| | This journal provides immediate access to some articles. Commentaries SAGE Genie: A suite with panoramic view of gene expression Peng Liang PMCID: PMC129301 An intracellular block to primate lentivirus replication Jonathan P. Stoye PMCID: PMC129302 A new name in thrombosis, ADAMTS13 J. Evan Sadler PMCID: PMC129303 Host genetic variability and West Nile virus susceptibility Charles E. Samuel PMCID: PMC129304 Continued evolutionary surprises among dinoflagellates Clifford W. Morden and Alison R. Sherwood PMCID: PMC129305 RNA traffics information systemically in plants Richard A. Jorgensen PMCID: PMC129306 Plant proteomics: blasting out of a MudPIT Julian P. Whitelegge PMCID: PMC129307 Tyrosine phosphorylation in plant cell signaling Sheng Luan PMCID: PMC129308 Perspective Physiology meets biophysics: Visualizing the interaction of hypoxia-inducible factor 1α with p300 and CBP Gregg L. Semenza PMCID: PMC129309 Physical Sciences Chemistry Formation of geometrically complex lipid nanotube-vesicle networks of higher-order topologies Mattias Karlsson, Kristin Sott, Maximillian Davidson, Ann-Sofie Cans, Pontus Linderholm, Daniel Chiu, and Owe Orwar PMCID: PMC129310 From the Cover:
Probing the transition state via photoelectron and photodetachment spectroscopy of H3O− Dong H. Zhang, Minghui Yang, Michael A. Collins, and Soo-Y. Lee PMCID: PMC129311 Creating nanocavities of tunable sizes: Hollow helices Bing Gong, Huaqiang Zeng, Jin Zhu, Lihua Yua, Yaohua Han, Shizhi Cheng, Mako Furukawa, Rubén D. Parra, Andrey Y. Kovalevsky, Jeffrey L. Mills, Ewa Skrzypczak-Jankun, Suzana Martinovic, Richard D. Smith, Chong Zheng, Thomas Szyperski, and Xiao Cheng Zeng PMCID: PMC129312 Physics Protein–DNA computation by stochastic assembly cascade Roy Bar-Ziv, Tsvi Tlusty, and Albert Libchaber PMCID: PMC129313 Biological Sciences Applied Biological Sciences Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription Adam Siddiqui-Jain, Cory L. Grand, David J. Bearss, and Laurence H. Hurley PMCID: PMC129314 Biochemistry Protein–DNA computation by stochastic assembly cascade Roy Bar-Ziv, Tsvi Tlusty, and Albert Libchaber PMCID: PMC129313 1-Cys peroxiredoxin overexpression protects cells against phospholipid peroxidation-mediated membrane damage Yefim Manevich, Tom Sweitzer, Jhang Ho Pak, Sheldon I. Feinstein, Vladimir Muzykantov, and Aron B. Fisher PMCID: PMC129315 Reactions of cysteines substituted in the amphipathic N-terminal tail of a bacterial potassium channel with hydrophilic and hydrophobic maleimides Jing Li, Qiang Xu, D. Marien Cortes, Eduardo Perozo, Aaron Laskey, and Arthur Karlin PMCID: PMC129316 Dynamic and clustering model of bacterial chemotaxis receptors: Structural basis for signaling and high sensitivity Sung-Hou Kim, Weiru Wang, and Kyeong Kyu Kim PMCID: PMC129317 Isolation of high-affinity GTP aptamers from partially structured RNA libraries Jonathan H. Davis and Jack W. Szostak PMCID: PMC129318 SALSA, a variant of yeast SAGA, contains truncated Spt7, which correlates with activated transcription David E. Sterner, Rimma Belotserkovskaya, and Shelley L. Berger PMCID: PMC129319 Phytochrome from Agrobacterium tumefaciens has unusual spectral properties and reveals an N-terminal chromophore attachment site Tilman Lamparter, Norbert Michael, Franz Mittmann, and Berta Esteban PMCID: PMC129320 INAUGURAL ARTICLE by a Recently Elected Academy Member: A linear lattice model for polyglutamine in CAG-expansion diseases Melanie J. Bennett, Kathryn E. Huey-Tubman, Andrew B. Herr, Anthony P. West, Jr., Scott A. Ross, and Pamela J. Bjorkman PMCID: PMC129321 The tobacco salicylic acid-binding protein 3 (SABP3) is the chloroplast carbonic anhydrase, which exhibits antioxidant activity and plays a role in the hypersensitive defense response David H. Slaymaker, Duroy A. Navarre, Daniel Clark, Olga del Pozo, Gregory B. Martin, and Daniel F. Klessig PMCID: PMC129322 A far-red fluorescent protein with fast maturation and reduced oligomerization tendency from Entacmaea quadricolor (Anthozoa, Actinaria) Jörg Wiedenmann, Andreas Schenk, Carlheinz Röcker, Andreas Girod, Klaus-Dieter Spindler, and G. Ulrich Nienhaus PMCID: PMC129323 The C2A domain of JFC1 binds to 3′-phosphorylated phosphoinositides and directs plasma membrane association in living cells Sergio D. Catz, Jennifer L. Johnson, and Bernard M. Babior PMCID: PMC129324 Evidence against stabilization of the transition state oxyanion by a pKa-perturbed RNA base in the peptidyl transferase center K. Mark Parnell, Amy C. Seila, and Scott A. Strobel PMCID: PMC129325 Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline Scott A. Lesley, Peter Kuhn, Adam Godzik, Ashley M. Deacon, Irimpan Mathews, Andreas Kreusch, Glen Spraggon, Heath E. Klock, Daniel McMullan, Tanya Shin, Juli Vincent, Alyssa Robb, Linda S. Brinen, Mitchell D. Miller, Timothy M. McPhillips, Mark A. Miller, Daniel Scheibe, Jaume M. Canaves, Chittibabu Guda, Lukasz Jaroszewski, Thomas L. Selby, Marc-Andre Elsliger, John Wooley, Susan S. Taylor, Keith O. Hodgson, Ian A. Wilson, Peter G. Schultz, and Raymond C. Stevens PMCID: PMC129326 Structural insights into peptide bond formation Jeffrey L. Hansen, T. Martin Schmeing, Peter B. Moore, and Thomas A. Steitz PMCID: PMC129327 Biophysics From the Cover:
Specificity of RNA–RNA helix recognition Daniel J. Battle and Jennifer A. Doudna PMCID: PMC129328 Using mechanical force to probe the mechanism of pausing and arrest during continuous elongation by Escherichia coli RNA polymerase Nancy R. Forde, David Izhaky, Glenna R. Woodcock, Gijs J. L. Wuite, and Carlos Bustamante PMCID: PMC129329 Arrangement of RecA protein in its active filament determined by polarized-light spectroscopy Katsumi Morimatsu, Masayuki Takahashi, and Bengt Nordén PMCID: PMC129330 Cell Biology Sterols block binding of COPII proteins to SCAP, thereby controlling SCAP sorting in ER Peter J. Espenshade, Wei-Ping Li, and Daisuke Yabe PMCID: PMC129331 The histone deacetylase inhibitor SAHA arrests cancer cell growth, up-regulates thioredoxin-binding protein-2, and down-regulates thioredoxin Lisa M. Butler, Xianbo Zhou, Wei-Sheng Xu, Howard I. Scher, Richard A. Rifkind, Paul A. Marks, and Victoria M. Richon PMCID: PMC129332 Male germ-line stem cell potential is predicted by morphology of cells in neonatal rat testes Kyle E. Orwig, Buom-Yong Ryu, Mary R. Avarbock, and Ralph L. Brinster PMCID: PMC129333 Developmental Biology TCL1 participates in early embryonic development and is overexpressed in human seminomas Maria Grazia Narducci, Maria Teresa Fiorenza, Sang-Moo Kang, Arturo Bevilacqua, Monica Di Giacomo, Daniele Remotti, Maria Cristina Picchio, Vincenzo Fidanza, Max D. Cooper, Carlo Maria Croce, Franco Mangia, and Giandomenico Russo PMCID: PMC129334 Evolution Circadian genes in a blind subterranean mammal II: Conservation and uniqueness of the three Period homologs in the blind subterranean mole rat, Spalax ehrenbergi superspecies Aaron Avivi, Henrik Oster, Alma Joel, Avigdor Beiles, Urs Albrecht, and Eviatar Nevo PMCID: PMC129335 A single origin of the peridinin- and fucoxanthin-containing plastids in dinoflagellates through tertiary endosymbiosis Hwan Su Yoon, Jeremiah D. Hackett, and Debashish Bhattacharya PMCID: PMC129336 Ancient mitochondrial haplotypes and evidence for intragenic recombination in a gynodioecious plant Thomas Städler and Lynda F. Delph PMCID: PMC129337 Inactivation of CMP-N-acetylneuraminic acid hydroxylase occurred prior to brain expansion during human evolution Hsun-Hua Chou, Toshiyuki Hayakawa, Sandra Diaz, Matthias Krings, Etty Indriati, Meave Leakey, Svante Paabo, Yoko Satta, Naoyuki Takahata, and Ajit Varki PMCID: PMC129338 Loss of microsatellite diversity and low effective population size in an overexploited population of New Zealand snapper (Pagrus auratus) Lorenz Hauser, Greg J. Adcock, Peter J. Smith, Julio H. Bernal Ramírez, and Gary R. Carvalho PMCID: PMC129339 Evidence for an ancient selective sweep in the MHC class I gene repertoire of chimpanzees Natasja G. de Groot, Nel Otting, Gaby G. M. Doxiadis, Sunita S. Balla-Jhagjhoorsingh, Jonathan L. Heeney, Jon J. van Rood, Pascal Gagneux, and Ronald E. Bontrop PMCID: PMC129340 Genetics The novel Rho-GTPase activating gene MEGAP/ srGAP3 has a putative role in severe mental retardation Volker Endris, Birgit Wogatzky, Uwe Leimer, Dusan Bartsch, Malgorzata Zatyka, Farida Latif, Eamonn R. Maher, Gholamali Tariverdian, Stefan Kirsch, Dieter Karch, and Gudrun A. Rappold PMCID: PMC129341 Cooperative activities of hematopoietic regulators recruit RNA polymerase II to a tissue-specific chromatin domain Kirby D. Johnson, Jeffrey A. Grass, Meghan E. Boyer, Carol M. Kiekhaefer, Gerd A. Blobel, Mitchell J. Weiss, and Emery H. Bresnick PMCID: PMC129342 Evidence for a susceptibility gene (SLEH1) on chromosome 11q14 for systemic lupus erythematosus (SLE) families with hemolytic anemia Jennifer A. Kelly, Kevin Thompson, Jeff Kilpatrick, Tom Lam, Swapan K. Nath, Courtney Gray-McGuire, Jeff Reid, Bahram Namjou, Christopher E. Aston, Gail R. Bruner, R. Hal Scofield, and John B. Harley PMCID: PMC129343 Identification of the binding sites of regulatory proteins in bacterial genomes Hao Li, Virgil Rhodius, Carol Gross, and Eric D. Siggia PMCID: PMC129344 A duplicated copy of DMRT1 in the sex-determining region of the Y chromosome of the medaka, Oryzias latipes Indrajit Nanda, Mariko Kondo, Ute Hornung, Shuichi Asakawa, Christoph Winkler, Atsushi Shimizu, Zhihong Shan, Thomas Haaf, Nobuyoshi Shimizu, Akihiro Shima, Michael Schmid, and Manfred Schartl PMCID: PMC129345 Specification of unique Pit-1 activity in the hGH locus control region Brian M. Shewchuk, Stephen A. Liebhaber, and Nancy E. Cooke PMCID: PMC129346 Immunology Modulation of TCR-induced transcriptional profiles by ligation of CD28, ICOS, and CTLA-4 receptors James L. Riley, Mao Mao, Sumire Kobayashi, Matt Biery, Julja Burchard, Guy Cavet, Brian P. Gregson, Carl H. June, and Peter S. Linsley PMCID: PMC129347 Genomic expression programs and the integration of the CD28 costimulatory signal in T cell activation Maximilian Diehn, Ash A. Alizadeh, Oliver J. Rando, Chih Long Liu, Kryn Stankunas, David Botstein, Gerald R. Crabtree, and Patrick O. Brown PMCID: PMC129348 Functional plasticity of an antigen-specific memory CD4 T cell population Mojgan Ahmadzadeh and Donna L. Farber PMCID: PMC129349 Dysregulated T helper cell differentiation in the absence of interferon regulatory factor 4 Michael Lohoff, Hans-Willi Mittrücker, Stefan Prechtl, Susi Bischof, Frank Sommer, Sonja Kock, David A. Ferrick, Gordon S. Duncan, Andre Gessner, and Tak W. Mak PMCID: PMC129350 CD8+ T cell responses against a dominant cryptic HLA-A2 epitope after NY-ESO-1 peptide immunization of cancer patients Sacha Gnjatic, Elke Jäger, Weisan Chen, Nasser K. Altorki, Mitsutoshi Matsuo, Sang-Yull Lee, Qiyuan Chen, Yasuhiro Nagata, Djordje Atanackovic, Yao-Tseng Chen, Gerd Ritter, Jonathan Cebon, Alexander Knuth, and Lloyd J. Old PMCID: PMC129351 Short-term antigen presentation and single clonal burst limit the magnitude of the CD8+ T cell responses to malaria liver stages Julius C. R. Hafalla, Gen-ichiro Sano, Luzia H. Carvalho, Alexandre Morrot, and Fidel Zavala PMCID: PMC129352 Medical Sciences Febrile temperatures induce cytoadherence of ring-stage Plasmodium falciparum-infected erythrocytes Rachanee Udomsangpetch, Busaba Pipitaporn, Kamolrat Silamut, Robert Pinches, Sue Kyes, Sornchai Looareesuwan, Christopher Newbold, and Nicholas J. White PMCID: PMC129353 The Alzheimer's Aβ-peptide is deposited at sites of complement activation in pathologic deposits associated with aging and age-related macular degeneration Lincoln V. Johnson, William P. Leitner, Alexander J. Rivest, Michelle K. Staples, Monte J. Radeke, and Don H. Anderson PMCID: PMC129354 Identification of a transcriptionally active peroxisome proliferator-activated receptor α-interacting cofactor complex in rat liver and characterization of PRIC285 as a coactivator Sailesh Surapureddi, Songtao Yu, Hengfu Bu, Takashi Hashimoto, Anjana V. Yeldandi, Papreddy Kashireddy, Mustapha Cherkaoui-Malki, Chao Qi, Yi-Jun Zhu, M. Sambasiva Rao, and Janardan K. Reddy PMCID: PMC129355 Crosslinked HIV-1 envelope–CD4 receptor complexes elicit broadly cross-reactive neutralizing antibodies in rhesus macaques Timothy Fouts, Karla Godfrey, Kathryn Bobb, David Montefiori, Carl V. Hanson, V. S. Kalyanaraman, Anthony DeVico, and Ranajit Pal PMCID: PMC129356 PPARα is necessary for the lipopenic action of hyperleptinemia on white adipose and liver tissue Y. Lee, X. Yu, F. Gonzales, D. J. Mangelsdorf, May-Yun Wang, C. Richardson, L. A. Witters, and R. H. Unger PMCID: PMC129357 Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy Guang-Ping Gao, Mauricio R. Alvira, Lili Wang, Roberto Calcedo, Julie Johnston, and James M. Wilson PMCID: PMC129358 Essential myosin light chain as a target for caspase-3 in failing myocardium Alessandra Moretti, Hans-Jörg Weig, Thomas Ott, Melchior Seyfarth, Hans-Peter Holthoff, Diana Grewe, Angelika Gillitzer, Lorenz Bott-Flügel, Albert Schömig, Martin Ungerer, and Karl-Ludwig Laugwitz PMCID: PMC129359 The expression of growth hormone-releasing hormone (GHRH) and splice variants of its receptor in human gastroenteropancreatic carcinomas Rebeca Busto, Andrew V. Schally, Jozsef L. Varga, M. Olga Garcia-Fernandez, Kate Groot, Patricia Armatis, and Karoly Szepeshazi PMCID: PMC129360 Prospective isolation of human clonogenic common myeloid progenitors Markus G. Manz, Toshihiro Miyamoto, Koichi Akashi, and Irving L. Weissman PMCID: PMC129361 Epstein–Barr virus EBNA2 blocks Nur77- mediated apoptosis Jae Myun Lee, Kyoung-Ho Lee, Magdalena Weidner, Barbara A. Osborne, and S. Diane Hayward PMCID: PMC129362 Huntington's disease age-of-onset linked to polyglutamine aggregation nucleation Songming Chen, Frank A. Ferrone, and Ronald Wetzel PMCID: PMC129363 The program of androgen-responsive genes in neoplastic prostate epithelium Peter S. Nelson, Nigel Clegg, Hugh Arnold, Camari Ferguson, Michael Bonham, James White, Leroy Hood, and Biaoyang Lin PMCID: PMC129364 Identification of macrophage liver X receptors as inhibitors of atherosclerosis Rajendra K. Tangirala, Eric D. Bischoff, Sean B. Joseph, Brandee L. Wagner, Robert Walczak, Bryan A. Laffitte, Chris L. Daige, Diane Thomas, Richard A. Heyman, David J. Mangelsdorf, Xuping Wang, Aldons J. Lusis, Peter Tontonoz, and Ira G. Schulman PMCID: PMC129365 Mutations and common polymorphisms in ADAMTS13 gene responsible for von Willebrand factor-cleaving protease activity Koichi Kokame, Masanori Matsumoto, Kenji Soejima, Hideo Yagi, Hiromichi Ishizashi, Masahisa Funato, Hiroshi Tamai, Mutsuko Konno, Kei Kamide, Yuhei Kawano, Toshiyuki Miyata, and Yoshihiro Fujimura PMCID: PMC129366 Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants Albena T. Dinkova-Kostova, W. David Holtzclaw, Robert N. Cole, Ken Itoh, Nobunao Wakabayashi, Yasutake Katoh, Masayuki Yamamoto, and Paul Talalay PMCID: PMC129367 Microbiology From the Cover:
Cellular inhibitors with Fv1-like activity restrict human and simian immunodeficiency virus tropism Simone Cowan, Theodora Hatziioannou, Tshaka Cunningham, Mark A. Muesing, Heinrich G. Gottlinger, and Paul D. Bieniasz PMCID: PMC129368 Restriction of lentivirus in monkeys Caroline Besnier, Yasuhiro Takeuchi, and Greg Towers PMCID: PMC129369 Neurobiology RNAi functions in cultured mammalian neurons Anna M. Krichevsky and Kenneth S. Kosik PMCID: PMC129370 The clothing effect: Tactile neurons in the precentral gyrus do not respond to the touch of the familiar primate chair Michael S. A. Graziano, Shalani E. Alisharan, Xintian Hu, and Charles G. Gross PMCID: PMC129371 Salvinorin A: A potent naturally occurring nonnitrogenous κ opioid selective agonist Bryan L. Roth, Karen Baner, Richard Westkaemper, Daniel Siebert, Kenner C. Rice, SeAnna Steinberg, Paul Ernsberger, and Richard B. Rothman PMCID: PMC129372 Synergistic interaction between adenosine A2A and glutamate mGlu5 receptors: Implications for striatal neuronal function Sergi Ferré, Marzena Karcz-Kubicha, Bruce T. Hope, Patrizia Popoli, Javier Burgueño, M. Angeles Gutiérrez, Vicent Casadó, Kjell Fuxe, Steven R. Goldberg, Carme Lluis, Rafael Franco, and Francisco Ciruela PMCID: PMC129373 Vascular endothelial growth factor (VEGF) stimulates neurogenesis in vitro and in vivo Kunlin Jin, Yonghua Zhu, Yunjuan Sun, Xiao Ou Mao, Lin Xie, and David A. Greenberg PMCID: PMC129374 Physiology VEGF increases engraftment of bone marrow-derived endothelial progenitor cells (EPCs) into vasculature of newborn murine recipients Pampee P. Young, A. Alex Hofling, and Mark S. Sands PMCID: PMC129375 PDZ-domain interactions and apical expression of type IIa Na/Pi cotransporters Nati Hernando, Nadine Déliot, Serge M. Gisler, Eleanor Lederer, Edward J. Weinman, Jürg Biber, and Heini Murer PMCID: PMC129376 Plant Biology From the Cover:
Evidence for a role for protein tyrosine phosphatase in the control of ion release from the guard cell vacuole in stomatal closure Enid A. C. MacRobbie PMCID: PMC129377 From the Cover:
Proteomic survey of metabolic pathways in rice Antonius Koller, Michael P. Washburn, B. Markus Lange, Nancy L. Andon, Cosmin Deciu, Paul A. Haynes, Lara Hays, David Schieltz, Ryan Ulaszek, Jing Wei, Dirk Wolters, and John R. Yates, III PMCID: PMC129378 Stimulation of the cell cycle and maize transformation by disruption of the plant retinoblastoma pathway William Gordon-Kamm, Brian P. Dilkes, Keith Lowe, George Hoerster, Xifan Sun, Margit Ross, Laura Church, Chris Bunde, Jeff Farrell, Patrea Hill, Sheila Maddock, Jane Snyder, Louisa Sykes, Zhongsen Li, Young-min Woo, Dennis Bidney, and Brian A. Larkins PMCID: PMC129379 High molecular weight RNAs and small interfering RNAs induce systemic posttranscriptional gene silencing in plants Ulrich Klahre, Patrice Crété, Sabrina A. Leuenberger, Victor A. Iglesias, and Frederick Meins, Jr. PMCID: PMC129380 Psychology Sleep forms memory for finger skills Stefan Fischer, Manfred Hallschmid, Anna Lisa Elsner, and Jan Born PMCID: PMC129381 |
