Janowski, Michael J. Grogan, Stacey A. Jones, G. Bruce Wisely, Steven A. Kliewer, Elias J. Corey, and David J. Mangelsdorf
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 266–271.
PMCID: PMC15128
Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: The human pharmacology of a selective inhibitor of COX-2
B. F. McAdam, F. Catella-Lawson, I. A. Mardini, S. Kapoor, J. A. Lawson, and G. A. FitzGerald
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 272–277.
PMCID: PMC15129
Physiology
Atrial natriuretic peptide and oxytocin induce natriuresis by release of cGMP
T. J. Soares, T. M. Coimbra, A. R. Martins, A. G. F. Pereira, E. C. Carnio, L. G. S. Branco, W. I. C. Albuquerque-Araujo, G. de Nucci, A. L. V. Favaretto, J. Gutkowska, S. M. McCann, and J. Antunes-Rodrigues
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 278–283.
PMCID: PMC15130
Plant Biology
Isolation of a cytokinin gene, ZOG1, encoding zeatin O-glucosyltransferase from Phaseolus lunatus
Ruth C. Martin, Machteld C. Mok, and David W. S. Mok
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 284–289.
PMCID: PMC15131
The Lateral suppressor (Ls) gene of tomato encodes a new member of the VHIID protein family
Karin Schumacher, Thomas Schmitt, Mathias Rossberg, Gregor Schmitz, and Klaus Theres
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 290–295.
PMCID: PMC15132
Genes controlling fertilization-independent seed development in Arabidopsis thaliana
Ming Luo, Pierre Bilodeau, Anna Koltunow, Elizabeth S. Dennis, W. James Peacock, and Abdul M. Chaudhury
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 296–301.
PMCID: PMC15133
Diversity and molecular evolution of the RPS2 resistance gene in Arabidopsis thaliana
Ana Lucia Caicedo, Barbara A. Schaal, and Barbara N. Kunkel
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 302–306.
PMCID: PMC15134
Psychology
Mechanisms of color constancy under nearly natural viewing
J. M. Kraft and D. H. Brainard
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 307–312.
PMCID: PMC15135
Social Sciences
Anthropology
Evidence of hominid-like precision grip capability in the hand of the Miocene ape Oreopithecus
Salvador Moyà-Solà, Meike Köhler, and Lorenzo Rook
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 313–317.
PMCID: PMC15136
Corrections
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 318.
PMCID: PMC55995
Corrects: Steve A. N. Goldstein, et al. ORK1, a potassium-selective leak channel with two pore domains cloned from Drosophila melanogaster by expression in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 1996 November 12; 93(23): 13256–13261.
Proc Natl Acad Sci U S A. 1999 January 5; 96(1): 318.
PMCID: PMC55996
Corrects: Hiroaki Kawasaki, et al. A Rap guanine nucleotide exchange factor enriched highly in the basal ganglia. Proc Natl Acad Sci U S A. 1998 October 27; 95(22): 13278–13283.
Other Issues:  previous | next | latest | archive
Articles from Proceedings of the National Academy of Sciences of the United States of America are provided here courtesy of
National Academy of Sciences